Report Of The Meeting To Review The Paediatric Antituberculosis Drug Optimization Priority List
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Report Of The Meeting To Review The Paediatric Antituberculosis Drug Optimization Priority List
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Author :
language : en
Publisher: World Health Organization
Release Date : 2021-03-25
Report Of The Meeting To Review The Paediatric Antituberculosis Drug Optimization Priority List written by and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-25 with Medical categories.
The Paediatric Antituberculosis Drug Optimization (PADO-TB) meetings provide a forum for clinicians, researchers, financial and technical partners and other relevant key stakeholders to work together, to ensure that priority optimal paediatric formulations of TB medicines are investigated, developed and made available to children in a timely manner. After the first meeting (PADO-TB1) in February 2019, WHO hosted an interim review of the PADO-TB1 priorities. The review considered the latest WHO recommendations and other relevant developments since February 2019, such as results of clinical trials, results of pharmacokinetics and pharmacodynamics studies, new formulations available and advancements of key drugs in the TB research and development pipeline. The 4.5-hour virtual review was attended by more than 50 experts including clinicians, researchers, representatives of national TB programmes (NTPs) from high TB burden countries, community representatives, financial and technical partners, members of the Child and Adolescent TB Working Group and representatives from various international agencies, including WHO. This report summarizes the main developments presented for various TB medicines and the decisions taken with regard to the PADO-TB priority list.
Paediatric Drug Optimization For Tuberculosis
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2024-05-30
Paediatric Drug Optimization For Tuberculosis written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-30 with Medical categories.
Paediatric drug optimization (PADO) exercises have been convened by the World Health Organization (WHO) for various diseases, demonstrating their potential and impact to accelerate access to optimal formulations in the context of fragmented small markets for medicines for children. The WHO Global Tuberculosis Programme has convened PADO-TB meetings since February 2019 (PADO-TB1), followed by an interim review of the PADO-TB1 priorities in September 2020. Optimization of paediatric TB medicines forms part of the key actions in the Roadmap towards ending TB in children and adolescents, third edition and contributes to the achievement of the targets for ending TB in children and adolescents set out at the second United Nations High-level Meeting on the Fight Against TB in 2023. Considering the latest WHO recommendations on drug-susceptible TB, drug-resistant TB and TB preventive treatment, recent developments in new TB medicines and formulations made available, results of clinical trials and studies, and advancements of key medicines in the TB R&D pipeline, WHO convened the second PADO-TB meeting (PADO-TB2) on 3–5 October 2023. This meeting report summarizes the proceedings, discussions and the main consensus-based outputs of the PADO-TB2 meeting: - PADO-TB2 priority list (priority formulations to be investigated/developed in the short term and essential formulations to be developed in the longer term) - PADO-TB2 watch list (promising candidates for investigation/development for children within 5–10 years) - Priority research questions.
Who Operational Handbook On Tuberculosis Module 5
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2022-03-21
Who Operational Handbook On Tuberculosis Module 5 written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-21 with Medical categories.
The aim of this operational handbook is to provide practical guidance on the implementation of the World Health Organization (WHO) policy recommendations on the prevention and management of TB in children and adolescents under programmatic circumstances and at different levels of the health system. The practical guidance aims to inform the development or revision of national policies and related implementation guidance (e.g. handbooks, standard operating procedures) on the management of TB in children and adolescents. This handbook can also help countries adequately plan for the uptake of interventions to better address the specific needs of children and adolescents with or at risk of TB. It can contribute to national efforts to build capacity among national and subnational programme managers and among health workers at all levels of the health care system. The target audience for this handbook includes NTPs and other child health programmes that provide care for children with or at risk of TB, including maternal, newborn, child and adolescent health programmes, HIV services, and PHC programmes. The handbook also targets paediatricians and other health care workers (HCWs) in the public and private sectors, school health services, civil society and community-based organizations, and health care educators.
Roadmap Towards Ending Tb In Children And Adolescents
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2023-11-14
Roadmap Towards Ending Tb In Children And Adolescents written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-14 with Medical categories.
Manuel Op Rationnel De L Oms Sur La Tuberculose Module 5
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Author : World Health Organization
language : fr
Publisher: World Health Organization
Release Date : 2022-10-01
Manuel Op Rationnel De L Oms Sur La Tuberculose Module 5 written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-01 with Medical categories.
