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Regulators And Effectors Of Small Gtpases

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Regulators And Effectors Of Small Gtpases Part G Ras Family Ii

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Author :
language : en
Publisher: Elsevier
Release Date : 2001-06-05

Regulators And Effectors Of Small Gtpases Part G Ras Family Ii written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-05 with Science categories.

The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences.This volume and its companions (Volumes 255, 256, 257, and the forthcoming 325, 329, and 332) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in the above-mentioned aspects of cell biology at the molecular level.

Regulators And Effectors Of Small Gtpases Part E Gtpases Involved In Vesicular Traffic

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Author :
language : en
Publisher: Elsevier
Release Date : 2001-02-08

Regulators And Effectors Of Small Gtpases Part E Gtpases Involved In Vesicular Traffic written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-02-08 with Medical categories.

Small GTPases play a key role in many aspects of contemporary cell biology: control of cell growth and differentiation; regulation of cell adhesion and cell movement; the organization of the actin cytoskeleton; and the regulation of intracellular vesicular transport. This volume and its companions (Volumes 255, 256, 257, and the forthcoming 325) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.

Regulators And Effectors Of Small Gtpases Rho Family

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Author :
language : en
Publisher: Elsevier
Release Date : 2006-02-21

Regulators And Effectors Of Small Gtpases Rho Family written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-21 with Science categories.

The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continually increasing, functionally complex array of downstream effectors. Since the last Methods in Enzymology volume on this topic in 2000, Rho GTPases have continued to receive a huge amount of attention. The human genome sequence has revealed the full extent of the Rho GEF and Rho GAP families (over 80 members for each) and the challenge of identifying the molecular interactions and cellular pathways influenced by each of these regulators is a daunting prospect. This new volume, Regulators and Effectors of Small GTPases: Rho Family, describes some of the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular level. Describes the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular levels Includes new imaging techniques that revolutionize the ability to visualize GTPase activities Over 150 international contributors

Regulators And Effectors Of Small Gtpases Part D Rho Family

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Author :
language : en
Publisher: Elsevier
Release Date : 2000-10-11

Regulators And Effectors Of Small Gtpases Part D Rho Family written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-10-11 with Medical categories.

This volume and its companions (Volumes 255, 256, 257, and the forthcoming 329) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Regulators And Effectors Of Small Gtpases Ras Family

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Author :
language : en
Publisher: Elsevier
Release Date : 2006-06-07

Regulators And Effectors Of Small Gtpases Ras Family written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-07 with Science categories.

The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continually increasing, functionally complex array of downstream effectors. Since the last Methods in Enzymology volume on this topic in 2000, the study of Ras Family GTPases has witnessed a plethora of new directions and trends. With regards to the founding member of the Ras superfamily, the study of Ras in oncogenesis has seen the development and application of more advanced model cell culture and animal systems. The discovery of mutationally activated B-Raf in human cancers has injected renewed interest in this classical effector pathway of Ras. Includes a database for Ras family proteins and their effectors and regulators Complimentary to volume 406 coverage of the Rho family Over 150 international contributors