Diversity Of Selenium Functions In Health And Disease

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Diversity Of Selenium Functions In Health And Disease
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Author : Regina Brigelius-Flohe
language : en
Publisher: CRC Press
Release Date : 2015-08-14
Diversity Of Selenium Functions In Health And Disease written by Regina Brigelius-Flohe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-14 with Medical categories.
Named after Selene, Greek goddess of the moon, selenium (Se) has moved has moved from being thought of as a toxicant to being considered an essential nutrient with the potential to reduce cancer risk in the span of seven decades. Diversity of Selenium Functions in Health and Disease focuses on current knowledge of aspects of Se research relevant to
Diversity Of Selenium Functions In Health And Disease
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Author : Regina Brigelius-Flohe
language : en
Publisher: CRC Press
Release Date : 2015-08-14
Diversity Of Selenium Functions In Health And Disease written by Regina Brigelius-Flohe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-14 with Medical categories.
Named after Selene, Greek goddess of the moon, selenium (Se) has moved has moved from being thought of as a toxicant to being considered an essential nutrient with the potential to reduce cancer risk in the span of seven decades. Diversity of Selenium Functions in Health and Disease focuses on current knowledge of aspects of Se research relevant to
Proteostasis And Proteolysis
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Author : Niki Chondrogianni
language : en
Publisher: CRC Press
Release Date : 2021-11-30
Proteostasis And Proteolysis written by Niki Chondrogianni and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-30 with Science categories.
Proteostasis integrates biological pathways controlling biogenesis, trafficking, folding, and degradation of proteins. This book focuses on two protein breakdown/degradation processes (proteolysis), which are part of a normally functioning proteostatic system: the ubiquitin-proteasome system and autophagy. Chapter 2 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.
Molecular Genetic And Nutritional Aspects Of Major And Trace Minerals
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Author : James F Collins
language : en
Publisher: Academic Press
Release Date : 2016-09-14
Molecular Genetic And Nutritional Aspects Of Major And Trace Minerals written by James F Collins and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-14 with Health & Fitness categories.
Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals is a unique reference that provides a complete overview of the non-vitamin micronutrients, including calcium, copper, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, sodium, and zinc. In addition, the book covers the nutritional and toxicological properties of nonessential minerals chromium, fluoride and boron, and silicon and vanadium, as well as ultra-trace minerals and those with no established dietary requirement for humans. Users will find in-depth chapters on each essential mineral and mineral metabolism, along with discussions of dietary recommendations in the United States and around the world. - Presents the only scientific reference to cover all of the nutritionally relevant essential major and trace minerals - Provides a broad introductory chapter on each mineral to give readers valuable background and context - Clarifies the cellular and molecular aspects of each mineral and its genetic and genomic aspects - Includes coverage of all nutritionally relevant minerals—essential major trace minerals and ultra-trace minerals - Underscores the important interactions between minerals so readers learn how metabolism of one mineral influences another
Selenium
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Author : Bernhard Michalke
language : en
Publisher: Springer
Release Date : 2018-10-24
Selenium written by Bernhard Michalke and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-24 with Medical categories.
This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more. A special focus will be placed on in-depth knowledge about gene expression, selenoprotein biosynthesis, seleno-metabolism--as well as the molecular pathways, physiological roles, and the molecular action of selenium including interaction with other elements and vitamins or as Se-nanoparticles. The reader will receive the newest information regarding redox status and redox regulatory systems, specifically in relation to different glutathione peroxidases and thioredoxin-reductases as well as about cellular bioavailability and cytotoxicity, de-balanced immune response, inflammation or dietary aspects.
Redox Regulation Of Differentiation And De Differentiation
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Author : Carsten Berndt
language : en
Publisher: CRC Press
Release Date : 2021-08-26
Redox Regulation Of Differentiation And De Differentiation written by Carsten Berndt and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-26 with Science categories.
