Role Of Gut Microbiota In Type 2 Diabetes Mellitus Pathogenesis
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Role Of Gut Microbiota In Type 2 Diabetes Mellitus Pathogenesis
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Author : Nicola Mariano Cinquepalmi
language : en
Publisher:
Release Date : 2016
Role Of Gut Microbiota In Type 2 Diabetes Mellitus Pathogenesis written by Nicola Mariano Cinquepalmi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Emerging Roles Of The Gut Microbiota In The Pathogenesis Of Metabolic Disorders
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Author : Isabel Moreno-Indias
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-01
Emerging Roles Of The Gut Microbiota In The Pathogenesis Of Metabolic Disorders written by Isabel Moreno-Indias and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-01 with Medical categories.
Role Of Gut Microbiota In Diabetes Mellitus And Tumor Immunity
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Author : Zhe-Sheng Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-02
Role Of Gut Microbiota In Diabetes Mellitus And Tumor Immunity written by Zhe-Sheng Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-02 with Medical categories.
Gut Microbiota Potential In Type 2 Diabetes
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Author : Shahzad Irfan
language : en
Publisher:
Release Date : 2019
Gut Microbiota Potential In Type 2 Diabetes written by Shahzad Irfan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Medical categories.
Appropriate metabolic regulation is vital for health. Multiple factors play important roles in maintaining the metabolic system in different physiological conditions. These factors range from intestinal metabolism of food and absorption of nutrients, pancreatic hormones and their interplay under feeding and fasting, hepatic regulation of macronutrient formation and metabolism storage of macronutrients in skeletal muscles. Intestinal metabolism of ingested food and subsequent nutrient absorption depends on the symbiotic microbial community residing in the gut. The specific ratio of different microbial phyla in the gut has proved to be extremely important for the beneficial role of the gut microbiome. The importance of gut microbiome in the regulation of metabolism has been highlighted with reports of the abnormal ratio of gut microbial community resulting in different metabolic disturbances ranging from obesity to the development of diabetes mellitus. The physiological impact of insulin on the metabolic regulation of macronutrients has recently been shown to be augmented by the secondary metabolites produced by anaerobic fermentation. The current chapter aims to highlight recent findings in the regulation of extraintestinal metabolism by gut microbiome with a specific emphasis on the physiology and pathophysiology of the pancreas in health and disease.
Nutrition And Diabetes
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Author : Emmanuel C. Opara
language : en
Publisher: CRC Press
Release Date : 2019-01-03
Nutrition And Diabetes written by Emmanuel C. Opara and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-03 with Medical categories.
Diabetes occurs at such an alarming rate that it can be described as a global epidemic. Following its predecessor, Nutrition and Diabetes: Pathophysiology and Management, Second Edition, is a comprehensive resource that describes various factors that drive the accumulation of excess body weight and fat resulting in obesity. The book discusses the metabolic aberrations found in obesity and how they lead to the association of obesity with diabetes. This new edition highlights the role played by diet and the interrelationships in the metabolism of key nutrients in the pathogenesis of obesity and diabetes which provides the scientific basis for treatment and management approaches. Features Highlights the role of nutrition in the pathogenesis of obesity and diabetes Organized logically into two easy-to-use sections - Pathophysiology and Management of Obesity and Pathophysiology and Treatment of Diabetes Features emerging therapeutic approaches for management of obesity and diabetes Discusses experience in the management of obesity and diabetes in developing countries Presents challenges in insulin therapy and provides guidelines to overcome them The first section of the book retains key topics from the previous edition and contains new chapters including genetic determinants of nutrient processing; fat distribution and diabetes mellitus; combined effect of diet and physical activity in the management of obesity; pharmacologic treatment of obesity; and the role of gut microbiota in the pathogenesis and treatment of obesity. The second section features updated versions of most of the other chapters in the first edition comprising a modified chapter on oxidative stress and the effects of dietary supplements on glycemic control in Type 2 diabetes. In addition, new chapters are added in this section and include the contribution of iron and transition metal micronutrients to diabetes; role of microbiota in the pathogenesis and treatment of diabetes; primary prevention of Type 2 diabetes; and the pathophysiology and management of Type 1 diabetes.
The Gut Microbiota A Driver Of Type 2 Diabetes
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Author :
language : en
Publisher:
Release Date : 2023
The Gut Microbiota A Driver Of Type 2 Diabetes written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with categories.
The studies described in this thesis investigated how changes in the gut microbiota relate to alterations in the immune system and the development of beta-cell dysfunction. Moreover, we addressed the interrelation between intestinal immunoglobulins and gut microbiota in individuals with metabolic diseases. Chapter 1 provides a general introduction to the gut microbiota, the pathogenesis of T2D, and the function of IgA. Chapter 2 summarizes the current literature on gut microbiota, obesity, and T2D. A western diet leads to changes in gut microbial composition and intestinal physiology. Altered intestinal microbial composition promotes obesity by increasing energy harvest and gut permeability that may facilitate the translocation of bacteria or bacterial components into the circulation. Thereby, the gut microbiota can impact the function of metabolic organs. Interventions aiming to restore gut microbial homeostasis, such as ingestion of fibers or therapeutic microbes, are novel strategies to reduce metabolic abnormalities. Inflammation in the pancreas can lead to beta-cell dysfunction with the driving inflammatory triggers yet to be identified. The gut microbiota provides a plausible source of pro-inflammatory molecules. Chapter 3 shows that a high-fat diet significantly altered the gut and pancreatic bacterial signature in mice. Importantly, our findings could not be traced back to contamination, a well-known factor disturbing microbial signal identification in low-abundance samples. Our data point out that the pancreas comprises bacterial DNA. This underscores similar speculations and observations in the field implying that gut microbial components translocate and act on distal organs and tissue. Chapter 4 summarizes the current literature on gut microbiota and metabolic inflammation. T2D is characterized by a chronic state of low-grade inflammation, which has been linked to the development of insulin resistance. Intestinal microbiota drive the development of insuli
Gut Microbiota In Relation To Pathogenesis Of Obesity And Type 2 Diabetes
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Author : Shantha Devi Udayappan
language : en
Publisher:
Release Date : 2018
Gut Microbiota In Relation To Pathogenesis Of Obesity And Type 2 Diabetes written by Shantha Devi Udayappan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Next Generation Probiotics From Commensal Bacteria To Novel Drugs And Food Supplements
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Author : Philippe Langella
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-22
Next Generation Probiotics From Commensal Bacteria To Novel Drugs And Food Supplements written by Philippe Langella and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-22 with categories.
Microbial Endocrinology
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Author : Mark Lyte
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-04-06
Microbial Endocrinology written by Mark Lyte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-06 with Medical categories.
Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.
Pathophysiology
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Author : David C. Gaze
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-05-30
Pathophysiology written by David C. Gaze and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-30 with Medical categories.
Pathophysiology is the convergence of pathology (the discipline of observed changes in a diseased state) with physiology (the mechanisms of systems operation). It represents the functional changes that occur because of injury or disease. This volume provides state-of-the-art up-to-date literature reviews on pathophysiological processes in a number of disease states. The book is organised methodically in a head-to-toe systems approach examining aspects of neuropathophysiology, endocrine pathophysiology, structural biology, renal pathophysiology and genitourinary pathophysiology. This short volume on pathophysiology is intended for general medical and biomedical students at both undergraduate and postgraduate levels. In addition, it is a useful short update of recent advances in research and translational biology to those working in academia or healthcare science.