Feuille De Route Pour Mettre Fin La Tuberculose De L Enfant Et De L Adolescent
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Author : World Health Organization
language : fr
Publisher: World Health Organization
Release Date : 2024-07-05
Feuille De Route Pour Mettre Fin La Tuberculose De L Enfant Et De L Adolescent written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-05 with Medical categories.
La troisième édition de la feuille de route pour mettre fin à la tuberculose chez les enfants et les adolescents s’appuie sur les versions de 2013 et 2018. La version 2023 reconnaît les progrès réalisés au cours des cinq dernières années et décrit les priorités et les actions clés conçues pour accélérer les progrès vers les objectifs élaborés lors de la réunion de haut niveau de l’Assemblée générale des Nations Unies sur la lutte contre la tuberculose de 2023. La mise en œuvre de ces actions clés aux niveaux mondial, régional, national et infranational devrait permettre de trouver et de traiter davantage d’enfants et d’adolescents atteints de tuberculose ou d’infection tuberculeuse, de prévenir la tuberculose, d’améliorer les résultats du traitement et de prévenir les handicaps associés à la tuberculose. La feuille de route 2023 continue de mettre l’accent sur la tuberculose chez les enfants, tout en soulignant l’importance de lutter contre la tuberculose chez les adolescentes et, pour la première fois, chez les femmes enceintes et post-partum. La troisième édition est alignée sur les directives consolidées et le manuel opérationnel de l’OMS de 2022 sur la prise en charge de la tuberculose chez les enfants et les adolescents.
Infecci N Tuberculosa Latente La Base Del Iceberg
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Author : Fernando Biasutti
language : es
Publisher: Editorial Autores de Argentina
Release Date : 2022-11-15
Infecci N Tuberculosa Latente La Base Del Iceberg written by Fernando Biasutti and has been published by Editorial Autores de Argentina this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-15 with Medical categories.
La "Infección Tuberculosa Latente, la base del iceberg", intenta ser un texto crítico y dinámico con un enfoque actual de un viejo problema. Desde la puesta en discusión de la definición de infección tuberculosa latente, el derribo del enfoque dualista tradicional "infección versus enfermedad", la aparición de conceptos viejos pero renovados como el de las personas "resistentes" y el de la "inmunidad innata entrenada", pasando por la construcción de un modelo de "espectro" de la infección, donde se constituye en una amenaza de difícil diagnóstico a la TB Incipiente y en un desafío y una oportunidad el reconocimiento de la TB Sub-clínica, hasta delinear las estrategias de abordaje en relación a las limitaciones de los test diagnósticos, pero al vertiginoso avance en los tratamientos acortados y finalmente, proponer algoritmos de actuación de utilidad práctica en nuestro medio local. En 11 capítulos se derriban viejos paradigmas, se plantean nuevos interrogantes y se compendian los diferentes escenarios que los médicos afrontamos en el manejo de este problema de salud. En resumen, un texto actualizado, dinámico, de lectura amigable y adaptado a nuestra práctica cotidiana.
Paediatric Drug Optimization Standard Procedure
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Author :
language : en
Publisher: World Health Organization
Release Date : 2021-11-19
Paediatric Drug Optimization Standard Procedure written by and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-19 with Medical categories.
The aim of this document is to provide guidance on how to undertake a paediatric drug optimization (PADO) exercise and identify key priority products for research and development. This guidance is for all technical units undertaking a PADO exercise, all stakeholders involved in PADO processes as well as interested organizations and experts involved in the research and development of therapeutics in the public and private sectors.
Paediatric Drug Optimization For Antibiotics
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2023-03-22
Paediatric Drug Optimization For Antibiotics written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-22 with Medical categories.
Accelerating Optimal Approval Of Priority Formulations For Antibiotic Use In Children
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2024-11-20
Accelerating Optimal Approval Of Priority Formulations For Antibiotic Use In Children written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-20 with Medical categories.
On 24 March 2023, WHO launched the first-ever list of priority paediatric formulations for antibiotics, addressing critical gaps in age-appropriate treatments for infants and children. This list, developed through WHO’s Paediatric Drug Optimization (PADO) process, identifies antibiotics urgently needing development to treat infections from high-priority pathogens. WHO, leveraging GAP-f and partners like GARDP and PENTA, led a technical consultation that concluded in March 2024 to review regulatory frameworks and streamline clinical research, aiming to accelerate regulatory approvals and ensure equitable access to effective treatments. The outcomes of this meeting are captured in this report, underscoring the collaborative efforts needed to advance essential paediatric formulations, minimize delays, and support globally aligned, evidence-based care for serious infections in children.