School Of Bio And Chemical Engineering Sequence Analysis

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Optimization In Medicine And Biology

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Author : Gino J. Lim
language : en
Publisher: CRC Press
Release Date : 2008-01-08

Optimization In Medicine And Biology written by Gino J. Lim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-08 with Business & Economics categories.

Thanks to recent advancements, optimization is now recognized as a crucial component in research and decision-making across a number of fields. Through optimization, scientists have made tremendous advances in cancer treatment planning, disease control, and drug development, as well as in sequencing DNA, and identifying protein structures. Op

Systems Biology And Ecology Of Microbial Mat Communities

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Author : Martin G. Klotz
language : en
Publisher: Frontiers Media SA
Release Date : 2016-04-11

Systems Biology And Ecology Of Microbial Mat Communities written by Martin G. Klotz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-11 with Microbiology categories.

Microbial mat communities consist of dense populations of microorganisms embedded in exopolymers and/or biomineralized solid phases, and are often found in mm-cm thick assemblages, which can be stratified due to environmental gradients such as light, oxygen or sulfide. Microbial mat communities are commonly observed under extreme environmental conditions, deriving energy primarily from light and/or reduced chemicals to drive autotrophic fixation of carbon dioxide. Microbial mat ecosystems are regarded as living analogues of primordial systems on Earth, and they often form perennial structures with conspicuous stratifications of microbial populations that can be studied in situ under stable conditions for many years. Consequently, microbial mat communities are ideal natural laboratories and represent excellent model systems for studying microbial community structure and function, microbial dynamics and interactions, and discovery of new microorganisms with novel metabolic pathways potentially useful in future industrial and/or medical applications. Due to their relative simplicity and organization, microbial mat communities are often excellent testing grounds for new technologies in microbiology including micro-sensor analysis, stable isotope methodology and modern genomics. Integrative studies of microbial mat communities that combine modern biogeochemical and molecular biological methods with traditional microbiology, macro-ecological approaches, and community network modeling will provide new and detailed insights regarding the systems biology of microbial mats and the complex interplay among individual populations and their physicochemical environment. These processes ultimately control the biogeochemical cycling of energy and/or nutrients in microbial systems. Similarities in microbial community function across different types of communities from highly disparate environments may provide a deeper basis for understanding microbial community dynamics and the ecological role of specific microbial populations. Approaches and concepts developed in highly-constrained, relatively stable natural communities may also provide insights useful for studying and understanding more complex microbial communities.

Life Out Of Sequence

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Author : Hallam Stevens
language : en
Publisher: University of Chicago Press
Release Date : 2013-11-04

Life Out Of Sequence written by Hallam Stevens and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-04 with Science categories.

Thirty years ago, the most likely place to find a biologist was standing at a laboratory bench, peering down a microscope, surrounded by flasks of chemicals and petri dishes full of bacteria. Today, you are just as likely to find him or her in a room that looks more like an office, poring over lines of code on computer screens. The use of computers in biology has radically transformed who biologists are, what they do, and how they understand life. In Life Out of Sequence, Hallam Stevens looks inside this new landscape of digital scientific work. Stevens chronicles the emergence of bioinformatics—the mode of working across and between biology, computing, mathematics, and statistics—from the 1960s to the present, seeking to understand how knowledge about life is made in and through virtual spaces. He shows how scientific data moves from living organisms into DNA sequencing machines, through software, and into databases, images, and scientific publications. What he reveals is a biology very different from the one of predigital days: a biology that includes not only biologists but also highly interdisciplinary teams of managers and workers; a biology that is more centered on DNA sequencing, but one that understands sequence in terms of dynamic cascades and highly interconnected networks. Life Out of Sequence thus offers the computational biology community welcome context for their own work while also giving the public a frontline perspective of what is going on in this rapidly changing field.

Network Bioscience 2nd Edition

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Author : Marco Pellegrini
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-27

Network Bioscience 2nd Edition written by Marco Pellegrini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-27 with categories.

