Selenoprotein Structure And Function

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Selenoprotein Structure And Function
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Author :
language : en
Publisher: Academic Press
Release Date : 2022-01-28
Selenoprotein Structure And Function written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-28 with Science categories.
Selenoprotein Structure and Function, Volume 662 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Identification of Selenoprotein O substrates using a biotinylated ATP analog, Selenium-encoded isotopic signature targeted profiling, Designing tRNASec variants for efficient selenocysteine incorporation using Sec-specific reporters, Preparation of selenoprotein S by chemical ligation, Examining xCT-mediated selenium uptake and selenoprotein production capacity in cells, SecMS analysis of selenoprotein with selenocysteine insertion sequence and beyond, Selenocysteine substitutions in thiyl radical enzymes, and much more. Additional chapters cover Recombinant selenoprotein expression in E. coli based upon the redefinition of a UAG codon in an RF1-depleted host strain, Metabolic labeling with radioactive selenium in zebrafish, Low pH isoTOP-ABPP to identify selenocysteines, Expression of selenoproteins via genetic code expansion in mammalian cells, Alpha-methyl selenocysteine as a tool for the study of selenoproteins, Selective selenol fluorescent probes: design, synthesis, structural determinants, and biological applications, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Updated release includes the latest information on Selenoprotein Structure and Function
Selenium And Selenoproteins In Brain Development Function And Disease
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Author : Matthew William Pitts
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-18
Selenium And Selenoproteins In Brain Development Function And Disease written by Matthew William Pitts and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-18 with Science categories.
Archaeal Ribosomes Biogenesis Structure And Function
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Author : Paola Londei
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-24
Archaeal Ribosomes Biogenesis Structure And Function written by Paola Londei and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-24 with Science categories.
Selenoproteins And Mimics
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Author : Junqiu Liu
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-03-30
Selenoproteins And Mimics written by Junqiu Liu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-30 with Science categories.
Selenium has a long history of association with human health and disease. This essential trace element exerts its important biological role in selenoproteins. "Selenoproteins and Mimics" presents the latest developments in selenoproteins, their functional imitation by biomimetic chemistry and biology, and their relationship with human health and diseases. This book provides both the basic biology and biochemistry knowledge of selenoproteins, and sophisticated approaches for the development of new selenoprotein mimics. It's a valuable reference for researchers in biological technology, chemical syntheses, and medicine design. Junqiu Liu is a professor at the State Key Lab of Supramolecular Structure and Materials, Jilin University, China. Guimin Luo is a professor at the Key Lab of Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, China.Ying Mu is a professor at the State Key Lab of Industrial Control Technology, Zhejiang University, and guest professor at the Key Lab of Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, China.
Diversity Of Selenium Functions In Health And Disease
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Author : Regina Brigelius-Flohe
language : en
Publisher: CRC Press
Release Date : 2015-08-14
Diversity Of Selenium Functions In Health And Disease written by Regina Brigelius-Flohe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-14 with Medical categories.
Named after Selene, Greek goddess of the moon, selenium (Se) has moved has moved from being thought of as a toxicant to being considered an essential nutrient with the potential to reduce cancer risk in the span of seven decades. Diversity of Selenium Functions in Health and Disease focuses on current knowledge of aspects of Se research relevant to
Structural And Functional Aspects Of Enzyme Catalysis
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Author : H. Eggerer
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Structural And Functional Aspects Of Enzyme Catalysis written by H. Eggerer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Enzymes perform the executive role in growth, energy conversion, and repair of a living organism. Their activity is adjusted to their en vironment within the cell, being turned off, switched on, or finely tuned by specific metabolites according to demands at the physiologi cal level. Each enzyme discovered in the long history of enzymology has revealed its own individuality. Even closely related members of a family differ in specificity, stability or regulatory properties. Despite these, at first sight overwhelming aspects of individuality, common factors of enzymic reactions have been recognized. Enzymes are stereospecific catalysts even when a nonspecific process would yield the same product. Knowledge of the detailed stereochemistry of an enzymic reaction helps to deduce reaction mechanisms and to ob tain insight into the specific binding of substrates at the active site. This binding close to catalytically competent groups is related to the enormous speed of enzyme-catalyzed reactions. The physical ba sis of rate-enhancement is understood in principle and further exploit ed in the design of small organic receptor molecules as model enzymes. These aspects of enzyme catalysis are discussed in Session 1. Session 2 emphasizes the dynamic aspects of enzyme substrate inter action. Substrate must diffuse from solution space to the enzyme's surface. This process is influenced and can be greatly facilitated by certain electrostatic propterties of enzymes. The dynamic events during catalysis are studied by relaxation kinetics or NMR techniques.
