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Red Cell Development


Red Cell Development
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Red Cell Development


Red Cell Development
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Author : James Bieker
language : en
Publisher: Elsevier
Release Date : 2008-09-12

Red Cell Development written by James Bieker and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-12 with Science categories.


This compendium provides a concise and up-to-date assessment of critical recent issues related to erythroid biology. Developmental, epigenetic, methodological, biochemical, and clinical aspects are integrated to provide a powerful overview of their interrelationships and importance to the generation of the red cell. The excitement generated by these novel observations and the anticipation of future directions in studies of the red cell is a highlight of this volume. The first comprehensive volume covering the breadth of the topic The latest advancements that lead to novel directions in the study of red cells An informative discussion of red cells as they relate to the essential oxygen-carrying component of the body



The Red Blood Cell


The Red Blood Cell
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Author : Douglas MacN. Surgenor
language : en
Publisher:
Release Date : 1974

The Red Blood Cell written by Douglas MacN. Surgenor and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Erythrocytes categories.




Rossi S Principles Of Transfusion Medicine


Rossi S Principles Of Transfusion Medicine
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Author : Toby L. Simon
language : en
Publisher: John Wiley & Sons
Release Date : 2016-05-23

Rossi S Principles Of Transfusion Medicine written by Toby L. Simon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-23 with Medical categories.


Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available Led by a world class Editor team, including two past-presidents of AABB, a past- President of the American Board of Pathology and members of the FDA Blood Products Advisory Committee , and international contributor team Comprehensive reference resource, considered the gold standard in transfusion Covers current hot topics such as donor care – including the frequency of donation and management of iron deficiency/status), patient blood management, hemovigilance, cstem cell therapies, and global aspects of the organization of transfusion and transplant services New material on molecular immunohematology Companion website includes figures, full text and references



The Red Cell Life Cycle From Erythropoiesis To Clearance


The Red Cell Life Cycle From Erythropoiesis To Clearance
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Author : Lars Kaestner
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-05

The Red Cell Life Cycle From Erythropoiesis To Clearance written by Lars Kaestner and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-05 with categories.


The eBook ‘The red cell life-cycle from erythropoiesis to clearance’ continues the discussion of questions like: What are the changes associated with red blood cell maturation, adulthood and senescence? What are the determinants of red blood cell life span and clearance? What are the mechanisms in control of red blood cell mass in healthy humans and patients with various forms of anaemia? Can red blood cells be 'trained' to provide the body with more oxygen during endurance exercises? What are the markers of circulating red blood cell senescence and in cells during storage and transfusion? And what can be learned from various species that developed advanced adaptations to maintain oxygen delivery under stress conditions such as exercising to the limit, diving or living in anaerobic aquatic habitats or at high altitude? Within the approximately 120 days (or 40 in a mouse, or 150-170 in a horse) life span of 'healthy' red blood cells, many cellular properties change leading to aged mixed cell populations in the circulation. Red blood cells seem to be genetically terminated by the time they become red blood cells and the contributions of this eBook increase the understanding of this process. There are surprisingly versatile remodeling processes happening during the red blood cell life span. Numerous disorders are associated with the premature onset of the 'ageing process' of red blood cells. Furthermore, in vitro ageing and/or modifications as well as the slowing down of the modifications is an important issue in transfusion medicine. Many of the molecular mechanisms behind such effects are elucidated in this eBook.



Hematopoiesis


Hematopoiesis
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Author : Leonard I. Zon
language : en
Publisher: Oxford University Press
Release Date : 2001-04-12

Hematopoiesis written by Leonard I. Zon and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-04-12 with Medical categories.


Hematopoiesis, or the process of blood formation, has been extensively studied at both basic and clinical levels. Human diseases such as thalassemia, immunodeficiency, and leukemia represent defects in this process. Approaches to treat these disorders have required a basic understanding of the biology of blood cells. For instance, hemapoietic stem cell replacement or bone marrow transplantation has been used to ameliorate disease. This volume focuses on hematopoiesis at a cellular and molecular level, and establishes the basis for clinical manipulation of hematopoietic cells for therapeutic benefit. In Part I, the cellular characteristics of progenitors and stem cells are explored. Emphasis is placed on purification of stem cells and both in vitro and in vivo assays. The regulation of normal and leukemis stem cells is illustrated. An excellent discussion of potential use of these cells for gene therapy concludes this section. Hemapoiesis is easily studied during embryogenesis. Part II develops the concept of the waves of hemapoiesis during development. Comparative hematology is making a major comeback as a field in the 1990's. One hope is that general principles of hematopoiesis will be established by studying many models and systems. Part III delves into critical factors that regulate hematopoiesis, including both intracellular and extracellular signals. Part IV and V describe lineage programs for myeloid and lymphoid lineages. These chapters are meant to be illustrative of the different cell fates, but are not exhaustive. Part VI examines the genetics of hematopoisis, particularly in animal models. The hematopoietic system is in constant contact with stromal cells and endothelial cells during development and in the adult. Evidence suggests that endothelial cells and blood cells may arise from a common progenitor, the hemangioblast. Part VII and VIII discuss the stromal and endothelial cells with the emphasis on their interaction with hematopoietic cells.



