Rigor And Reproducibility In Genetics And Genomics

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Rigor And Reproducibility In Genetics And Genomics
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Author :
language : en
Publisher: Academic Press
Release Date : 2023-11-08
Rigor And Reproducibility In Genetics And Genomics written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-08 with Medical categories.
Rigor and Reproducibility in Genetics and Genomics: Peer-reviewed, Published, Cited provides a full methodological and statistical overview for researchers, clinicians, students, and post-doctoral fellows conducting genetic and genomic research. Here, active geneticists, clinicians, and bioinformaticists offer practical solutions for a variety of challenges associated with several modern approaches in genetics and genomics, including genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing. Emphasis is placed on rigor and reproducibility throughout, with each section containing laboratory case-studies and classroom activities covering step-by-step protocols, best practices, and common pitfalls. Specific genetic and genomic technologies discussed include microarray analysis, DNA-seq, RNA-seq, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis. Training exercises, supporting data, and in-depth discussions of rigor, reproducibility, and ethics in research together deliver a solid foundation in research standards for the next generation of genetic and genomic scientists. - Provides practical approaches and step-by-step protocols to strengthen genetic and genomic research conducted in the laboratory or classroom - Presents illustrative case studies and training exercises, discussing common pitfalls and solutions for genotyping, gene expression analysis, epigenetic analysis, GWAS, genomic sequencing, and gene editing, among other genetic and genomic approaches - Examines best practices for microarray analysis, DNA-seq, RNA-seq, gene expression validation, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis - Written to provide trainees and educators with highly applicable tools and strategies to learn or refine a method toward identifying meaningful results with high confidence in their reproducibility
Statistical Methods And Applications In Systems Assurance And Quality
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Author : Sotiris Bersimis
language : en
Publisher: CRC Press
Release Date : 2025-10-03
Statistical Methods And Applications In Systems Assurance And Quality written by Sotiris Bersimis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-10-03 with Mathematics categories.
In the era of big data and real-time monitoring, vast amounts of information are generated every second through sensors and advanced tracking systems. The information contained in the data needs to be carefully analyzed and accurate results must be delivered to the users as soon as possible. This book explores the critical role of statistics in modern technologies and applied sciences such as health, informatics, and production systems. Statistical Methods and Applications in Systems Assurance and Quality provides a comprehensive overview of statistical methods for ensuring system quality and reliability. It discusses best practices for improving the quality of manufacturing products by using proper statistical methods. The book covers the current state of statistical methods used for system quality and conveys the importance of healthcare systems and employing statistics in the detection of epidemic outbreaks. Designed for researchers, industry professionals, and academics, this reference is ideal for those working in manufacturing, healthcare, computer engineering, statistical process control, and machine learning applications. It serves as a valuable resource for anyone seeking to enhance system performance through data-driven insights.
Ethical Dimensions Of Ai Development
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Author : Bhattacharya, Pronaya
language : en
Publisher: IGI Global
Release Date : 2024-10-17
Ethical Dimensions Of Ai Development written by Bhattacharya, Pronaya and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-17 with Computers categories.
The digital age has witnessed the meteoric rise of artificial intelligence (AI), a paradigm-shifting technology that has redefined the boundaries of computation and decision-making. Initially, AI's journey began with basic rule-based systems, evolving into the current digital age is dominated by complex machine learning and deep learning models. The digital AI presence and progression has brought with it a myriad of ethical challenges, necessitating a rigorous examination of AI's role in complex and interconnected systems. Ethical Dimensions of AI Development notes that the core of these challenges are issues of privacy, transparency, and validity. AI's ability to process vast datasets can intrude on individual privacy, while opaque algorithmic decision-making processes can obscure transparency. Addressing these ethical concerns is crucial to fostering trust and ensuring the responsible use of AI technologies in society. Covering topics such as accountability, discrimination, and privacy and security, this book is an essential resource for AI researchers and developers, data scientists, ethicists, policy makers, legal professionals, technology industry leaders, and more.
Machine Learning For Neurodegenerative Disorders
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Author : Biswajit Jena
language : en
Publisher: CRC Press
Release Date : 2025-03-31
Machine Learning For Neurodegenerative Disorders written by Biswajit Jena and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-31 with Science categories.
This book explores the application of machine learning to the understanding, early diagnosis, and management of neurodegenerative disorders. With a specific focus on its role in ongoing clinical trials, the book covers essential topics such as data collection, pre-processing, feature extraction, model development, and validation techniques. It delves into the applications of neuroimaging techniques like magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) in the diagnosis and understanding of neurodegenerative disorders. Additionally, the book examines various machine-learning algorithms employed for biomarker discovery in neurodegenerative disorders. It highlights the role of neuroinformatics and big data analysis in advancing the understanding and management of neurodegenerative disorders. Furthermore, the book reviews future prospects and presents the ethical considerations and regulatory challenges associated with implementing machine learning approaches in the diagnosis, treatment, and prevention of neurodegenerative disorders. This comprehensive resource is intended for neuroscientists, students, researchers, and neurologists to understand the emerging scope of machine learning in neurodegenerative disorders.
Advanced Research In Technologies Information Innovation And Sustainability
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Author : Teresa Guarda
language : en
Publisher: Springer Nature
Release Date : 2025-03-04
Advanced Research In Technologies Information Innovation And Sustainability written by Teresa Guarda and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-04 with Computers categories.
