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Recent Studies On Risk Analysis And Statistical Modeling


Recent Studies On Risk Analysis And Statistical Modeling
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Recent Studies On Risk Analysis And Statistical Modeling


Recent Studies On Risk Analysis And Statistical Modeling
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Author : Teresa A. Oliveira
language : en
Publisher: Springer
Release Date : 2018-08-22

Recent Studies On Risk Analysis And Statistical Modeling written by Teresa A. Oliveira and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-22 with Mathematics categories.


This book provides an overview of the latest developments in the field of risk analysis (RA). Statistical methodologies have long-since been employed as crucial decision support tools in RA. Thus, in the context of this new century, characterized by a variety of daily risks - from security to health risks - the importance of exploring theoretical and applied issues connecting RA and statistical modeling (SM) is self-evident. In addition to discussing the latest methodological advances in these areas, the book explores applications in a broad range of settings, such as medicine, biology, insurance, pharmacology and agriculture, while also fostering applications in newly emerging areas. This book is intended for graduate students as well as quantitative researchers in the area of RA.



Risk Analysis Foundations Models And Methods


Risk Analysis Foundations Models And Methods
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Author : Louis Anthony Cox Jr.
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Risk Analysis Foundations Models And Methods written by Louis Anthony Cox Jr. and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Business & Economics categories.


Risk Analysis: Foundations, Models, and Methods fully addresses the questions of "What is health risk analysis?" and "How can its potentialities be developed to be most valuable to public health decision-makers and other health risk managers?" Risk analysis provides methods and principles for answering these questions. It is divided into methods for assessing, communicating, and managing health risks. Risk assessment quantitatively estimates the health risks to individuals and to groups from hazardous exposures and from the decisions or activities that create them. It applies specialized models and methods to quantify likely exposures and their resulting health risks. Its goal is to produce information to improve decisions. It does this by relating alternative decisions to their probable consequences and by identifying those decisions that make preferred outcomes more likely. Health risk assessment draws on explicit engineering, biomathematical, and statistical consequence models to describe or simulate the causal relations between actions and their probable effects on health. Risk communication characterizes and presents information about health risks and uncertainties to decision-makers and stakeholders. Risk management applies principles for choosing among alternative decision alternatives or actions that affect exposure, health risks, or their consequences.



Recent Applications Of Financial Risk Modelling And Portfolio Management


Recent Applications Of Financial Risk Modelling And Portfolio Management
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Author : Škrinjari?, Tihana
language : en
Publisher: IGI Global
Release Date : 2020-09-25

Recent Applications Of Financial Risk Modelling And Portfolio Management written by Škrinjari?, Tihana and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-25 with Business & Economics categories.


In today’s financial market, portfolio and risk management are facing an array of challenges. This is due to increasing levels of knowledge and data that are being made available that have caused a multitude of different investment models to be explored and implemented. Professionals and researchers in this field are in need of up-to-date research that analyzes these contemporary models of practice and keeps pace with the advancements being made within financial risk modelling and portfolio control. Recent Applications of Financial Risk Modelling and Portfolio Management is a pivotal reference source that provides vital research on the use of modern data analysis as well as quantitative methods for developing successful portfolio and risk management techniques. While highlighting topics such as credit scoring, investment strategies, and budgeting, this publication explores diverse models for achieving investment goals as well as improving upon traditional financial modelling methods. This book is ideally designed for researchers, financial analysts, executives, practitioners, policymakers, academicians, and students seeking current research on contemporary risk management strategies in the financial sector.



Statistical Modeling In Biomedical Research


Statistical Modeling In Biomedical Research
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Author : Yichuan Zhao
language : en
Publisher: Springer Nature
Release Date : 2020-03-19

Statistical Modeling In Biomedical Research written by Yichuan Zhao and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-19 with Medical categories.


This edited collection discusses the emerging topics in statistical modeling for biomedical research. Leading experts in the frontiers of biostatistics and biomedical research discuss the statistical procedures, useful methods, and their novel applications in biostatistics research. Interdisciplinary in scope, the volume as a whole reflects the latest advances in statistical modeling in biomedical research, identifies impactful new directions, and seeks to drive the field forward. It also fosters the interaction of scholars in the arena, offering great opportunities to stimulate further collaborations. This book will appeal to industry data scientists and statisticians, researchers, and graduate students in biostatistics and biomedical science. It covers topics in: Next generation sequence data analysis Deep learning, precision medicine, and their applications Large scale data analysis and its applications Biomedical research and modeling Survival analysis with complex data structure and its applications.



