[PDF] Regulating With Rna In Bacteria And Archaea - eBooks Review

Regulating With Rna In Bacteria And Archaea


Regulating With Rna In Bacteria And Archaea
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Regulating With Rna In Bacteria And Archaea


Regulating With Rna In Bacteria And Archaea
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Author : Gisela Storz
language : en
Publisher: John Wiley & Sons
Release Date : 2020-07-10

Regulating With Rna In Bacteria And Archaea written by Gisela Storz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-10 with Medical categories.


Revealing the many roles of RNA in regulating gene expression For decades after the discoveries of messenger RNA, transfer RNA, and ribosomal RNA, it was largely assumed that the role of RNA in the cell was limited to shuttling the genomic message, chaperoning amino acids, and toiling in the ribosomes. Eventually, hints that RNA molecules might have regulatory roles began to appear. With the advent of genomics and bioinformatics, it became evident that numerous other RNA forms exist and have specific functions, including small RNAs (sRNA), RNA thermometers, and riboswitches to regulate core metabolic pathways, bacterial pathogenesis, iron homeostasis, quorum sensing, and biofilm formation. All of these functions, and more, are presented in Regulating with RNA in Bacteria and Archaea, written by RNA biologists from around the globe. Divided into eight sections-RNases and Helicases, Cis-Acting RNAs, Cis Encoded Base Pairing RNAs, Trans-Encoded Base Pairing RNAs, Protein Titration and Scaffolding, General Considerations, Emerging Topics, and Resources-this book serves as an excellent resource for established RNA biologists and for the many scientists who are studying regulated cellular systems. It is no longer a fair assumption that gene expression regulation is the provenance of proteins only or that control is exerted primarily at the level of transcription. This book makes clear that regulatory RNAs are key partners along with proteins in controlling the complex interactions and pathways found within prokaryotes.



Rna Turnover In Bacteria Archaea And Organelles


Rna Turnover In Bacteria Archaea And Organelles
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Author : Lynne E. Maquat
language : en
Publisher: Academic Press
Release Date : 2008-12-23

Rna Turnover In Bacteria Archaea And Organelles written by Lynne E. Maquat and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-23 with Science categories.


Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements, responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. Covers the difference in processing of mRNA between eukaryotes, bacteria and archea. Benefit: Processing of mRNA differs greatly between eukaryotes, bacteria and archea and this affords researchers readily reproducible techniques to understand and study the molecular pathogenesis of disease Expert researchers introduce the most advanced technologies and techniques to identify mRNA processing, transport, localization and turnover which are central to the process of gene expression. Benefit: Keeps MIE buyers and online subscribers up-to-date with the latest research Offers step by step lab instructions including necessary equipment and reagents. Benefit: Provides tried and tested techniques which eliminate searching through many different sources. Tested techniques are trustworthy and avoid pitfalls so the same mistakes are not made over and over



Rna Metabolism And Gene Expression In Archaea


Rna Metabolism And Gene Expression In Archaea
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Author : Béatrice Clouet-d'Orval
language : en
Publisher: Springer
Release Date : 2017-10-28

Rna Metabolism And Gene Expression In Archaea written by Béatrice Clouet-d'Orval and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-28 with Science categories.


This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications of gene expression, it presents the current state of knowledge on archaeal RNA biology in 13 chapters. Topics covered include the modification and maturation of RNAs, the function of small non-coding RNAs and the CRISPR-Cas defense system. While Archaea have long been considered exotic microbial extremophiles, they are now increasingly being recognized as important model microorganisms for the study of molecular mechanisms conserved across the three domains of life, and with regard to the relevance of similarities and differences to eukaryotes and bacteria. This unique book offers a valuable resource for all readers interested in the regulation of gene expression in Archaea and RNA metabolism in general.



Bacterial Regulatory Rna


Bacterial Regulatory Rna
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Author : Véronique Arluison
language : en
Publisher: Springer Nature
Release Date : 2024-01-13

Bacterial Regulatory Rna written by Véronique Arluison and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-13 with Science categories.


This second edition details new and updated methods used for studying prokaryotic non-coding RNAs and their protein accomplices. Chapters detail discovery of ncRNAs, characterization of their structure, functions, and their interactomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacterial Regulatory RNA: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.



