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Statistical Modeling In Biomedical Research


Statistical Modeling In Biomedical Research
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Statistical Modeling For Biomedical Researchers


Statistical Modeling For Biomedical Researchers
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Author : William D. Dupont
language : en
Publisher: Cambridge University Press
Release Date : 2009-02-12

Statistical Modeling For Biomedical Researchers written by William D. Dupont and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-12 with Medical categories.


A second edition of the easy-to-use standard text guiding biomedical researchers in the use of advanced statistical methods.



Statistical Modeling In Biomedical Research


Statistical Modeling In Biomedical Research
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Author : Yichuan Zhao
language : en
Publisher: Springer Nature
Release Date : 2020-03-19

Statistical Modeling In Biomedical Research written by Yichuan Zhao and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-19 with Medical categories.


This edited collection discusses the emerging topics in statistical modeling for biomedical research. Leading experts in the frontiers of biostatistics and biomedical research discuss the statistical procedures, useful methods, and their novel applications in biostatistics research. Interdisciplinary in scope, the volume as a whole reflects the latest advances in statistical modeling in biomedical research, identifies impactful new directions, and seeks to drive the field forward. It also fosters the interaction of scholars in the arena, offering great opportunities to stimulate further collaborations. This book will appeal to industry data scientists and statisticians, researchers, and graduate students in biostatistics and biomedical science. It covers topics in: Next generation sequence data analysis Deep learning, precision medicine, and their applications Large scale data analysis and its applications Biomedical research and modeling Survival analysis with complex data structure and its applications.



Statistical Modeling In Biomedical Research


Statistical Modeling In Biomedical Research
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Author :
language : en
Publisher:
Release Date : 2020

Statistical Modeling In Biomedical Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Biometry categories.


This edited collection discusses the emerging topics in statistical modeling for biomedical research. Leading experts in the frontiers of biostatistics and biomedical research discuss the statistical procedures, useful methods, and their novel applications in biostatistics research. Interdisciplinary in scope, the volume as a whole reflects the latest advances in statistical modeling in biomedical research, identifies impactful new directions, and seeks to drive the field forward. It also fosters the interaction of scholars in the arena, offering great opportunities to stimulate further collaborations. This book will appeal to industry data scientists and statisticians, researchers, and graduate students in biostatistics and biomedical science. It covers topics in: Next generation sequence data analysis Deep learning, precision medicine, and their applications Large scale data analysis and its applications Biomedical research and modeling Survival analysis with complex data structure and its applications.



Essential Statistical Methods For Medical Statistics


Essential Statistical Methods For Medical Statistics
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Author : J. Philip Miller
language : en
Publisher: Elsevier
Release Date : 2010-11-08

Essential Statistical Methods For Medical Statistics written by J. Philip Miller and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-08 with Mathematics categories.


Essential Statistical Methods for Medical Statistics presents only key contributions which have been selected from the volume in the Handbook of Statistics: Medical Statistics, Volume 27 (2009). While the use of statistics in these fields has a long and rich history, the explosive growth of science in general, and of clinical and epidemiological sciences in particular, has led to the development of new methods and innovative adaptations of standard methods. This volume is appropriately focused for individuals working in these fields. Contributors are internationally renowned experts in their respective areas. - Contributors are internationally renowned experts in their respective areas - Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research - Methods for assessing Biomarkers, analysis of competing risks - Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs - Structural equations modelling and longitudinal data analysis



Statistical Modeling For Biomedical Researchers


Statistical Modeling For Biomedical Researchers
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Author : William D. Dupont
language : en
Publisher: Cambridge University Press
Release Date : 2002-11-28

Statistical Modeling For Biomedical Researchers written by William D. Dupont and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-11-28 with Medical categories.