Statistical Models In Toxicology


Statistical Models In Toxicology
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Author : Mehdi Razzaghi
language : en
Publisher: CRC Press
Release Date : 2020-05-21

Statistical Models In Toxicology written by Mehdi Razzaghi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-21 with Mathematics categories.


Statistical Models in Toxicology presents an up-to-date and comprehensive account of mathematical statistics problems that occur in toxicology. This is as an exciting time in toxicology because of the attention given by statisticians to the problem of estimating the human health risk for environmental and occupational exposures. The development of modern statistical techniques with solid mathematical foundations in the 20th century and the advent of modern computers in the latter part of the century gave way to development of many statistical models and methods to describe toxicological processes and attempts to solve the associated problems. Not only have the models enjoyed a high level of elegance and sophistication mathematically, they are widely used by industry and government regulatory agencies. Features: Focuses on describing the statistical models in environmental toxicology that facilitate the assessment of risk mainly in humans. The properties and shortfalls of each model are discussed and its impact in the process of risk assessment is examined. Discusses models that assess the risk of mixtures of chemicals. Presents statistical models that are developed for risk estimation in different aspects of environmental toxicology including cancer and carcinogenic substances. Includes models for developmental and reproductive toxicity risk assessment, risk assessment in continuous outcomes and developmental neurotoxicity. Contains numerous examples and exercises. Statistical Models in Toxicology introduces a wide variety of statistical models that are currently utilized for dose-response modeling and risk analysis. These models are often developed based on design and regulatory guidelines of toxicological experiments. The book is suitable for practitioners or as use as a textbook for advanced undergraduate or graduate students of mathematics and statistics.



Case Studies In Bayesian Statistical Modelling And Analysis


Case Studies In Bayesian Statistical Modelling And Analysis
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Author : Clair L. Alston
language : en
Publisher: John Wiley & Sons
Release Date : 2012-10-10

Case Studies In Bayesian Statistical Modelling And Analysis written by Clair L. Alston and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-10 with Mathematics categories.


Provides an accessible foundation to Bayesian analysis using real world models This book aims to present an introduction to Bayesian modelling and computation, by considering real case studies drawn from diverse fields spanning ecology, health, genetics and finance. Each chapter comprises a description of the problem, the corresponding model, the computational method, results and inferences as well as the issues that arise in the implementation of these approaches. Case Studies in Bayesian Statistical Modelling and Analysis: Illustrates how to do Bayesian analysis in a clear and concise manner using real-world problems. Each chapter focuses on a real-world problem and describes the way in which the problem may be analysed using Bayesian methods. Features approaches that can be used in a wide area of application, such as, health, the environment, genetics, information science, medicine, biology, industry and remote sensing. Case Studies in Bayesian Statistical Modelling and Analysis is aimed at statisticians, researchers and practitioners who have some expertise in statistical modelling and analysis, and some understanding of the basics of Bayesian statistics, but little experience in its application. Graduate students of statistics and biostatistics will also find this book beneficial.



Recent Advances In Quantitative Methods In Cancer And Human Health Risk Assessment


Recent Advances In Quantitative Methods In Cancer And Human Health Risk Assessment
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Author : Lutz Edler
language : en
Publisher: John Wiley & Sons
Release Date : 2005-05-27

Recent Advances In Quantitative Methods In Cancer And Human Health Risk Assessment written by Lutz Edler and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-27 with Mathematics categories.


