Rna Modification In Human Cancers Roles And Therapeutic Implications
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Rna Modification In Human Cancers Roles And Therapeutic Implications
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Author : You Zhou
language : en
Publisher: Frontiers Media SA
Release Date : 2022-04-26
Rna Modification In Human Cancers Roles And Therapeutic Implications written by You Zhou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-26 with Science categories.
Cancer Drug Resistance
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Author : Beverly A. Teicher
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-09
Cancer Drug Resistance written by Beverly A. Teicher and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-09 with Medical categories.
Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.
Rna Based Regulation In Human Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-08-19
Rna Based Regulation In Human Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Medical categories.
RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic Features contributions from leading experts in the field
Rna And Rna Modification In The Pathogenesis Diagnosis And Treatment Of Cancers
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Author : Dong-Hua Yang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-23
Rna And Rna Modification In The Pathogenesis Diagnosis And Treatment Of Cancers written by Dong-Hua Yang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-23 with Medical categories.
Advances In Genetic And Epigenetic Mechanisms Of Therapeutic Resistance In Cancer
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Author : Yilin Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-03
Advances In Genetic And Epigenetic Mechanisms Of Therapeutic Resistance In Cancer written by Yilin Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-03 with Science categories.
Genetics And Epigenetics Of Rna Methylation System In Human Cancers
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Author : Shicheng Guo
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-17
Genetics And Epigenetics Of Rna Methylation System In Human Cancers written by Shicheng Guo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-17 with Science categories.
Advances In Transcriptomics Research And Their Applications In Human Diseases
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Author : Hua Zhong
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-05
Advances In Transcriptomics Research And Their Applications In Human Diseases written by Hua Zhong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-05 with Science categories.
Rna Mediated Epigenetic And Transcriptional Regulation
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Author : Yicheng Long
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-29
Rna Mediated Epigenetic And Transcriptional Regulation written by Yicheng Long and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-29 with Science categories.
Rna Therapeutics
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Author : Mouldy Sioud
language : en
Publisher: Humana Press
Release Date : 2011-03-04
Rna Therapeutics written by Mouldy Sioud and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-04 with Science categories.
Central to the synthesis of proteins, the performance of catalysis, and many other physiological processes, the aberrant expression of which can be linked to human diseases including cancers, RNA has proven to be key target for therapeutics as well as a tool for therapy. In RNA Therapeutics: Function, Design, and Delivery, expert contributors from a broad spectrum of scientific backgrounds highlight the roles that messenger RNAs and small RNAs can play in biology and medicine. While covering the five major RNA-based drugs, namely the use of ribozymes to cleave and/or correct mRNA transcript, the use of siRNA for targeted silencing of gene transcripts, the use of aptamers, like short RNA molecules, for neutralizing the protein functions, the use mRNA-transfected DCs to activate immune system against tumor cells, as well as the use of RNA to reprogram T and/or DC cell function, this extensive volume brings together the fields of coding (mRNA) and non-coding RNA such as ribozymes, RNAse P, siRNAs, and miRNAs into one convenient source. Written in the highly successful Methods in Molecular BiologyTM series format, the cutting-edge protocol chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and practical tips on troubleshooting and avoiding known pitfalls. Also, the book contains several excellent reviews for teaching purposes. Authoritative and comprehensive, RNA Therapeutics: Function, Design, and Delivery provides key models and tools which will assist researchers in increasing our understanding of RNA functions, modifications, and their involvement in diseases in order to lead to the design of vital new RNA-based therapeutics.
Genetic And Proteomic Biomarkers In Solid Tumor Detection And Treatment
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Author : Jitian Li
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-07
Genetic And Proteomic Biomarkers In Solid Tumor Detection And Treatment written by Jitian Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-07 with Science categories.