Rna Structure And Function
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Author : Robert W. Simons
language : en
Publisher:
Release Date : 1998
Rna Structure And Function written by Robert W. Simons and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.
The striking functional versatility of RNA is attributable to its remarkable capacity for conformational change. Current models of RNA synthesis, its maturation, translation and degradation are all based on specific structures and there is growing appreciation of the functional importance of interactions between RNA and RNA-binding proteins. This work identifies the major intellectual and technical advances in understanding the part played by structure in how RNA works. It encompasses the experimental approaches used to define RNA structure and its influence on RNA functions such as transcription termination, catalysis, recoding and translational control. Investigators with these interests and students of molecular biology should find this volume a provocative survey of a rapidly-advancing field and a valuable complement to the monograph, The RNA World.
Structural And Functional Relationships In Prokaryotes
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Author : Larry L Barton
language : en
Publisher: Springer Nature
Release Date : 2025-07-29
Structural And Functional Relationships In Prokaryotes written by Larry L Barton and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-29 with Science categories.
This book is designed to be used as textbook for advanced undergraduate and graduate students in courses of microbial physiology and biochemistry, with a specific focus on the physiological processes in bacteria and archaea. This emphasis provides for the basis to explore bacterial and archaeal growth, as well as the response of these cells to the environment and to evaluate the enzymology used to support life at the cellular level. Building on the success of the first edition, the topics have been strengthened by the addition of new information and a reorganization which has resulted in condensed chapters to enable instructors to more readily adapt the various units of this book to their class schedules. A set of questions is provided for each chapter and these questions can serve as in-class discussions or homework projects. Through an extensive use of references, the reader is able to readily identify the source for material presented and this approach enables the book to also serve as a reference for research scientists. Through the use of updated figures and tables, details in the text are provided for the reader. It is the hope that this book will summarize the current understanding of structure-function relationships in prokaryotes and to serve as a bridge to future developments in this area of microbiology.
Mineral Containing Proteins
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Author : Guanghua Zhao
language : en
Publisher: Springer
Release Date : 2017-03-03
Mineral Containing Proteins written by Guanghua Zhao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-03 with Technology & Engineering categories.
This book describes the structure, function and nutritional values of iron-, zinc-, selenium- and calcium-containing proteins, exploring key mineral-containing proteins like phytoferritin and lactoferrin, as well as a host of zinc- and selenium-containing proteins. Due to their role in numerous metabolic processes, minerals such as calcium, iron, zinc and selenium are vital, and have to be obtained from a balanced diet because they cannot be synthesized. The structure and function of mineral-containing proteins influences the absorption of these essential minerals. As such, the study of these proteins is crucial for the assessment and maintenance of a balanced diet and for the development of effective mineral supplements. The book’s closing chapters focus on issues arising from current food processing techniques and in the development of mineral supplements. The book offers a valuable guide for researchers and students in the fields of food chemistry and nutrition.
The Role Of Selenium In Health And Disease
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Author : Catherine Méplan
language : en
Publisher: MDPI
Release Date : 2020-12-06
The Role Of Selenium In Health And Disease written by Catherine Méplan and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-06 with Science categories.
“Role of selenium in health and disease”. This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and human health and disease. Taken together, these articles strengthen the evidence showing that selenium, as a constituent of selenoproteins, is central to biological stress responses and mechanisms commonly altered in most complex disorders. Relevant to public health concerns, this book also emphasizes the U-shaped dose-response relationship between selenium concentration and disease risk across diverse populations from Europe [articles 2,3,6], the Middle East and North Africa [9], and Taiwan [5]. This highlights the importance of personalized nutrition strategies targeted at individuals with increased risk of disease and low selenium intake. The mechanisms by which selenium status, selenoprotein expression, and inherited genetic variations in the selenium pathway interact to affect molecular pathways involved in disease development are explored in human cohorts [2,3,5-7], and in animal [4] and in vitro models [8]. Furthermore, some reports identified novel potential biomarkers of disease risk and prognosis within the selenium pathway that could further our understanding of many chronic diseases [2,3]. Overall, this book broadens our understanding of the role of selenium in chronic diseases, and provides new directions for future preventative approaches.