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Receptor Binding Techniques


Receptor Binding Techniques
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Receptor Binding Techniques


Receptor Binding Techniques
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Author : Mary Keen
language : en
Publisher: Springer Science & Business Media
Release Date : 1999

Receptor Binding Techniques written by Mary Keen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.


This cutting-edge collection of step-by-step experimental protocols demonstrates



Receptor Binding Techniques


Receptor Binding Techniques
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Author : Anthony P. Davenport
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Receptor Binding Techniques written by Anthony P. Davenport and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.


A comprehensive collection of readily reproducible methods for studying receptors in silico, in vitro, and in vivo. These cutting-edge techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knockout mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan PCR. These book equips the researcher with techniques for exploring the unprecedented number of new receptor systems now emerging and the so-called "orphan" receptors whose activating ligand has not been identified.



Receptor Binding In Drug Research


Receptor Binding In Drug Research
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Author : Robert A. O'Brien
language : en
Publisher: CRC Press
Release Date : 2020-08-27

Receptor Binding In Drug Research written by Robert A. O'Brien and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-27 with Science categories.


This book describes the applications of receptor techniques in many different areas in addition to conventional drug and neurotransmitter binding sites. It reviews humoral modulators such as a leukotrienes, interferon, platelet-derived growth factor, and novel endogenous ligands.



Receptor Binding Radiotracers


Receptor Binding Radiotracers
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Author : William C. Eckelman
language : en
Publisher: CRC Press
Release Date : 2019-07-17

Receptor Binding Radiotracers written by William C. Eckelman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-17 with Medical categories.


First Published in 1982, this book explores the role of receptor-binding radiotracers. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of radiology, and other practitioners in their respective fields.



Steroid Receptor Methods


Steroid Receptor Methods
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Author : Benjamin A. Lieberman
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-08-10

Steroid Receptor Methods written by Benjamin A. Lieberman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-08-10 with Medical categories.


A distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA binding characteristics, hormone binding assays, and the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness.



Principles And Techniques Of Biochemistry And Molecular Biology


Principles And Techniques Of Biochemistry And Molecular Biology
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Author : Keith Wilson
language : en
Publisher: Cambridge University Press
Release Date : 2010-03-04

Principles And Techniques Of Biochemistry And Molecular Biology written by Keith Wilson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-04 with Medical categories.


Uniquely integrates the theory and practice of key experimental techniques for bioscience undergraduates. Now includes drug discovery and clinical biochemistry.



Thermodynamics And Kinetics Of Drug Binding


Thermodynamics And Kinetics Of Drug Binding
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Author : György Keserü
language : en
Publisher: John Wiley & Sons
Release Date : 2015-08-17

Thermodynamics And Kinetics Of Drug Binding written by György Keserü and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-17 with Medical categories.


This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.



Bioassay Methods In Natural Product Research And Drug Development


Bioassay Methods In Natural Product Research And Drug Development
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Author : Lars Bohlin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Bioassay Methods In Natural Product Research And Drug Development written by Lars Bohlin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Bioassay Methods in Natural Product Research and Drug Development contains the proceedings from the Phytochemical Society of Europe's very successful symposium on this topic, held August 24-27, 1997 in Uppsala, Sweden. In this volume, leading academic and industrial scientists discuss novel methods for assaying natural products to find new structure-activity relationships. Of key importance in this process is the availability and reliability of specific bioassay methods, but chapters also discuss chemical and biological diversity and how to dereplicate natural product extracts to increase efficiency in lead discovery. Anti-tumor, HIV-inhibitory, antiprotozoal, anti-infective and immunomodulatory natural products are discussed. Various industrial projects are presented for the first time. This volume bridges the gap between academic and industrial research and scientists, and should be required reading in drug companies and faculties of pharmacy, as well as serving scientists in pharmacognosy, pharmacology, phytochemistry, natural products and drug discovery.



Receptor Binding Techniques


Receptor Binding Techniques
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Author :
language : en
Publisher:
Release Date : 1980

Receptor Binding Techniques written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Binding sites (Biochemistry) categories.




Using Cns Autopsy Tissue In Psychiatric Research A Practical Guide


Using Cns Autopsy Tissue In Psychiatric Research A Practical Guide
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Author : Brian Dean
language : en
Publisher: CRC Press
Release Date : 2019-02-13

Using Cns Autopsy Tissue In Psychiatric Research A Practical Guide written by Brian Dean and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-13 with Medical categories.


Essential for the laboratory, this practical manual presents a wide variety of techniques associated with the use of human CNS tissue obtained at autopsy. The book contains detailed methodologies in discrete chapters written by an expert in the specific field. It also addresses the potential for extending molecular studies in brain tissue obtain