Regulatory B Cells
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Insights Into Regulatory B Cells
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Author : Yiwei Chu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-09
Insights Into Regulatory B Cells written by Yiwei Chu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-09 with Medical categories.
Regulatory B Cells
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Author : Gaetano Vitale
language : en
Publisher:
Release Date : 2014
Regulatory B Cells written by Gaetano Vitale and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with B cells categories.
Annotation Regulatory B Cells: Methods and Protocols present the current experimental set-ups and methodologies useful for the identification and characterization of B cells with suppressive functions and for the study of their biological and immunological properties. Organized into four sections, this detailed volume covers the basic methods for the isolation and immunophenotypical characterization of specific B cell subsets from mouse and human tissues, methods for the investigation of the mechanisms of immune suppression operated by B cells, several experimental approaches for the ex vivo generation/expansion of IL-10-producing B cells, as well as procedures for the study of the immune suppressive function of B cells in specific pathological settings. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Regulatory B Cells: Methods and Protocols serves as an ideal guide for immunologists as well as for cell and molecular biologists interested in the intricacies of B cell biology.
Mechanisms Of Lymphocyte Activation And Immune Regulation Xi
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Author : Sudhir Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-21
Mechanisms Of Lymphocyte Activation And Immune Regulation Xi written by Sudhir Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-21 with Medical categories.
In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.
B Cells In Inflammatory And Neurodegenerative Diseases Of The Central Nervous System
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Author : Francesca Gilli
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-15
B Cells In Inflammatory And Neurodegenerative Diseases Of The Central Nervous System written by Francesca Gilli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-15 with Medical categories.
B Cells In Immunity And Tolerance
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Author : Ji-Yang Wang
language : en
Publisher: Springer Nature
Release Date : 2020-04-22
B Cells In Immunity And Tolerance written by Ji-Yang Wang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-22 with Medical categories.
This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.
Molecular Biology Of B Cells
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Author : Tasuku Honjo
language : en
Publisher: Elsevier
Release Date : 2014-10-09
Molecular Biology Of B Cells written by Tasuku Honjo and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-09 with Science categories.
Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response
The B Side Of B Cells
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Author : Maria Manuela Rosado
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-21
The B Side Of B Cells written by Maria Manuela Rosado and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-21 with Medical categories.
Human B Cell Populations
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Author : M. Ferrarini
language : en
Publisher: S Karger Ag
Release Date : 1997
Human B Cell Populations written by M. Ferrarini and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
B cells used to be considered as a homogeneous population of cells destined to produce antibodies of increasing affinity and to maintain an immunological memory. In recent years, it has been determined that B cells can be subdivided into different subsets characterized by distinct morphologic, phenotypic, and functional features. Presenting results of research work on the definition of B cell subset populations, this book explains the basic mechanisms that control B cell activation, stimulation and regulation. Articles include studies on both normal and malignant B cells and describe the mechanisms underlying T-B cell interactions during the immune response. The most important advances in the field of immunodeficiency are also reported. This volume will be essential not only for basic and clinical immunologists, but also for hematologists, pathologists and rheumatologists with a special interest in the pathogenesis of lymphoproliferative or autoimmune disorders.
T Cell Dependent And Independent B Cell Activation
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Author : E. Charles Snow
language : en
Publisher: CRC Press
Release Date : 1990-12-19
T Cell Dependent And Independent B Cell Activation written by E. Charles Snow and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-12-19 with Medical categories.
This book provides an analysis of the current subdisciplines comprising the study of humoral immune response. The first chapter presents a detailed discussion regarding the experimental and conceptual studies conducted prior to the mid-1970s that have served as a valuable research framework for investigators interested in the process by which B cells are activated following their exposure to antigens. Other chapters focus on topics such as membrane-associated proteins with important functional roles during B cell activation and differentiation; thymus-independent and thymus-dependent activation; mechanisms operative during B-T cell interactions, including the role of B cells as antigen-presenting cells; and the importance of soluble mediators. Additional topics include the regulatory role of T cells during B cell repertoire expression, memory development, tolerance, and autoimmunity. T-Cell Dependent and Independent B-Cell Activation is an important history and reference resource for humoral immune response investigators, as well as advanced graduate and medical students.
B Cell Trophic Factors And B Cell Antagonism In Autoimmune Disease
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Author : William Stohl
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2005-01-01
B Cell Trophic Factors And B Cell Antagonism In Autoimmune Disease written by William Stohl and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-01 with Medical categories.
The understanding of B cell biology has increased and expanded enormously in the last three decades. It is now known that B cells, in addition to just differentiating into antibody-secreting cells, serve many other vital functions. For example, their roles as antigen-presenting cells and cytokine-producing cells as well as effector cells and regulatory cells are well appreciated now. Indeed, the pathologic role of B cells in many autoimmune disorders may be largely autoantibody-independent. Today, the B cell is of considerable interest not only to immunologists but also to mainstream clinicians and scientists. The current volume covers the latest information on the functions of B cells in normal and disease states, and their therapeutic antagonism. Chapters cover cutting-edge topics from the basic to the clinical, including B cells in infection and autoimmunity, CD19-CD21 signal transduction complex, marginal zone B cell physiology and disease, B cell growth and differentiation, their role in rheumatoid arthritis, SLE treatment, the BAFF/APRIL system and B lymphocyte malignancies. This book is recommended reading for cellular and molecular immunologists as well as for rheumatologists, hematologists and clinical immunologists, and all those interested in human diseases in which B cells play an important contributory role.