This text enables biomedical researchers to use a number of advanced statistical methods that have proven valuable in medical research, and uses a statistical software package (Stata® ) to avoid mathematics beyond the high school level. Intended for people who have had an introductory course in biostatistics, the volume emphasizes the assumptions underlying each method, using exploratory techniques to determine the most appropriate method. It presents results in a way that will be readily understood by clinical colleagues. Numerous real examples from medical literature and graphical methods are used to illustrate these techniques.



Statistical Modeling For Biomedical Researchers


Statistical Modeling For Biomedical Researchers
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Author : William Dudley Dupont
language : en
Publisher:
Release Date : 2014-05-14

Statistical Modeling For Biomedical Researchers written by William Dudley Dupont and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Medical categories.


New edition of the easy-to-use standard text guiding biomedical researchers in the use of advanced statistical methods.



Handbook Of Statistical Modeling For The Social And Behavioral Sciences


Handbook Of Statistical Modeling For The Social And Behavioral Sciences
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Author : G. Arminger
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Handbook Of Statistical Modeling For The Social And Behavioral Sciences written by G. Arminger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Psychology categories.


Contributors thoroughly survey the most important statistical models used in empirical reserch in the social and behavioral sciences. Following a common format, each chapter introduces a model, illustrates the types of problems and data for which the model is best used, provides numerous examples that draw upon familiar models or procedures, and includes material on software that can be used to estimate the models studied. This handbook will aid researchers, methodologists, graduate students, and statisticians to understand and resolve common modeling problems.



Regression Models As A Tool In Medical Research


Regression Models As A Tool In Medical Research
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Author : Werner Vach
language : en
Publisher: CRC Press
Release Date : 2012-11-27

Regression Models As A Tool In Medical Research written by Werner Vach and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-27 with Mathematics categories.


While regression models have become standard tools in medical research, understanding how to properly apply the models and interpret the results is often challenging for beginners. Regression Models as a Tool in Medical Research presents the fundamental concepts and important aspects of regression models most commonly used in medical research, including the classical regression model for continuous outcomes, the logistic regression model for binary outcomes, and the Cox proportional hazards model for survival data. The text emphasizes adequate use, correct interpretation of results, appropriate presentation of results, and avoidance of potential pitfalls. After reviewing popular models and basic methods, the book focuses on advanced topics and techniques. It considers the comparison of regression coefficients, the selection of covariates, the modeling of nonlinear and nonadditive effects, and the analysis of clustered and longitudinal data, highlighting the impact of selection mechanisms, measurement error, and incomplete covariate data. The text then covers the use of regression models to construct risk scores and predictors. It also gives an overview of more specific regression models and their applications as well as alternatives to regression modeling. The mathematical details underlying the estimation and inference techniques are provided in the appendices.



Epidemiology And Medical Statistics


Epidemiology And Medical Statistics
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Author :
language : en
Publisher: Elsevier
Release Date : 2007-11-21

Epidemiology And Medical Statistics written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-21 with Mathematics categories.


This volume, representing a compilation of authoritative reviews on a multitude of uses of statistics in epidemiology and medical statistics written by internationally renowned experts, is addressed to statisticians working in biomedical and epidemiological fields who use statistical and quantitative methods in their work. While the use of statistics in these fields has a long and rich history, explosive growth of science in general and clinical and epidemiological sciences in particular have gone through a see of change, spawning the development of new methods and innovative adaptations of standard methods. Since the literature is highly scattered, the Editors have undertaken this humble exercise to document a representative collection of topics of broad interest to diverse users. The volume spans a cross section of standard topics oriented toward users in the current evolving field, as well as special topics in much need which have more recent origins. This volume was prepared especially keeping the applied statisticians in mind, emphasizing applications-oriented methods and techniques, including references to appropriate software when relevant.· Contributors are internationally renowned experts in their respective areas· Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research· Methods for assessing Biomarkers, analysis of competing risks· Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs· Structural equations modelling and longitudinal data analysis



Small Clinical Trials


Small Clinical Trials
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-02-01

Small Clinical Trials written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-02-01 with Medical categories.


Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.