Road To Regulation Of Endocrine Disruptors And Combination Effects
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Road To Regulation Of Endocrine Disruptors And Combination Effects
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Author : Karina Petersen
language : en
Publisher: Nordic Council of Ministers
Release Date : 2014-05-06
Road To Regulation Of Endocrine Disruptors And Combination Effects written by Karina Petersen and has been published by Nordic Council of Ministers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-06 with categories.
Discussions regarding regulation of endocrine disruptors (EDs) and combination effects are ongoing in Europe. Among the central topics of discussion are establishment of criteria for identification of EDs, whether there is a threshold for endocrine disrupting effects and how EDs should be handled within relevant EU regulations. In addition, a roadmap for further EU work regarding combination effects has been presented, but more detailed discussions are needed regarding scientific issues and regulatory intervention. Possible Member State initiatives to provide input to these EU processes were discussed in a Nordic workshop held in Oslo in November 2013. This report describes the workshop presentations, initiatives and thoughts from each of the Nordic countries, the plenary discussions, and the main workshop outcomes.
Road To Regulation Of Endocrine Disruptors And Combination Effects
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Author : Birgitte Lindeman
language : en
Publisher:
Release Date : 2014
Road To Regulation Of Endocrine Disruptors And Combination Effects written by Birgitte Lindeman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Discussions regarding regulation of endocrine disruptors (EDs) and combination effects are ongoing in Europe. Among the central topics of discussion are establishment of criteria for identification of EDs, whether there is a threshold for endocrine disrupting effects and how EDs should be handled within relevant EU regulations. In addition, a roadmap for further EU work regarding combination effects has been presented, but more detailed discussions are needed regarding scientific issues and regulatory intervention. Possible Member State initiatives to provide input to these EU processes were discussed in a Nordic workshop held in Oslo in November 2013. This report describes the workshop presentations, initiatives and thoughts from each of the Nordic countries, the plenary discussions, and the main workshop outcomes
Endocrine Disruptors In The Environment
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Author : Sushil K. Khetan
language : en
Publisher: John Wiley & Sons
Release Date : 2014-05-23
Endocrine Disruptors In The Environment written by Sushil K. Khetan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-23 with Technology & Engineering categories.
Endocrine Disruptors in the Environment A concise and engaging overview of endocrine disruption phenomena that brings complex concepts within the reach of non-specialists For most of the last decade, the science of endocrine disruption has evolved with more definitive evidence of its damaging potential to health and environment. This book lists the major environmental chemicals of concern and their mechanism of endocrine disruption including remedial measures for them. Divided into three parts, Endocrine Disruptors in the Environment begins with an overview of the endocrine system and endocrine disruptors, discussing their salient features and presenting a historical perspective of endocrine disruption phenomena. It then goes on to cover hormone- signaling mechanisms, followed by various broad classes of putative endocrine disruptors, before introducing readers to environmental epigenetic modifications. Part two of the book focuses on removal processes of various EDCs by biotic and abiotic transformation/degradation. The last section consists of four chapters embracing themes on finding solutions to environmental EDCs—including their detection, regulation, replacement, and remediation. Endocrine Disruptors in the Environment is the first book to detail the endocrine effects of several known environmental contaminants and their mechanism of endocrine disruption. Additionally, it: Covers both the chemistry and biology of endocrine disruption and compiles almost all the known endocrine disrupting environmental chemicals and their mechanisms of toxicity Addresses policy and regulatory issues relevant to EDCs including scientific uncertainty and precautionary policy Brings forth the use of Green Chemistry principles in avoiding endocrine disruption in the designing and screening for safer chemicals and remediation of the EDCs in aquatic environment Includes a useful glossary of technical terms, a list of acronyms, topical references, and a subject index Endocrine Disruptors in the Environment is an ideal book for environmental chemists and endocrine toxicologists, developmental biologists, endocrinologists, epidemiologists, environmental health scientists and advocates, and regulatory officials tasked with risk assessment in environment and health areas.
