Sourcebook Of Models For Biomedical Research
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Sourcebook Of Models For Biomedical Research
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Author : P. Michael Conn
language : en
Publisher: Springer Science & Business Media
Release Date : 2008
Sourcebook Of Models For Biomedical Research written by P. Michael Conn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.
Biomedical Models And Resources
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1998-02-16
Biomedical Models And Resources written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-02-16 with Science categories.
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Models For Biomedical Research
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Author : National Research Council Staff
language : en
Publisher:
Release Date :
Models For Biomedical Research written by National Research Council Staff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Animal Models For Biomedical Research
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Author :
language : en
Publisher:
Release Date : 1969
Animal Models For Biomedical Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with categories.
Animal Models For Biomedical Research
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Author :
language : en
Publisher:
Release Date : 1970
Animal Models For Biomedical Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Animal models in research categories.
Models For Biomedical Research
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Author : National Research Council (U.S.). Committee on Models for Biomedical Research
language : en
Publisher: National Academies
Release Date : 1985
Models For Biomedical Research written by National Research Council (U.S.). Committee on Models for Biomedical Research and has been published by National Academies this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Animal experimentation categories.
Model Systems In Biology
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Author : Georg Striedter
language : en
Publisher: MIT Press
Release Date : 2022-08-23
Model Systems In Biology written by Georg Striedter and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-23 with Science categories.
How biomedical research using various animal species and in vitro cellular systems has resulted in both major successes and translational failure. In Model Systems in Biology, comparative neurobiologist Georg Striedter examines how biomedical researchers have used animal species and in vitro cellular systems to understand and develop treatments for human diseases ranging from cancer and polio to Alzheimer’s disease and schizophrenia. Although there have been some major successes, much of this “translational” research on model systems has failed to generalize to humans. Striedter explores the history of such research, focusing on the models used and considering the question of model selection from a variety of perspectives—the philosophical, the historical, and that of practicing biologists. Striedter reviews some philosophical concepts and ethical issues, including concerns over animal suffering and the compromises that result. He traces the history of the most widely used animal and in vitro models, describing how they compete with one another in a changing ecosystem of models. He examines how therapies for bacterial and viral infections, cancer, cardiovascular diseases, and neurological disorders have been developed using animal and cell culture models—and how research into these diseases has both taken advantage of and been hindered by model system differences. Finally, Striedter argues for a “big tent” biology, in which a diverse set of models and research strategies can coexist productively.
Advancing Disease Modeling In Animal Based Research In Support Of Precision Medicine
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2018-06-29
Advancing Disease Modeling In Animal Based Research In Support Of Precision Medicine written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-29 with Science categories.
Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop.
Research In The Biomedical Sciences
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Author : Michael Williams
language : en
Publisher: Academic Press
Release Date : 2017-10-20
Research In The Biomedical Sciences written by Michael Williams and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-20 with Science categories.
Research in the Biomedical Sciences: Transparent and Reproducible documents the widespread concerns related to reproducibility in biomedical research and provides a best practices guide to effective and transparent hypothesis generation, experimental design, reagent standardization (including validation and authentication), statistical analysis, and data reporting. The book addresses issues in the perceived value of the existing peer review process and calls for the need for improved transparency in data reporting. It reflects new guidelines for publication that include manuscript checklists, replication/reproducibility initiatives, and the potential consequences for the biomedical research community and societal health and well-being if training, mentoring, and funding of new generations of researchers and incentives for publications are not improved. This book offers real world examples, insights, and solutions to provide a thought-provoking and timely resource for all those learning about, or engaged in, performing and supervising research across the biomedical sciences. Provides a “big picture perspective on the scope of reproducibility issues and covers initiatives that have potential as effective solutions Offers real-world research context for transparent, reproducible experimental design, execution and reporting of biomedical research with the potential to address aspects of the translational gap in drug discovery Highlights the importance of reproducibility and the necessary changes in biomedical and pharmaceutical research training and incentives to ensure sustainability
Invertebrate Models For Biomedical Research
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Author : Springer
language : en
Publisher:
Release Date : 2014-01-15
Invertebrate Models For Biomedical Research written by Springer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.