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Regulatory Mechanisms In Transcriptional Signaling


Regulatory Mechanisms In Transcriptional Signaling
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Regulatory Mechanisms In Transcriptional Signaling


Regulatory Mechanisms In Transcriptional Signaling
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-07-25

Regulatory Mechanisms In Transcriptional Signaling written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-25 with Science categories.


Regulatory Mechanisms in Transcriptional Signaling, volume of Progress in Molecular Biology and Translational Science, includes in-depth discussion on roles of Chromatin remodeling proteins in nuclear receptor signaling, and the ANCCA regulator in cancer. This important resource, edited by Dr. Debabrata (Debu) Chakravarti, offers research on the progesterone receptor action in leiomyoma and endometrial cancer and emerging roles of the ubiquitin protein system in nuclear hormone receptor signaling to provide the reader with expert discussions of up-to-date research.



Mechanisms In Transcriptional Regulation


Mechanisms In Transcriptional Regulation
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Author : Albert J. Courey
language : en
Publisher: John Wiley & Sons
Release Date : 2009-01-22

Mechanisms In Transcriptional Regulation written by Albert J. Courey and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-22 with Science categories.


Mechanisms in Transcriptional Regulation provides a concisediscussion of the fundamental concepts in transcription and itsregulation. Covers RNA polymerases, transcriptional machinery, mechanismsof transcriptional activation, the histone code hypothesis, theepigenetic control of transcription, and combinatorial control insignaling and development Features over 80 figures available to download online Chapters include comprehensive reading lists, boxeshighlighting theoretical concepts and experimental methods andproblems designed to build and test understanding



Transcriptional Regulation Molecules Involved Mechanisms And Misregulation


Transcriptional Regulation Molecules Involved Mechanisms And Misregulation
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Author : Amelia Casamassimi
language : en
Publisher:
Release Date : 2019

Transcriptional Regulation Molecules Involved Mechanisms And Misregulation written by Amelia Casamassimi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Electronic books categories.


Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses.



Signalling Mechanisms From Transcription Factors To Oxidative Stress


Signalling Mechanisms From Transcription Factors To Oxidative Stress
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Author : Lester Packer
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Signalling Mechanisms From Transcription Factors To Oxidative Stress written by Lester Packer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.


A NATO Advanced Study Institute on "Molecular Mechanisms of Transcellular Signaling: from the Membrane to the Gene" was held on the Island of Spetsai, Greece, from August 15- 27, 1994. The aim of this Institute was to bring together researchers in the field of signal transduction mechanisms, transcription factors and gene regulation with those actively involved in studies on the implications of oxygen radicals and antioxidant defence mechanisms for cell function. As diverse as these fields may be, the emergence of their interconnection during the course of the Institute was an eye-opener for students and lecturers alike. 2 Presentations and discussions focussed on the role of Ca +, G-proteins, protein kinase C and phospholipases in signaling mechanisms. These broad principles were extended to transcription factors and gene regulation with an emphasis on the steroid hormone receptor superfamily and NFKB. Basic principles of free radical formation and antioxidant action (vitamin E and C) were presented and discussed in connection with effects on signaling pathways. This book present the content of the major lectures and a selection of the most relevant posters. These proceedings offer a comprehensive account of the most important topics discussed at the Institute. The book is intended to make the proceedings accessible to a large audience.



Molecular Biology Of The Cell


Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.




Post Transcriptional Mechanisms In Endocrine Regulation


Post Transcriptional Mechanisms In Endocrine Regulation
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Author : K.M.J. Menon, PhD
language : en
Publisher: Springer
Release Date : 2015-12-30

Post Transcriptional Mechanisms In Endocrine Regulation written by K.M.J. Menon, PhD and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-30 with Medical categories.


This book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms on disease and health are covered, providing a novel update to the scientific literature. Post-transcriptional regulatory mechanisms play an essential role in controlling dynamic gene expression. The outcome of this regulation includes control of the amount, timing, and location of protein expression. Regulation is mediated by cis-acting RNA sequences and structures and transacting RNA binding proteins and non-coding RNAs, including microRNAs. Recent advances in characterization of these regulatory factors have revealed enormous regulatory potential.



The Hormonal Control Of Gene Transcription


The Hormonal Control Of Gene Transcription
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Author : P. Cohen
language : en
Publisher: Elsevier
Release Date : 2012-12-02

The Hormonal Control Of Gene Transcription written by P. Cohen and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Over the past few years there have been considerable advances in our understanding of cellular control mechanisms, and current research is now linking areas of biology that were previously thought of as being quite separate. Molecular Aspects of Cellular Regulation is a series of occasional books on multidisciplinary topics which illustrate general principles of cellular regulation. Previous volumes described Recently Discovered Systems of Enzyme Regulation by Reversible Phosphorylation (Volumes 1 and 3), The Molecular Actions of Toxins and Viruses (Volume 2), Molecular Mechanisms of Transmembrane Signalling (Volume 4) and Calmodulin (Volume 5). This sixth volume, The Hormonal Control of Gene Transcription, has now been published to highlight recent important advances in our understanding of this topic which is linking two of the most active areas of current biochemical and molecular biological research (hormone action and gene transcription) and leading to the emergence of unifying concepts.



A Handbook Of Transcription Factors


A Handbook Of Transcription Factors
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Author : Timothy R. Hughes
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-10

A Handbook Of Transcription Factors written by Timothy R. Hughes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-10 with Medical categories.


Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.



Mechanisms Of Gene Regulation How Science Works


Mechanisms Of Gene Regulation How Science Works
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Author : Carsten Carlberg
language : en
Publisher: Springer Nature
Release Date : 2020-10-29

Mechanisms Of Gene Regulation How Science Works written by Carsten Carlberg and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-29 with Medical categories.


This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. Th is pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation.



Post Transcriptional Control Of Gene Expression In Plants


Post Transcriptional Control Of Gene Expression In Plants
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Author : Witold Filipowicz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Post Transcriptional Control Of Gene Expression In Plants written by Witold Filipowicz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


A recent volume of this series (Signals and Signal Transduction Pathways in Plants (K. Palme, ed.) Plant Molecular Biology 26, 1237-1679) described the relay races by which signals are transported in plants from the sites of stimuli to the gene expression machinery of the cell. Part of this machinery, the transcription apparatus, has been well studied in the last two decades, and many important mechanisms controlling gene expression at the transcriptional level have been elucidated. However, control of gene expression is by no means complete once the RNA has been produced. Important regulatory devices determine the maturation and usage of mRNA and the fate of its translation product. Post-transcriptional regulation is especially important for generating a fast response to environmental and intracellular signals. This book summarizes recent progress in the area of post-transcriptional regulation of gene expression in plants. 18 chapters of the book address problems of RNA processing and stability, regulation of translation, protein folding and degradation, as well as intracellular and cell-to-cell transport of proteins and nucleic acids. Several chapters are devoted to the processes taking place in plant organelles.