This two-volume set, CCIS 2348 and CCIS 2349 ,constitutes the revised selected papers from the International Conference on Advanced Research in Technologies, Information, Innovation and Sustainability 2024, ARTIIS 2024 Workshops, held in Santiago de Chile, Chile, in October 2024. The 55 full papers and 10 short papers presented in these two volumes were carefully reviewed and selected from 170 submissions. These proceedings include papers from the following workshops: Part I: Applications of Computational Mathematics to Simulation and Data Analysis (ACMaSDA 2024); Business, Technology and Digital Transformation (BTDT 2024); Intelligent Systems for Health and Medical Care (ISHMC 2024); Workshop on Gamification Application and Technologies (GAT 2024); Smart Tourism and Information Systems (SMARTTIS 2024). Part II: International Symposium on Technological Innovations for Industry and Society (ISTIIS 2024); International Workshop on Electronic and Telecommunications (IWET 2024); Boosting Tourism using New Technologies (#RTNT2024); Cybersecurity in Information and Communication Technologies (CICT 2024); Bridging Knowledge in a Fragmented World (glossaLAB 2024); Workshop on IoT Networks and Wireless for sustainability (WINWIN-4S 2024); Innovation in Educational Technology (JIUTE 2024).
Genetic Analysis Of Animal Models To Understand The Genomic Architecture Of Substance Use Disorders
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Author : Gary T. Hardiman
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-03
Genetic Analysis Of Animal Models To Understand The Genomic Architecture Of Substance Use Disorders written by Gary T. Hardiman and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-03 with Medical categories.
Rodent Quality Control Genes And Bugs
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Author : Fernando Benavides
language : en
Publisher: Springer Nature
Release Date : 2024-08-12
Rodent Quality Control Genes And Bugs written by Fernando Benavides and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-12 with Medical categories.
This book shows how and why quality assurance programmes should be implemented in laboratory rodent facilities to monitor animal health and genetic status. It covers common practice to assure the desired level of microbiological and genetic surveillance of both genetically standardized and genetically altered laboratory mice and rats. In particular, the book introduces readers to the standardized genetic nomenclature and provides step-by-step protocols for genetic monitoring of the animals. International standards of health monitoring programs are discussed and statistical aspects thereof are explored. Furthermore, the book reviews common infectious diseases in laboratory rodents and guides the reader in monitoring the animals’ health status through application of current diagnostic methods. This book adresses researchers, technicians and zookeepers working in laboratory rodent facilities.
Sa Lik B L M 2024 T Bbi Biyoloji Ve Genetik I
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Author : Hani Hosni Sobhi ALSAADONI
language : tr
Publisher: Efe Akademi Yayınları
Release Date : 2024-10-01
Sa Lik B L M 2024 T Bbi Biyoloji Ve Genetik I written by Hani Hosni Sobhi ALSAADONI and has been published by Efe Akademi Yayınları this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-01 with Medical categories.
İÇİNDEKİLER/BÖLÜMLER GENLERİN ÖTESİNDE: EPİGENETİK Abdussamed Yasin DEMİR EPİGENETİK VE EPİGENOMİK Halime YILDIRIM, Ender M. ÇOŞKUNPINAR POPÜLASYON GENETİĞİ Tuba KÖSE ALMALI, Ender M. COŞKUNPINAR GENETİK HASTALIKLARA KONVANSİYONEL YAKLAŞIMLAR Aslı KARACAN, Seda SÜSGÜN GENETİK HASTALIKLARA YÜKSEK ÇIKTILI MODERN YAKLAŞIMLAR Seda SÜSGÜN MİRNA’LAR VE NÖRODEJENERATİF HASTALIKLAR Hava YILDIRIM, Nur KALUÇ NÖRODEJENERATİF HASTALIKLARDA OKSİDATİF STRESİN ROLÜ Sare Burcu KAYA, Merve BEKER NÖRAL SİSTEMİN KANSER METASTAZINDAKİ ROLÜ Neşe AYŞİT TÜMÖR MİKROÇEVRESİ İLE İLİŞKİLİ KANSERDE İLAÇ DİRENCİ MEKANİZMALARI Sare Burcu KAYA, Ülkan KILIÇ HÜCRE ÖLÜM SÜREÇLERİ: MOLEKÜLER MEKANİZMALAR VE KLİNİK ÖNEMİ Nilüfer ERÇİN ORAK HÜCRELİ ANEMİDE KİŞİSELLEŞTİRİLMİŞ TIP VE KODLANMAYAN RNA'LAR Ümit KARAKAŞ, İrem BEKALP YILMAZ KATLANMAMIŞ PROTEİN YANITI İLE İLİŞKİLİ HASTALIKLAR Bahar SARIKAMIŞ JOHNSON LİZİNÜRİK PROTEİN İNTOLERANSI VE BESLENME YÖNETİMİ Burcu GEZGİÇ, Uğur GÜNŞEN NADİR BİR HASTALIK: X-‘E BAĞLI ADRENOLÖKODİSTROFİ Duygu BEKAR, Uğur GÜNŞEN CRISPR TEKNOLOJİSİ VE TEDAVİLERDE KULLANIMI İrem BEKALP YILMAZ, Ümit KARAKAŞ REKOMBİNANT DNA TEKNOLOJİSİNE KLİNİK YAKLAŞIM Duygu SARI AK
Genetics Genomics And Breeding Of Sugarcane
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Author : Robert J. Henry
language : en
Publisher: CRC Press
Release Date : 2010-08-15
Genetics Genomics And Breeding Of Sugarcane written by Robert J. Henry and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-15 with Science categories.
The fast-growing sugarcane plant is a major source of sugar (sucrose) in tropical and sub-tropical regions. The high productivity of the plant also makes it a key target for use as an energy crop. The fiber of the plant is used to generate electricity and produce ethanol as a fuel.Sugarcane is a hybrid of two species, each of which is genetically c
Neuroimaging In Schizophrenia
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Author : Marek Kubicki
language : en
Publisher: Springer Nature
Release Date : 2020-02-18
Neuroimaging In Schizophrenia written by Marek Kubicki and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-18 with Medical categories.
This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.