Regulators And Effectors Of Small Gtpases Ras Family
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Regulators And Effectors Of Small Gtpases Ras Family
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Author :
language : en
Publisher: Elsevier
Release Date : 2006-06-07
Regulators And Effectors Of Small Gtpases Ras Family written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-07 with Science categories.
The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continually increasing, functionally complex array of downstream effectors. Since the last Methods in Enzymology volume on this topic in 2000, the study of Ras Family GTPases has witnessed a plethora of new directions and trends. With regards to the founding member of the Ras superfamily, the study of Ras in oncogenesis has seen the development and application of more advanced model cell culture and animal systems. The discovery of mutationally activated B-Raf in human cancers has injected renewed interest in this classical effector pathway of Ras. - Includes a database for Ras family proteins and their effectors and regulators - Complimentary to volume 406 coverage of the Rho family - Over 150 international contributors
Regulators And Effectors Of Small Gtpases Part E Gtpases Involved In Vesicular Traffic
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Author :
language : en
Publisher: Academic Press
Release Date : 2001-02-08
Regulators And Effectors Of Small Gtpases Part E Gtpases Involved In Vesicular Traffic written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-02-08 with Science categories.
Small GTPases play a key role in many aspects of contemporary cell biology: control of cell growth and differentiation; regulation of cell adhesion and cell movement; the organization of the actin cytoskeleton; and the regulation of intracellular vesicular transport. This volume and its companions (Volumes 255, 256, 257, and the forthcoming 325) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.
Regulators And Effectors Of Small Gtpases Part G Ras Family Ii
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Author :
language : en
Publisher: Elsevier
Release Date : 2001-06-05
Regulators And Effectors Of Small Gtpases Part G Ras Family Ii written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-05 with Science categories.
The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences.This volume and its companions (Volumes 255, 256, 257, and the forthcoming 325, 329, and 332) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in the above-mentioned aspects of cell biology at the molecular level.
Regulators And Effectors Of Small Gtpases Part F Ras Family I
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Author :
language : en
Publisher: Elsevier
Release Date : 2001-04-17
Regulators And Effectors Of Small Gtpases Part F Ras Family I written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-04-17 with Science categories.
The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today, truly an essential publication for researchers in all fields of life sciences.This volume and its companions (Volumes 255, 256, 257, and the forthcoming 325 and 329) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.
Lipidomics And Bioactive Lipids Specialized Analytical Methods And Lipids In Disease
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Author :
language : en
Publisher: Elsevier
Release Date : 2007-11-09
Lipidomics And Bioactive Lipids Specialized Analytical Methods And Lipids In Disease written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-09 with Science categories.
This volume in the well-established Methods in Enzymology series features methods for the study of lipids using mass spectrometry techniques. Articles in this volume cover topics such as Liquid chromatography mass spectrometry for quantifying plasma lysophospholipids: potential biomarkers for cancer diagnosis; Measurement of eicosanoids in cancer tissues; Noninvasive Assessment of the Role of Cyclooxygenases in Cardiovascular HealthA Detailed HPLC/MS/MS Method; Lipidomics in Diabetes and the Metabolic Syndrome; LC-MS-MS Analysis of Neutral Eicosanoids; Quantification Of F2-Isoprostanes In Biological Fluids And Tissues As A Measure Of Oxidant Stress; Measurement of Products of Docosahexaenoic Acid Peroxidation, Neuroprostanes, and Neurofurans; Enantiomeric separation of hydroxy and hydroperoxy eicosanoids by chiral column chromatography; Targeted Chiral Lipidomics Analysis by Liquid Chromatography Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry (LC-ECAPCI/MS); Shotgun Lipidomics by Tandem Mass Spectrometry under Data-Dependent Acquisition Control; Identification of Intact Lipid Peroxides by Ag+ Coordination Ionspray Mass Spectrometry (CIS-MS); Quantification of Cardiolipin by Liquid Chromatography Electrospray Ionization Mass Spectrometry.
G Protein Pathways
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Author : Ravi Iyengar
language : en
Publisher: Academic Press
Release Date : 2002
G Protein Pathways written by Ravi Iyengar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cell receptors categories.
This third volume in the trio covering G proteins, features integrated approaches to studying G proteins. Methods pertaining to signaling mechanisms are presented, including theoretical and modeling approaches, biochemistry and molecular biology, and cell biology and physiology. The techniques for studying the structure and function of G proteins are important not only to those with specific research interests in them, but also endocrinologists and pharmacologists conducting research on signaling mechanisms that are increasingly understood to interact with G proteins.
Amyloid Prions And Other Protein Aggregates Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2006-10-06
Amyloid Prions And Other Protein Aggregates Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-06 with Science categories.
The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part C (volume 413) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies. - Presents detailed protocols - Includes troubleshooting tips - Provides coverage on structural biology, computational methods, and biology
Cytochrome P450
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Author : Eric F. Johnson
language : en
Publisher: Academic Press
Release Date : 2002
Cytochrome P450 written by Eric F. Johnson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Biochemistry categories.
Human genomics and genetics; Structure and mechanism; Regulation of expression; Metabolism; Invertebrate P450s.
Hyperthermophilic Enzymes
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Author : Michael W. W. Adams
language : en
Publisher: Academic Press
Release Date : 2001
Hyperthermophilic Enzymes written by Michael W. W. Adams and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Adaptation (Physiology) categories.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences. This volume and its companions (Volumes 330 and 331) cover all current knowledge concerning hyperthermophilic enzymes. Major topics in this volume include redox and thiol-dependent proteins, nucleic acid modifying enzymes, and protein stability from biochemical and biophysical standpoints.
Chromatin And Chromatin Remodeling Enzymes Part C
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Author : Carl Wu
language : en
Publisher: Elsevier
Release Date : 2004-04-07
Chromatin And Chromatin Remodeling Enzymes Part C written by Carl Wu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-07 with Science categories.
DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the chromatin remodelling enzymes play an important role in gene transcription. - Genetic assays of chromatin modification and remodeling - Histone modifying enzymes - ATP-dependent chromatin remodeling enzymes