New Eu Criteria For Endocrine Disrupters
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New Eu Criteria For Endocrine Disrupters
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Author : Nordic Council of Ministers
language : en
Publisher: Nordic Council of Ministers
Release Date : 2018-08-30
New Eu Criteria For Endocrine Disrupters written by Nordic Council of Ministers and has been published by Nordic Council of Ministers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-30 with Technology & Engineering categories.
Endocrine disruptors (EDs) are substances that adversely affect hormone function. The effects by EDs are thought to depend on both dose and timing of exposure, especially during foetal development. The upcoming EU regulation on identification of EDs, application biocides and pesticides, will have an impact on all actors of the food chain. The consequences of a ban of EDs in foods were discussed in a Nordic workshop (Uppsala, 29-30 Nov 2016) where risk assessors and managers from Nordic food authorities, industry, trade associations, consumer organizations and researchers were represented. It was recognized by all participants that a ban was particularly challenging for the production chain since there are few viable alternatives. A harmonized EU legislation based on scientific risk assessment was preferred compared to national specific legislation as it treats all the actors equally.
New Eu Criteria For Endocrine Disrupters
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Author :
language : en
Publisher:
Release Date : 2018
New Eu Criteria For Endocrine Disrupters written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Road To Regulation Of Endocrine Disruptors And Combination Effects
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Author : Karina Petersen
language : en
Publisher: Nordic Council of Ministers
Release Date : 2014-05-06
Road To Regulation Of Endocrine Disruptors And Combination Effects written by Karina Petersen and has been published by Nordic Council of Ministers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-06 with categories.
Discussions regarding regulation of endocrine disruptors (EDs) and combination effects are ongoing in Europe. Among the central topics of discussion are establishment of criteria for identification of EDs, whether there is a threshold for endocrine disrupting effects and how EDs should be handled within relevant EU regulations. In addition, a roadmap for further EU work regarding combination effects has been presented, but more detailed discussions are needed regarding scientific issues and regulatory intervention. Possible Member State initiatives to provide input to these EU processes were discussed in a Nordic workshop held in Oslo in November 2013. This report describes the workshop presentations, initiatives and thoughts from each of the Nordic countries, the plenary discussions, and the main workshop outcomes.
Oecd Conceptual Framework For Testing And Assessment Of Endocrine Disrupters As A Basis For Regulation Of Substances With Endocrine Disrupting Properties
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Author : Nordic Council of Ministers
language : en
Publisher:
Release Date : 2004
Oecd Conceptual Framework For Testing And Assessment Of Endocrine Disrupters As A Basis For Regulation Of Substances With Endocrine Disrupting Properties written by Nordic Council of Ministers and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
The existing EU chemical legislation only covers some of the effects caused by endocrine disruption. In the proposal for the new REACH system, endocrine disrupters are covered by the authorisation procedure based on a case-by-case assessment, but no indication of criteria for the assessment is given. Several toxicological and ecotoxicological screening tests for predicting endocrine disrupting properties of a chemical are now under development and international validation within the OECD, but it will probably take several years before the full range of validated testing methods and criteria are developed. In the meantime there is a need for guidance on how to interpret test results from existing test methods and how to identify a substance as an endocrine disrupter. Regulatory instruments that can be used towards endocrine disrupters should also be considered in this interim period. The aim of this project has been to investigate if and how the OECD Conceptual Framework for Testing and Assessment of Endocrine Disrupters can be used as a basis for regulatory initiatives towards endocrine disrupters. The report includes an assessment of the tests in the OECD Conceptual Framework, including specification of the endpoint for the test and reliability and relevance for effects in humans. This report is expected to serve as a basis for the Nordic contribution to the discussions in EU on interpretation and use of test results indicating endocrine disruption for regulatory purposes and furthermore, how to integrate endocrine disrupters in the new EU chemicals regulation
Road To Regulation Of Endocrine Disruptors And Combination Effects
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Author : Birgitte Lindeman
language : en
Publisher:
Release Date : 2014
Road To Regulation Of Endocrine Disruptors And Combination Effects written by Birgitte Lindeman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Discussions regarding regulation of endocrine disruptors (EDs) and combination effects are ongoing in Europe. Among the central topics of discussion are establishment of criteria for identification of EDs, whether there is a threshold for endocrine disrupting effects and how EDs should be handled within relevant EU regulations. In addition, a roadmap for further EU work regarding combination effects has been presented, but more detailed discussions are needed regarding scientific issues and regulatory intervention. Possible Member State initiatives to provide input to these EU processes were discussed in a Nordic workshop held in Oslo in November 2013. This report describes the workshop presentations, initiatives and thoughts from each of the Nordic countries, the plenary discussions, and the main workshop outcomes
Endocrine Disruption And Human Health
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Author : Philippa D. Darbre
language : en
Publisher: Academic Press
Release Date : 2015-03-21
Endocrine Disruption And Human Health written by Philippa D. Darbre and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-21 with Medical categories.
Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations
Pesticide Policy And Politics In The European Union
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Author : Emanuela Bozzini
language : en
Publisher: Springer
Release Date : 2017-03-23
Pesticide Policy And Politics In The European Union written by Emanuela Bozzini and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-23 with Political Science categories.
This book explores the regulation of pesticides in the European Union in order to reveal the complex, controversial, and contested nature of an assessment system proudly declared by the EU to be ‘the strictest in the world’. The current regulatory framework is based on Regulation 1107/2009, which substantially reformed the previous system. The analysis describes the new criteria and procedures for the authorization of active substances to be used in the production of pesticides, traces the lengthy policy formulation process, and identifies factors that made policy change possible. Further, the book illustrates the current controversies that characterise the implementation of Regulation 1107/2009: the ban of pesticides harmful to pollinators, the renewal of the authorization of glyphosate, and the definition of criteria for the assessment of endocrine disruption. The author provides information on policy outcomes and highlights persisting shortcomings in the enforcement of EU regulation. This book will appeal to students and scholars from a variety of disciplines, including political science, political sociology, and public policy.
Neuroendocrine Regulation Of Animal Vocalization
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Author : Cheryl S. Rosenfeld
language : en
Publisher: Academic Press
Release Date : 2020-12-04
Neuroendocrine Regulation Of Animal Vocalization written by Cheryl S. Rosenfeld and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-04 with Nature categories.
Neuroendocrine Regulation of Animal Vocalization: Mechanisms and Anthropogenic Factors in Animal Communication examines the underpinning neuroendocrine (NE) mechanisms that drive animal communication across taxa. Written by international subject experts, the book focuses on the importance of animal communication in survival and reproduction at an individual and species level, and the impact that increased production and accumulation of endocrine-disrupting chemicals (EDCs) can have on these regulatory processes. This book discusses sound production, perception, processing, and response across a range of animals. This includes insects, fish, bats, birds, nonhuman primates, infant humans, and many others. Some chapters analyze how neuroactive substances, endocrine control, and chemical pollution affect the physiology of the animal’s perceptive and sound-producing organs, as well as their auditory and vocal receptors and pathways. Other chapters address the recent approaches governments have taken to protect against the endocrine disruption of animal (vocal) behaviors. The book is a valuable resource for researchers and advanced students seeking first-rate material on neuroendocrinological effects on animal behavior and communication. Serves as the most comprehensive cross-taxa study of its kind, revolutionary in its focus on the impacts of EDCs on the processes guiding animal communication Emphasizes the importance of production, perception and processing of acoustic vocalization for survival Analyzes recent governmental policies and protections against the effects of EDCs on humans and wildlife
Environmental Endocrinology And Endocrine Disruptors
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Author : Rosario Pivonello
language : en
Publisher: Springer Nature
Release Date : 2023-04-20
Environmental Endocrinology And Endocrine Disruptors written by Rosario Pivonello and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-20 with Medical categories.
This book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and offers an extensive overview of downstream endocrinological and endocrinological-related disorders. In addition, several chapters focus on transgenerational actions, which are a topic of particular interest. Lastly, evidence from preclinical and clinical studies provides the basis for an in-depth, critical discussion of each topic. The book is part of the SpringerReference program, which provides access to ‘living editions’ that are constantly updated using a dynamic peer-review publishing process.
Challenges In Endocrine Disruptor Toxicology And Risk Assessment
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Author : Alexandra Fucic
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-12-08
Challenges In Endocrine Disruptor Toxicology And Risk Assessment written by Alexandra Fucic and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-08 with Science categories.
Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology - including interactions with other hormone pathways - has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer's disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.