Human health risk assessment involves the measuring of risk of exposure to disease, with a view to improving disease prevention. Mathematical, biological, statistical, and computational methods play a key role in exposure assessment, hazard assessment and identification, and dose-response modelling. Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment is a comprehensive text that accounts for the wealth of new biological data as well as new biological, toxicological, and medical approaches adopted in risk assessment. It provides an authoritative compendium of state-of-the-art methods proposed and used, featuring contributions from eminent authors with varied experience from academia, government, and industry. Provides a comprehensive summary of currently available quantitative methods for risk assessment of both cancer and non-cancer problems. Describes the applications and the limitations of current mathematical modelling and statistical analysis methods (classical and Bayesian). Includes an extensive introduction and discussion to each chapter. Features detailed studies of risk assessments using biologically-based modelling approaches. Discusses the varying computational aspects of the methods proposed. Provides a global perspective on human health risk assessment by featuring case studies from a wide range of countries. Features an extensive bibliography with links to relevant background information within each chapter. Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment will appeal to researchers and practitioners in public health & epidemiology, and postgraduate students alike. It will also be of interest to professionals working in risk assessment agencies.



Scientific Review Of The Proposed Risk Assessment Bulletin From The Office Of Management And Budget


Scientific Review Of The Proposed Risk Assessment Bulletin From The Office Of Management And Budget
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2007-04-16

Scientific Review Of The Proposed Risk Assessment Bulletin From The Office Of Management And Budget written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-16 with Political Science categories.


Risk assessments are often used by the federal government to estimate the risk the public may face from such things as exposure to a chemical or the potential failure of an engineered structure, and they underlie many regulatory decisions. Last January, the White House Office of Management and Budget (OMB) issued a draft bulletin for all federal agencies, which included a new definition of risk assessment and proposed standards aimed at improving federal risk assessments. This National Research Council report, written at the request of OMB, evaluates the draft bulletin and supports its overall goals of improving the quality of risk assessments. However, the report concludes that the draft bulletin is "fundamentally flawed" from a scientific and technical standpoint and should be withdrawn. Problems include an overly broad definition of risk assessment in conflict with long-established concepts and practices, and an overly narrow definition of adverse health effects-one that considers only clinically apparent effects to be adverse, ignoring other biological changes that could lead to health effects. The report also criticizes the draft bulletin for focusing mainly on human health risk assessments while neglecting assessments of technology and engineered structures.



Selected Water Resources Abstracts


Selected Water Resources Abstracts
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Author :
language : en
Publisher:
Release Date : 1990

Selected Water Resources Abstracts written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Water categories.




Economic Evaluation Of Cancer Drugs


Economic Evaluation Of Cancer Drugs
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Author : Iftekhar Khan
language : en
Publisher: CRC Press
Release Date : 2019-06-14

Economic Evaluation Of Cancer Drugs written by Iftekhar Khan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-14 with Mathematics categories.


Cancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems. With advances in the diagnosis and treatment, more people are diagnosed early and receive treatments for a disease where few treatments options were previously available. As a result, the survival of patients with cancer has steadily improved and, in most cases, patients who are not cured may receive multiple lines of treatment, often with financial consequences for the patients, insurers and healthcare systems. Although many books exist that address economic evaluation, Economic Evaluation of Cancer Drugs using Clinical Trial and Real World Data is the first unified text that specifically addresses the economic evaluation of cancer drugs. The authors discuss how to perform cost-effectiveness analyses while emphasising the strategic importance of designing cost-effectiveness into cancer trials and building robust economic evaluation models that have a higher chance of reimbursement if truly cost-effective. They cover the use of real-world data using cancer registries and discuss how such data can support or complement clinical trials with limited follow up. Lessons learned from failed reimbursement attempts, factors predictive of successful reimbursement and the different payer requirements across major countries including US, Australia, Canada, UK, Germany, France and Italy are also discussed. The book includes many detailed practical examples, case studies and thought-provoking exercises for use in classroom and seminar discussions. Iftekhar Khan is a medical statistician and health economist and a lead statistician at Oxford Unviersity’s Center for Statistics in Medicine. Professor Khan is also a Senior Research Fellow in Health Economics at University of Warwick and is a Senior Statistical Assessor within the Licensing Division of the UK Medicine and Health Regulation Agency. Ralph Crott is a former professor in Pharmacoeconomics at the University of Montreal in Quebec, Canada and former head of the EORTC Health Economics Unit and former senior health economist at the Belgian HTA organization. Zahid Bashir has over twelve years experience working in the pharmaceutical industry in medical affairs and oncology drug development where he is involved in the design and execution of oncology clinical trials and development of reimbursement dossiers for HTA submission.