Network science has accelerated a deep and successful trend in research that influences a range of disciplines like mathematics, graph theory, physics, statistics, data science and computer science (just to name a few) and adapts the relevant techniques and insights to address relevant but disparate social, biological, technological questions. We are now in an era of 'big biological data' supported by cost-effective high-throughput genomic, transcriptomic, proteomic, metabolomic data collection techniques that allow one to take snapshots of the cells' molecular profiles in a systematic fashion. Moreover recently, also phenotypic data, data on diseases, symptoms, patients, etc. are being collected at nation-wide level thus giving us another source of highly related (causal) 'big data'. This wealth of data is usually modeled as networks (aka binary relations, graphs or webs) of interactions, (including protein-protein, metabolic, signaling and transcription-regulatory interactions). The network model is a key view point leading to the uncovering of mesoscale phenomena, thus providing an essential bridge between the observable phenotypes and 'omics' underlying mechanisms. Moreover, network analysis is a powerful 'hypothesis generation' tool guiding the scientific cycle of 'data gathering', 'data interpretation, 'hypothesis generation' and 'hypothesis testing'. A major challenge in contemporary research is the synthesis of deep insights coming from network science with the wealth of data (often noisy, contradictory, incomplete and difficult to replicate) so to answer meaningful biological questions, in a quantifiable way using static and dynamic properties of biological networks.

Interdisciplinary Research And Applications In Bioinformatics Computational Biology And Environmental Sciences

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Author : Liu, Limin Angela
language : en
Publisher: IGI Global
Release Date : 2010-10-31

Interdisciplinary Research And Applications In Bioinformatics Computational Biology And Environmental Sciences written by Liu, Limin Angela and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-31 with Computers categories.

"This book presents cutting-edge research in the field of computational and systems biology, presenting studies ranging from the atomic/molecular level to the genomic level and covering a wide spectrum of important biological problems and applications"--Provided by publisher.

A Proposed Framework For Identifying Potential Biodefense Vulnerabilities Posed By Synthetic Biology

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-12-20

A Proposed Framework For Identifying Potential Biodefense Vulnerabilities Posed By Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-20 with Science categories.

Building on an increasingly sophisticated understanding of naturally occurring biological processes, researchers have developed technologies to predictably modify or create organisms or biological components. This research, known collectively as synthetic biology, is being pursued for a variety of purposes, from reducing the burden of disease to improving agricultural yields to remediating pollution. While synthetic biology is being pursued primarily for beneficial and legitimate purposes, it is possible to imagine malicious uses that could threaten human health or military readiness and performance. Making informed decisions about how to address such concerns requires a comprehensive, realistic assessment. To this end, the U.S. Department of Defense, working with other agencies involved in biodefense, asked the National Academies of Sciences, Engineering, and Medicine to develop a framework to guide an assessment of the security concerns related to advances in synthetic biology, to assess the level of concern warranted for various advances and identify areas of vulnerability, and to prioritize options to address these vulnerabilities. This interim report proposes a framework for identifying and prioritizing potential areas of concern associated with synthetic biologyâ€"a tool to aid the consideration of concerns related to synthetic biology. The framework describes categories of synthetic biology technologies and applicationsâ€"such as genome editing, directed evolution, and automated biological designâ€"and provides a set of initial questions to guide the assessment of concern related to these technologies and applications.

New Developments In Biotechnology U S Investment In Biotechnology Summary

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Author :
language : en
Publisher:
Release Date : 1988

New Developments In Biotechnology U S Investment In Biotechnology Summary written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Biotechnology categories.

Us Black Engineer It

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Author :
language : en
Publisher:
Release Date : 1994

Us Black Engineer It written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.

Iterative Design Of Teaching Learning Sequences

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Author : Dimitris Psillos
language : en
Publisher: Springer
Release Date : 2015-11-24

Iterative Design Of Teaching Learning Sequences written by Dimitris Psillos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-24 with Science categories.

This book addresses a very important aspect of science education and science education research respectively: The research-based development of Teaching Learning Sequences. The authors elaborate on important theoretical issues as well as aspects of the design and iterative evolution of a several Teaching Learning Sequences in a modern scientific and technological field which is socially relevant and educationally significant. The book is divided into two parts. The first part includes a collection of papers discussing the theoretical foundations and characteristics of selected theoretical frameworks related to designing Teaching Learning Sequences, elaborate on common issues and draw on the wider perspective of design research in education. The second part contains a collection of papers presenting case studies concerning the design, implementation, iterative evolution and evaluation of Teaching and Learning Sequences in a variety of educational context. The case studies deal with a more or less new subject matter, a part of modern interdisciplinary science, material science, which enhances the connections between science and technology. From a wider perspective the case studies draw on existing theoretical ideas on inquiry in various contexts and provide powerful suggestions for contextualized innovation in a variety of school systems and existing practices.

Biodefense In The Age Of Synthetic Biology

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2019-01-05

Biodefense In The Age Of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-05 with Technology & Engineering categories.

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.