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Selective Sample Handling And Detection In High Performance Liquid Chromatography

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Selective Sample Handling And Detection In High Performance Liquid Chromatography

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Author :
language : en
Publisher: Elsevier
Release Date : 1987-12-01

Selective Sample Handling And Detection In High Performance Liquid Chromatography written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-12-01 with Science categories.

This book is the first of a two-volume project which attempts to treat the sample handling and detection processes in a liquid chromatographic system in an integrated fashion. The need for more selective and sensitive chromatographic methods to help solve the numerous trace analysis problems in complex samples is undisputed. However, few workers realize the strong interdependence of the various steps - sample handling, separation and detection - which must be considered if one wants to arrive at an optimal solution. By introducing a strong element of selectivity and trace enrichment in the sample preparation step, fewer demands are placed on the quality of the chromatography and often a simple UV detector can be used. By using a selective detection mode, i.e. a reaction detector, the sample handling step can frequently be simplified and more easily automated. The impact of such a ``total system'' approach on handling series of highly complex samples such as environmental specimens or biological fluids can be easily imagined.Each chapter includes sufficient references to the literature to serve as a valuable starting point for more detailed investigation. Special emphasis is placed on the sample handling, and high priority has been given to the treatment of chemical principles applied to the topics presented, rather than to instrumentation. Written by experienced practitioners, this volume will be of interest to investigators in many areas of application, including environmental scientists and those active in the clinical, pharmaceutical and bioanalytical fields.

Selective Sample Handling And Detection In High Performance Liquid Chromatography

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Author : Roland W. Frei
language : en
Publisher:
Release Date : 1988

Selective Sample Handling And Detection In High Performance Liquid Chromatography written by Roland W. Frei and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with categories.

Selective Sample Handling And Detection In High Performance Liquid Chromatography

DOWNLOAD
Author : Roland W. Frei
language : en
Publisher:
Release Date : 1988

Selective Sample Handling And Detection In High Performance Liquid Chromatography

DOWNLOAD
Author : Roland W. Frei
language : en
Publisher:
Release Date : 1988

Selective Sample Handling And Detection In High Performance Liquid Chromatography

DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1989

Selective Sample Handling And Detection In High Performance Liquid Chromatography written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with categories.

Advanced Chromatographic And Electromigration Methods In Biosciences

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Author : I. Mikšík
language : en
Publisher: Elsevier
Release Date : 1998-09-28

Advanced Chromatographic And Electromigration Methods In Biosciences written by I. Mikšík and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-09-28 with Science categories.

This book deals with chromatographic and electrophoretic methods applied for the separation (quantitation and identification) of biologically relevant compounds. It is assumed that the potential reader is familiar with the basics of chromatographic and electromigration methods. Individual separation modes are dealt with to an extent which follows their applicability for biomedical purposes: liquid chromatography and electromigration methods are therefore highlighted.Each chapter is completed with a list of recent literature covering the 1987-1997 period, which can be used for further guidance of the reader in his/her own field. The chapters have been written by specialists in a particular area and with an emphasis on applications to the biomedical field. This implies that theoretical and instrumental aspects are kept to a minimum which allows the reader to understand the text. Considerable attention is paid to method selection, detection and derivatization procedures and troubleshooting. The majority of examples given represent the analyses of typical naturally-occurring mixtures. Adequate attention is paid to the role of the biological matrix and sample pretreatment, and special attention is given to forensic, toxicological and clinical applications. The book is completed with an extensive Index of Compounds Separated.

Analytical Methods For Major And Modified Nucleosides Hplc Gc Ms Nmr Uv And Ft Ir

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Author :
language : en
Publisher: Elsevier
Release Date : 1989-12-13

Analytical Methods For Major And Modified Nucleosides Hplc Gc Ms Nmr Uv And Ft Ir written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-12-13 with Science categories.

Analytical Methods for Major and Modified Nucleosides - HPLC, GC, MS, NMR, UV and FT-IR

Retention And Selectivity In Liquid Chromatography

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Author : R.M. Smith
language : en
Publisher: Elsevier
Release Date : 1995-01-13

Retention And Selectivity In Liquid Chromatography written by R.M. Smith and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-01-13 with Science categories.

This book brings together a number of studies which examine the ways in which the retention and selectivity of separations in high-performance liquid chromatography are dependent on the chemical structure of the analytes and the properties of the stationary and mobile phases. Although previous authors have described the optimisation of separations by alteration of the mobile phase, little emphasis has previously been reported of the influence of the structure and properties of the analyte.The initial chapters describe methods based on retention index group increments and log P increments for the prediction of the retention of analytes and the ways in which these factors are influenced by mobile phases and intramolecular interactions. The values of a wide range of group increments in different eluents are tabulated.Different scales of retention indices in liquid chromatography are described for the comparison of separations, the identification of analytes and the comparison of stationary phases. Applications of these methods in the pharmaceutical, toxicology, forensic, metabolism, environmental, food and other fields are reviewed. The effects of different mobile phases on the selectivity of the retention indices are reported. A compilation of sources of reported retention index values are given.Methods for the comparison of stationary phases based on the interactions of different analytes are covered, including lipophilic and polar indices, shape selectivity comparisons, their application to novel stationary phases, and chemometric methods for column comparisons.

Electrochemical Detection In Hplc

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Author : Robert J Flanagan
language : en
Publisher: Royal Society of Chemistry
Release Date : 2007-10-31

Electrochemical Detection In Hplc written by Robert J Flanagan and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-31 with Science categories.

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas. The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs. The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

Handbook Of Hplc

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Author : Danilo Corradini
language : en
Publisher: CRC Press
Release Date : 2011-01-03

Handbook Of Hplc written by Danilo Corradini and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-03 with Science categories.

Delineating its usage in separation, purification and detection processes across a variety of disciplines, from industry to applied research, this work discusses the principles, techniques and instrumentation involving HPLC within a detailed framework. Over 100 tables present previously scattered experimental data.

Selective Sample Handling And Detection In High Performance Liquid Chromatography

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