Evolution Of Structure And Function Of Kink Turn Containing Rnas In The Domain Archaea


Evolution Of Structure And Function Of Kink Turn Containing Rnas In The Domain Archaea
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Author :
language : en
Publisher:
Release Date : 2015

Evolution Of Structure And Function Of Kink Turn Containing Rnas In The Domain Archaea written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.


The Domain Archaea is comprised of prokaryotic organisms known for often living in extreme environments. Despite potential biotechnological uses and their importance to the carbon and nitrogen cycles, archaea are understudied compared to eukaryotes and bacteria. Considering that archaea share features of bacterial RNA regulation (e.g., CRISPRs) and have transcription and translation machinery similar to eukaryotes, elucidating mechanisms of archaeal RNA biology may help us understand the evolution of RNA in the tree of life. For my dissertation I studied archaeal RNAs that contain the kink-turn, an RNA structural motif, with an emphasis on C/D box sRNAs and H/ACA box sRNAs.



The Regulation Of Stable Rna In Bacteria


The Regulation Of Stable Rna In Bacteria
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Author : Marshal Taylor Swanton
language : en
Publisher:
Release Date : 1973

The Regulation Of Stable Rna In Bacteria written by Marshal Taylor Swanton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with categories.




Stress And Environmental Regulation Of Gene Expression And Adaptation In Bacteria


Stress And Environmental Regulation Of Gene Expression And Adaptation In Bacteria
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Author : Frans J. de Bruijn
language : en
Publisher: John Wiley & Sons
Release Date : 2016-07-13

Stress And Environmental Regulation Of Gene Expression And Adaptation In Bacteria written by Frans J. de Bruijn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-13 with Science categories.


Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the stringent response, efflux pumps, alarmones, and modulation of the cell envelope or membranes, to name a few. Many regulatory elements are conserved in different bacteria; however there are endless variations on the theme and novel elements of gene regulation in bacteria inhabiting particular environments are constantly being discovered. Especially in (pathogenic) bacteria colonizing the human body a plethora of bacterial responses to innate stresses such as pH, reactive nitrogen and oxygen species and antibiotic stress are being described. An attempt is made to not only cover model systems but give a broad overview of the stress-responsive regulatory systems in a variety of bacteria, including medically important bacteria, where elucidation of certain aspects of these systems could lead to treatment strategies of the pathogens. Many of the regulatory systems being uncovered are specific, but there is also considerable “cross-talk” between different circuits. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria is a comprehensive two-volume work bringing together both review and original research articles on key topics in stress and environmental control of gene expression in bacteria. Volume One contains key overview chapters, as well as content on one/two/three component regulatory systems and stress responses, sigma factors and stress responses, small non-coding RNAs and stress responses, toxin-antitoxin systems and stress responses, stringent response to stress, responses to UV irradiation, SOS and double stranded systems repair systems and stress, adaptation to both oxidative and osmotic stress, and desiccation tolerance and drought stress. Volume Two covers heat shock responses, chaperonins and stress, cold shock responses, adaptation to acid stress, nitrosative stress, and envelope stress, as well as iron homeostasis, metal resistance, quorum sensing, chemotaxis and biofilm formation, and viable but not culturable (VBNC) cells. Covering the full breadth of current stress and environmental control of gene expression studies and expanding it towards future advances in the field, these two volumes are a one-stop reference for (non) medical molecular geneticists interested in gene regulation under stress.



Rna Infrastructure And Networks


Rna Infrastructure And Networks
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Author : Lesley J. Collins
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-15

Rna Infrastructure And Networks written by Lesley J. Collins and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-15 with Medical categories.


RNAs form complexes with proteins and other RNAs. The RNA‐infrastructure represents the spatiotemporal interaction of these proteins and RNAs in a cell‐wide network. RNA Infrastructure and Networks brings together these ideas to illustrate the scope of RNA‐based biology, and how connecting RNA mechanisms is a powerful tool to investigate regulatory pathways. This book is but a taste of the wide range of RNA‐based mechanisms that connect in the RNA infrastructure.



Rna Based Regulation In Human Health And Disease


Rna Based Regulation In Human Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-08-19

Rna Based Regulation In Human Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Medical categories.


RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic Features contributions from leading experts in the field



Computational Methods For Understanding Bacterial And Archaeal Genomes


Computational Methods For Understanding Bacterial And Archaeal Genomes
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Author : Ying Xu
language : en
Publisher: World Scientific
Release Date : 2008

Computational Methods For Understanding Bacterial And Archaeal Genomes written by Ying Xu and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.


Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.