Receptor Binding Radiotracers
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Receptor Binding Radiotracers
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Author : William C. Eckelman
language : en
Publisher: CRC Press
Release Date : 2019-07-17
Receptor Binding Radiotracers written by William C. Eckelman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-17 with Medical categories.
First Published in 1982, this book explores the role of receptor-binding radiotracers. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of radiology, and other practitioners in their respective fields.
Receptor Binding Radiotracers 1982
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Author : William C. Eckelman
language : en
Publisher: CRC Press
Release Date : 2017-11-22
Receptor Binding Radiotracers 1982 written by William C. Eckelman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Medical categories.
This series of books on Radiotracers in Biology and Medicine is on the one hand an unbelievably expansive enterprise and on the other hand, a most noble one as well. Tools to probe biology have developed at an accelerating rate. Hevesy pioneered the application of radioisotopes to the study of chemical processes, and since that time radioisotopic methodology has probably contributed as much as any other methodology to the analysis of the fine structure of biologic systems. Radioisotopic methodologies represent powerful tools for the determination of virtually any process of biologic interest. It should not be surprising, therefore, that any effort to encompass all aspects of radiotracer methodology is both desirable in the extreme and doomed to at least some degree of inherent failure. The current series is assuredly a success relative to the breadth of topics which range from in depth treatise of fundamental science or abstract concepts to detailed and specific applications, such as those medicine or even to the extreme of the methodology for sacrifice of anaimals as part of a radiotracer distribution study.
Receptor Binding Radiotracers
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Author : William C. Eckelman
language : en
Publisher: CRC-Press
Release Date : 1982-03-23
Receptor Binding Radiotracers written by William C. Eckelman and has been published by CRC-Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982-03-23 with Medical categories.
Revival
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Author : Taylor & Francis Group
language : en
Publisher:
Release Date : 2018-12
Revival written by Taylor & Francis Group and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12 with categories.
Current Directions In Radiopharmaceutical Research And Development
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Author : Steven J. Mather
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Current Directions In Radiopharmaceutical Research And Development written by Steven J. Mather and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Radiophannaceutical research has recently undergone a major change in direction. In past years it has been concerned mainly with the development of perfusion tracers, the biodistribution of which reflect the regional blood flow to areas of major organs such as the heart and brain. However, a major new direction of interest now lies in the development of receptor-binding radio-tracers which can be used to perform in-vivo characterisation of diseased tissues and it is likely that much of the future research in this field will follow this direction. The difficulties in developing such tracers are considerable. The researcher must first identify a promising target for radiopharmaceutical development. High specific activity radioactive molecules must be designed and synthesised which will both bind to the target receptor with high affinity, and also have the physicochemical characteristics which will allow them to reach the target site in sufficient quantity while at the same time showing minimal uptake in non-target tissues. Thus the knowledge base required for radiophannaceutical development has now expanded beyond the limits of radiopharmaceutical chemistry to include aspects of biochemistry, molecular biology and conventional drug design. The portfolio of basic knowledge required to support current radiopharmaceutical development is changing and scientists working in this arena need to be trained in this regard. At the same time, the very latest developments in the field need to be communicated to the scientific community in order to stimulate the advancement of this exciting new direction of research.
Radiotracers In Drug Development
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Author : Graham Lappin
language : en
Publisher: CRC Press
Release Date : 2006-04-03
Radiotracers In Drug Development written by Graham Lappin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-03 with Medical categories.
Although there are numerous books on drug metabolism, Radiotracers in Drug Development is unique in explaining how radiotracers are used to elucidate a drug's absorption, distribution, metabolism, and excretion (ADME). Covering traditional and recent technologies and applications, the book takes a strong industrial approach, discussing the b
Biologic Applications Of Radiotracers
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Author : Howard J. Glenn
language : en
Publisher: CRC Press
Release Date : 2019-08-14
Biologic Applications Of Radiotracers written by Howard J. Glenn and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-14 with Medical categories.
First published in 1982: This present volume presents an excellent amount of animal Models in radiotracer investigations, describes the animal radiopharmacology laboratory, and discusses radiotracer distribution differences between species.
Radiotracer Studies Of Interfaces
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Author : G. Horanyi
language : en
Publisher: Elsevier
Release Date : 2004-09-18
Radiotracer Studies Of Interfaces written by G. Horanyi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09-18 with Technology & Engineering categories.
Radiotracer Studies of Interfaces presents a selection of examples illustrating the application of radiotracer studies for different types of interfaces. The value of radiotracer studies in fields such as food chemistry, corrosion of metals, neurochemistry, biology and catalysis is revealed. Separate chapters are devoted to the environmental problems connected with nuclear reactors and with the nuclear industry in general. The book also presents efforts to minimize and avoid the risk of radioactive contamination in the environment by describing new approaches to the problem. Demonstrates the use of radiotracers Contains a detailed discussion of double-layer phenomena Separate chapters are devoted to the most important branches of science where radiotracer study of interfacial phenomena plays an important role
Radiopharmaceuticals And Brain Pathophysiology Studied With Pet And Spect
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Author : M. Diksic
language : en
Publisher: CRC Press
Release Date : 1990-11-30
Radiopharmaceuticals And Brain Pathophysiology Studied With Pet And Spect written by M. Diksic and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-11-30 with Medical categories.
This book covers three major areas essential to in vivo biochemical studies with PET and SPECT: synthesis of radiopharmaceuticals, biological modeling, and clinical applications. The book emphasizes advances in the synthesis of radiopharmaceuticals used in PET and SPECT studies of brain flow and oxidatative metabolism, in addition to biological modeling. The most widely used 2-deoxyglucose/2-fluorodeoxyglucose models are discussed, as well as models used in the quantitation of brain receptors. Other topics include a possible model for converting 6-[18F] fluorodopa images into the quantitative rate of dopamine synthesis, evaluations of technetium- and iodine-labeled blood flow tracers, and possibilities for using SPECT to measure other pathophysiological variables. This book will be a valuable reference source to students and specialists interested in these in vivo measurements.
Handbook Of Radiopharmaceuticals
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Author : Michael R. Kilbourn
language : de
Publisher: John Wiley & Sons
Release Date : 2021-04-12
Handbook Of Radiopharmaceuticals written by Michael R. Kilbourn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-12 with Science categories.
The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.