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Regulatory T Cells


Regulatory T Cells
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Signaling Mechanisms Regulating T Cell Diversity And Function


Signaling Mechanisms Regulating T Cell Diversity And Function
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Author : Taylor & Francis Group
language : en
Publisher: CRC Press
Release Date : 2021-03-30

Signaling Mechanisms Regulating T Cell Diversity And Function written by Taylor & Francis Group and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-30 with categories.


T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.



Eosinophils In Health And Disease


Eosinophils In Health And Disease
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Author : James J. Lee
language : en
Publisher: Elsevier
Release Date : 2012-12-31

Eosinophils In Health And Disease written by James J. Lee and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Medical categories.


Written and edited by leaders in the field, Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance. Despite an explosion of discovery in this area over the last decade, this is the only up-to-date resource on eosinophils and eosinophilia exists. This full-color volume provides an essential collection of world class information that is a must-have for any immunologist's workbench or bookshelf. - The only updated, comprehensive source of information on eosinophils on the market - Written by over 80 leaders in the field - Holistic view of the subject, including basic science, disease-specific chapters, therapeutic options and emerging areas of research



Translational Regenerative Medicine


Translational Regenerative Medicine
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Author : Anthony Atala
language : en
Publisher: Academic Press
Release Date : 2014-12-01

Translational Regenerative Medicine written by Anthony Atala and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-01 with Medical categories.


Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. - Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications - Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system - Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine



Neuroimmune Diseases


Neuroimmune Diseases
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Author : Hiroshi Mitoma
language : en
Publisher: Springer
Release Date : 2019-08-27

Neuroimmune Diseases written by Hiroshi Mitoma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-27 with Medical categories.


A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases



Chromatin Signaling And Diseases


Chromatin Signaling And Diseases
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Author : Olivier Binda
language : en
Publisher: Academic Press
Release Date : 2024-01-01

Chromatin Signaling And Diseases written by Olivier Binda and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-01 with Science categories.


Chromatin Signaling and Diseases, Second Edition, a volume in the Translational Epigenetics series, covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. Although human genome sequencing continues to improve, molecular mechanisms regulating gene expression remain largely misunderstood. Chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these, is considered in-depth in Chromatin Signaling and Diseases, Second Edition as well as the impact of gene expression defects associated with malfunctioning chromatin signaling. In addition, this new edition has been fully updated to address recent developments in the field, from phase separation of membrane-less organelles and local segregation of factors to chromatinisation of naked foreign DNA and cancer evolution as regulated by chromatin signaling.



Regulatory T Cells


Regulatory T Cells
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Author : Ling Lu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-26

Regulatory T Cells written by Ling Lu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-26 with Science categories.




Regulatory T Cells


Regulatory T Cells
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Author : Alexander Rudensky
language : en
Publisher: Academic Press
Release Date : 2011-12-06

Regulatory T Cells written by Alexander Rudensky and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-06 with Medical categories.


Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on regulatory T-cells. Contributions from leading authorities and industry experts Informs and updates on all the latest developments in the field



Regulatory T Cells And Clinical Application


Regulatory T Cells And Clinical Application
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Author : Shuiping Jiang
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-14

Regulatory T Cells And Clinical Application written by Shuiping Jiang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-14 with Medical categories.


Covering one of the hottest topics in immunology today, this book provides a comprehensive view of all types of regulatory T cells described so far in the literature. The book will have broad appeal to both researchers and clinicians.



Regulatory T Cells In Health And Disease


Regulatory T Cells In Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-11-26

Regulatory T Cells In Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-26 with Medical categories.


Regulatory T Cells in Health and Disease focuses on the mechanism by which T cells become regulatory T cells, the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer. - Contains contributions from leading authorities in the field of regulatory T cell biology - Informs and updates on all the latest developments in the field - Explores the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer



Regulatory T Cells And Autoimmune Diseases


Regulatory T Cells And Autoimmune Diseases
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Author : Mitesh Kumar Dwivedi
language : en
Publisher: Elsevier
Release Date : 2024-05-27

Regulatory T Cells And Autoimmune Diseases written by Mitesh Kumar Dwivedi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-27 with Medical categories.


Regulatory T cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic aspects. In particular, this book deals with the various Treg based mechanisms which can lead to autoimmune diseases and covers the different aspects of linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies. The book specifically focuses on the Treg based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood & blood vessel, and eye diseases and aims to provide a must-have reference for designing therapeutic strategies to treat these autoimmune diseases. Additionally, the book covers the vaccines induced effects on functioning of Tregs and development of CAR Tregs therapy for these autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. It is carefully designed to meet the requirements of both basic and advanced researchers in the area and give new dimensions and insight into the regulatory T cells' role in autoimmune disease pathogenesis and therapeutic aspects. - Brings the reader up-to-date on the mechanisms of regulatory T cells (Tregs) in pathogenesis and therapeutics of all autoimmune diseases known to date - Provides explicit color illustrations and comprehensible tables for explaining the mechanistic aspects and emerging information in the field - Includes human clinical trials and animal model studies for Tregs in diverse autoimmune diseases for the mitigation of the symptoms of autoimmune diseases - Offers scientifically applicable and relevant content for readers of various disciplines, including biomedical sciences, medical microbiology/biotechnology, immunology, and medicine