Membrane Processes In Erythroid Development And Red Cell Life Time


Membrane Processes In Erythroid Development And Red Cell Life Time
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Author : Giampaolo Minetti
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-25

Membrane Processes In Erythroid Development And Red Cell Life Time written by Giampaolo Minetti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-25 with Science categories.




Hematopoietic Stem Cell Development


Hematopoietic Stem Cell Development
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Author : Isabelle Godin
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-05-27

Hematopoietic Stem Cell Development written by Isabelle Godin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-27 with Medical categories.


This book collects articles on the biology of hematopoietic stem cells during embryonic development, reporting on fly, fish, avian and mammalian models. The text invites a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing conserved trends in development. The book reviews current knowledge on human hematopoietic development and discusses recent breakthroughs of relevance to both researchers and clinicians.



Molecular Biology Of The Cell


Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.




Transcriptional And Epigenetic Mechanisms Regulating Normal And Aberrant Blood Cell Development


Transcriptional And Epigenetic Mechanisms Regulating Normal And Aberrant Blood Cell Development
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Author : Constanze Bonifer
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-12

Transcriptional And Epigenetic Mechanisms Regulating Normal And Aberrant Blood Cell Development written by Constanze Bonifer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-12 with Medical categories.


During vertebrate hematopoiesis many specialized cell types are formed with vastly different functions such as B cells, T cells, granulocytes, macrophages, erythrocytes and megakaryocytes. To tightly control the enormous proliferative potential of developing blood cells, an intricately balanced signaling and transcription network has evolved that ensures that the different cell types are formed at the right time and in the right numbers. Intricate regulatory mechanisms ensure that blood cells function properly and have a determined life span. Moreover, in the adaptive immune system, long-lived memory cells have evolved that ensure that when pathogens have been seen once they will never cause a problem again. In this book we will therefore make a journey from asking how more primitive organisms use the epigenetic regulatory machinery to balance growth with differentiation control towards digging deep into what controls the function of specialized cells of the human immune system. We will first discover that flies make blood but exist without blood vessels, why fish make blood cells in the kidney and which precise genetic circuitries are required for these developmental pathways. We will then learn the regulatory principles that drive the differentiation of mature blood cells from stem cells and what controls their function in mammals. In the process, we will find out what unites hematopoietic stem cells and endothelial cells. Finally, we will shed light on the molecular mechanisms that either alter hematopoietic cell differentiation or lead to the development of cells with impaired function.



Regulation Of Red Cell Life Span Erythropoiesis Senescence And Clearance


Regulation Of Red Cell Life Span Erythropoiesis Senescence And Clearance
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Author : Lars Kaestner
language : en
Publisher: Frontiers E-books
Release Date : 2014-12-03

Regulation Of Red Cell Life Span Erythropoiesis Senescence And Clearance written by Lars Kaestner and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-03 with Biology (General) categories.


Human red blood cells are formed mainly in the bone marrow and are believed to have an average life span of approximately 120 days. However, is it true for all red blood cells? What are the changes associated with red cell maturation, adulthood and senescence? What are the determinants of red cell life span and clearance? What are the mechanisms in control of red cell mass in healthy humans and patients with various forms of anemia? What are the markers of circulating red cell senescence and in cells during storage and transfusion? Within the life span may properties of red cells change leading to age-mixed circulating cell populations. Although these cells appear to be genetically terminated by the time they are released into the blood stream, they undergo surprisingly versatile modifications depending on the life-style and health conditions of a “human host”. Numerous disorders are believed to be associated with facilitated ageing of red blood cells. “In vitro ageing” and damage of red blood cells during storage is yet one more important issue related to the risks and efficiency of blood transfusion. Many of the mechanisms behind such effects are far from being fully understood. In this context the Research Topic is set to include articles in the field of biochemical investigations, biophysical approaches, physiological and clinical studies related to red blood cell maturation and aging. This includes Original Research, Methods, Hypothesis and Theory, Reviews and Perspectives.