Regulation Of Synaptic Structure And Function

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Regulation Of Synaptic Structure And Function

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Author : Zhiyong Shao
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-18

Regulation Of Synaptic Structure And Function written by Zhiyong Shao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-18 with Science categories.

Imaging Synapse Structure And Function

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Author : George J. Augustine
language : en
Publisher: Frontiers Media SA
Release Date : 2017-07-06

Imaging Synapse Structure And Function written by George J. Augustine and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-06 with categories.

Development of new imaging technologies in recent years has transformed neuroscience in profound ways. Following on the heels of the revolution based on the Green Fluorescent Protein, refined genetically-encoded fluorescent reporters and genetic targeting strategies now enable optical recording of synaptic transmission in defined neuronal populations at speeds approaching the enviable temporal resolution of electrophysiology. Super-resolution light microscopy permits observation of synapses and their molecular machinery at sub-diffraction resolution. At the ultrastructural level, automated forms of electron microscopy, improvements in specimen fixation methods, and recent efforts to correlate data from light and electron micrographs now make the reconstruction of functional neural circuits a reality. Finally, the use of optogenetic actuators, such as channelrhodopsins, allows precise temporal and spatial manipulation of neuronal activity and is revealing profound insights into the organization of neural circuits and their roles in behavior. This research topic highlights recent advances in both light and electron microscopy, with a specific focus on approaches that combine innovations from several different fields to obtain novel information about synapse structure and function. We are confident that this collection of articles - three original research papers, six reviews, one methods paper and one perspective article - will enable neuroscientists to achieve the next generation of experiments aimed at cracking the neural code.

Structural And Functional Organization Of The Synapse

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Author : Johannes W. Hell
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-06-25

Structural And Functional Organization Of The Synapse written by Johannes W. Hell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-25 with Medical categories.

This new Springer volume, which comes complete with a free DVD, is a comprehensive and detailed overview of the synapse with emphasis on the glutamatergic synapse. Most chapters relate the synapse’s functional aspects to its molecular mechanisms. This approach shows which mechanisms are characterized on both the functional and structural level and can thus be considered firmly established. It’s an important text for neuroscientists and disease-oriented clinicians in neurology.

Regulatory Rnas

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Author : Bibekanand Mallick
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-01

Regulatory Rnas written by Bibekanand Mallick and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-01 with Science categories.

Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discovering non-coding RNAs (ncRNAs) which spans through a major portion of the genome. These RNAs most often act as riboregulators, and actively participate in the regulation of important cellular functions at the transcriptional and/or post-transcriptional levels rather than simply being an intermediated messenger between DNA and proteins. As the appreciation for the importance of ncRNAs continues to emerge, it is also increasingly clear that these play critical roles in gene regulatory processes during development and differentiation. Further, regulatory RNAs are useful biomarkers for diagnosis of diseases. Hence these RNA regulators are essential to the development of therapeutics. This book on “Regulatory RNAs” offers a comprehensive view on our current understanding of these regulatory RNAs viz. siRNA, miRNA, piRNA, snoRNA, long non-coding RNA, small RNA etc. It addresses both the biogenesis and mechanism of action of regulatory RNAs with a primary focus on their annotation, experimental methodologies (microarray, next-gen sequencing etc.) for their discovery, computational tools for their prediction, and above all, applications of these revolutionary regulatory molecules in understanding biological systems and diseases, including therapeutics. This comprehensive volume is intended for readers with research or teaching interests in ncRNA biology and will provide a major information resource on current research in the fast-moving fields of RNA and gene expression regulation. Cutting-edge and concise, “Regulatory RNAs: Basics, Methods and Applications” promises to support vital research in the field of regulatory RNAs, ever-continuing to grow rapidly and gain increasing importance in basic and translational biology.

Rna Regulation In Development And Disease

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Author : Maritza Jaramillo
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-15

Rna Regulation In Development And Disease written by Maritza Jaramillo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-15 with categories.

Biomedical Index To Phs Supported Research Pt A Subject Access A H

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Author :
language : en
Publisher:
Release Date : 1992

Biomedical Index To Phs Supported Research Pt A Subject Access A H written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medicine categories.

Neurochemical Mechanisms In Disease

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Author : John P. Blass
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-01

Neurochemical Mechanisms In Disease written by John P. Blass and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-01 with Medical categories.

This newest volume of Advances in Neurobiology deals with the Neurochemistry of disease, with chapters covering both human diseases and animal “model” diseases.

Biomedical Index To Phs Supported Research

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Author :
language : en
Publisher:
Release Date : 1991

Biomedical Index To Phs Supported Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medicine categories.

Drosophila A Versatile Model For Molecular Physiological And Behavioral Studies

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Author : Gabriella Mazzotta
language : en
Publisher: Frontiers Media SA
Release Date : 2021-04-01

Drosophila A Versatile Model For Molecular Physiological And Behavioral Studies written by Gabriella Mazzotta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-01 with Science categories.

Research Awards Index

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Author :
language : en
Publisher:
Release Date : 1989

Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medicine categories.