Endocrine Disrupters Combination Effects
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Author :
language : en
Publisher: Nordic Council of Ministers
Release Date : 2011
Endocrine Disrupters Combination Effects written by and has been published by Nordic Council of Ministers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
Chemical Cocktails A Serious Matter Of Concern
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Author : Nordiska Ministerrådet
language : en
Publisher: Nordic Council of Ministers
Release Date : 2012
Chemical Cocktails A Serious Matter Of Concern written by Nordiska Ministerrådet and has been published by Nordic Council of Ministers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
Challenges In Endocrine Disruptor Toxicology And Risk Assessment
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Author : Alexandra Fucic
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-12-08
Challenges In Endocrine Disruptor Toxicology And Risk Assessment written by Alexandra Fucic and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-08 with Science categories.
Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology - including interactions with other hormone pathways - has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer's disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.
Endocrine Disruption And Human Health
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Author : Philippa D. Darbre
language : en
Publisher: Academic Press
Release Date : 2021-09-19
Endocrine Disruption And Human Health written by Philippa D. Darbre and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-19 with Medical categories.
Updated with new and expanded chapters, Endocrine Disruption and Human Health, Second Edition provides an introduction to what endocrine disruptors are, the issues surrounding them, the source of these chemicals in the ecosystem and the mechanisms of action and assay systems. Contributions by specialists are included to discuss the varying effects of endocrine disruption on human health, and procedures for risk assessment of endocrine disruptors, and current approaches to their regulation are also covered. With new material on topics such as low-term, low dose mixtures, windows of susceptibility, epigenetics, EDCs effect on the gut microbiome, EDCs in from polluted air and oral exposures, green chemistry, and nanotechnology, the new edition of Endocrine Disruption and Human Health is a valuable and informative text for academic and clinical researchers and other health professionals approaching endocrine disruption and its effects on human health for the first time, graduate students, and advanced undergraduate students. Provides readers with access to a range of information from the basic mechanisms and assays through to cutting-edge research investigating concerns for human health Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations Newly added content on topics like low-term, low dose mixtures, windows of susceptibility to EDCs, EDCs effect on the gut microbiome, green chemistry, and nanotechnology
Hormonally Active Agents In The Environment
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2000-02-03
Hormonally Active Agents In The Environment written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-03 with Science categories.
Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.
Pesticide Policy And Politics In The European Union
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Author : Emanuela Bozzini
language : en
Publisher: Springer
Release Date : 2017-03-23
Pesticide Policy And Politics In The European Union written by Emanuela Bozzini and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-23 with Political Science categories.
This book explores the regulation of pesticides in the European Union in order to reveal the complex, controversial, and contested nature of an assessment system proudly declared by the EU to be ‘the strictest in the world’. The current regulatory framework is based on Regulation 1107/2009, which substantially reformed the previous system. The analysis describes the new criteria and procedures for the authorization of active substances to be used in the production of pesticides, traces the lengthy policy formulation process, and identifies factors that made policy change possible. Further, the book illustrates the current controversies that characterise the implementation of Regulation 1107/2009: the ban of pesticides harmful to pollinators, the renewal of the authorization of glyphosate, and the definition of criteria for the assessment of endocrine disruption. The author provides information on policy outcomes and highlights persisting shortcomings in the enforcement of EU regulation. This book will appeal to students and scholars from a variety of disciplines, including political science, political sociology, and public policy.
New Eu Criteria For Endocrine Disrupters
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Author : Nordic Council of Ministers
language : en
Publisher: Nordic Council of Ministers
Release Date : 2018-08-30
New Eu Criteria For Endocrine Disrupters written by Nordic Council of Ministers and has been published by Nordic Council of Ministers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-30 with Technology & Engineering categories.
Endocrine disruptors (EDs) are substances that adversely affect hormone function. The effects by EDs are thought to depend on both dose and timing of exposure, especially during foetal development. The upcoming EU regulation on identification of EDs, application biocides and pesticides, will have an impact on all actors of the food chain. The consequences of a ban of EDs in foods were discussed in a Nordic workshop (Uppsala, 29-30 Nov 2016) where risk assessors and managers from Nordic food authorities, industry, trade associations, consumer organizations and researchers were represented. It was recognized by all participants that a ban was particularly challenging for the production chain since there are few viable alternatives. A harmonized EU legislation based on scientific risk assessment was preferred compared to national specific legislation as it treats all the actors equally.