Cell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox modifications are established as important regulatory events in cellular functions including differentiation and development. Redox modifications of single cysteines regulate differentiation of stem cells, formation of functioning organs, and de-differentiation such as formation of cancer cells. Current cancer therapy is based on redox events as well and regeneration often reactivates developmental pathways. Understanding differentiation and de-differentiation on a molecular level is therefore a prerequisite for the continuing development of new medical therapies. This book summarizes the roles of redox regulation in development by bringing together different concepts and comparing similarities and differences between various cell types and species. An international team of contributors presents several new aspects of redox-regulated differentiation and de-differentiation, including aspects of redox medicine. Key Features Provides the first summary on this important topic Reviews redox-dependent development of model organisms and single organs Highlights the redox-regulated pathways important for differentiation processes Illustrates the potential of redox medicine Combines state-of-the-art knowledge in differentiation/development, aging/longevity, and repair/regeneration Written by leading experts in the field Related Titles Ayyanathan, K., ed. Cancer Cell Signaling: Targeting Signaling Pathways Toward Therapeutic Approaches to Cancer (ISBN 978-1-77188-067-1) Clarke, M. & J. Frampton. Stem Cells: Biology and Application (ISBN 9780-8153-4511-4) Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Wong, E., ed. Autophagy and Signaling (ISBN 978-0-367-65772-7)
The Biology Of The First 1 000 Days
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Author : Crystal D Karakochuk
language : en
Publisher: CRC Press
Release Date : 2017-09-22
The Biology Of The First 1 000 Days written by Crystal D Karakochuk and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-22 with Medical categories.
The first 1,000 days, from conception to two years of age, is a critical period of growth and development. Exposures to dietary, environmental, hormonal, and other stressors during this window have been associated with an increased risk of poor health outcomes, some of which are irreversible. The book addresses this crucial interval of early life across biological disciplines, linking concepts related to all biological fields to outcomes during the first 1,000 days (e.g. fetal growth and pregnancy outcomes) and beyond (e.g. gut microbiome and cardiovascular disease later in life). The strength of this book lies in its cross-disciplinary nature.
Nutrition And Cancer Prevention
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Author : Thomas Prates Ong
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-11-27
Nutrition And Cancer Prevention written by Thomas Prates Ong and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-27 with Medical categories.
Cancer is a major global public health problem. Among different environmental and lifestyle factors contributing to cancer risk, diet is a key one. On the one hand, obesity and increased consumption of red and processed meat, ethanol, sugar and saturated fatty acids are associated with increased cancer risk. On the other hand, consumption of micronutrients such as vitamin D, selenium, zinc, folate and bioactive compounds from fruits and vegetables is associated with decreased risk. Written by an influential, international team of experts, this book presents and discusses current topics on nutrition and cancer prevention. It covers both nutritional influences on different cancers plus specific chapters on the commonly occurring cancers. Nutritional genomics-based studies show that some dietary components modulate carcinogenesis through complex cellular and molecular mechanisms. A better understanding of these different cellular and molecular mechanisms is needed to establish efficient dietary recommendations for cancer prevention. This book will provide such an understanding, serving as an important book for all those working in nutritional health, food science and cancer research.
Glutathione
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Author : Leopold Flohe
language : en
Publisher: CRC Press
Release Date : 2018-08-29
Glutathione written by Leopold Flohe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-29 with Medical categories.
This is the first serious attempt to synthesize all that became known of glutathione over the last three decades. The book contains an update of glutathione biosynthesis with special emphasis on its regulation in adaptive stress responses. Other chapters review glutathione transport systems and glutathione peroxidases and their differences in substrate specificities and localization. Further contributions center on the diversified roles of different glutathione-S-transferases and the roles of nitrosoglutathione and glutaredoxins - a subfamily of redoxins. The book closes with discussions of the analogous or homologous thiol metabolism in pathogens and the potential suitability of involved enzymes as drug targets. Key selling features: Summarizing the way glutathione is involved in stress responses Compiling the multiple ways glutathione affects inflammatory responses Disclosing how glutathione dampens programmed cell death such as ferroptosis Exploring the enigma of how enzymes accelerate glutathione-dependent processes Discussing how detoxification and redox regulation is mediated by glutathionylation Reviewing the ways glutaredoxins catalyze protein disulfide reduction Highlighting the medical impact of glutathione-related metabolic pathways Illustrating the role thiol metabolism of pathogens might play in drug discovery Chapter 11 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution (CC-BY) 4.0 license.
Mitochondria In Liver Disease
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Author : Derick Han
language : en
Publisher: CRC Press
Release Date : 2015-10-28
Mitochondria In Liver Disease written by Derick Han and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-28 with Medical categories.
" excellent, well-organized, and timely."-Lester Packer and Enrique Cardenas, University of Southern California, Los Angeles, from the Series PrefaceThe liver is a vital organ that is responsible for a wide range of functions, most of which are essential for survival. The multitude of functions the liver performs makes it vulnerable to a wide range