Self Reactive Polyspecific Iga Antibodies In Vomitoxin Induced Glomerulonephritis
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Self Reactive Polyspecific Iga Antibodies In Vomitoxin Induced Glomerulonephritis
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Author : Linda Rasooly
language : en
Publisher:
Release Date : 1992
Self Reactive Polyspecific Iga Antibodies In Vomitoxin Induced Glomerulonephritis written by Linda Rasooly and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with IgA glomerulonephritis categories.
Nutrition And Immunology
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Author : M. Eric Gershwin
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-11-12
Nutrition And Immunology written by M. Eric Gershwin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-11-12 with Medical categories.
It is a pleasure to write the foreword to Nutrition and Table 1 Nutritional Status and Outcome of Infection Immunology: Principles and Practice. In fact, this book comes at a timely moment, when the impact of nutrition and Definite adverse outcome immunology is being widely felt because of the AIDS epi Measles, diarrhea, tuberculosis demic. This is particularly of note in Africa, where large Probable adverse outcome HIV, malaria, pneumonia sums of money are being spent on nutritional intervention Little or no effect programs in the hopes of improving immune responsive Poliomyelitis, tetanus, viral encephalitis ness. We should not forget, however, early advances in our Note: HIV= human immunodeficiency virus understanding of protein energy malnutrition (PEM). PEM can be used as a model to understand the nutritional basis of immunity, as well as the immunological influences on nutri tional status. Despite advances in agricultural production, tance. However, both in vitro studies and tests in laboratory PEM continues to affect hundreds of millions ofthe world's animals may have little resemblance to what is experienced population. The functional impact of undernutrition varies in humans under field conditions. from mild morbidity to life-threatening infection.
Dissertation Abstracts International
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Author :
language : en
Publisher:
Release Date : 1993-07
Dissertation Abstracts International written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-07 with Dissertations, Academic categories.
Drug Discovery And Evaluation Safety And Pharmacokinetic Assays
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Author : H. Gerhard Vogel
language : en
Publisher: Springer
Release Date : 2013-02-27
Drug Discovery And Evaluation Safety And Pharmacokinetic Assays written by H. Gerhard Vogel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-27 with Medical categories.
-A landmark in the continuously changing world of drugs -Essential reading for scientists and managers in the pharmaceutical industry involved in drug finding, drug development and decision making in the development process -Of use for government institutions and committees working on official guidelines for drug evaluation worldwide
Immunotoxicology And Immunopharmacology
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Author : H Dean Jack
language : en
Publisher: CRC Press
Release Date : 1994-06-30
Immunotoxicology And Immunopharmacology written by H Dean Jack and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-06-30 with Medical categories.
The second edition of this text has been revised and refocused to reflect the transformation of immunotoxicology from a subdiscipline of toxicology to an independent area of research that can best be described as "environmental immunology." New chapters discuss the role of immune mediators in liver, lung, and skin toxicity, in regulating chemical- metabolizing enzymes, and in the immunosuppression produced by ultraviolet light. More emphasis is placed on the clinical consequences of immunotoxicity, as well as the interpretation of experimental data for predicting, human health risk.; The second edition is divided into three major sections: immunosuppression, autoimmunity, and hypersensitivity. This new organization of the text allows for a more thorough treatment of these phenomena, with greater attention to test methods, theoretical considerations, and clinical implications. The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.
Drug Discovery And Evaluation Methods In Clinical Pharmacology
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Author : H.Gerhard Vogel
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-15
Drug Discovery And Evaluation Methods In Clinical Pharmacology written by H.Gerhard Vogel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-15 with Medical categories.
Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Safety Evaluation Of Certain Mycotoxins In Food
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Author : Joint FAO/WHO Expert Committee on Food Additives. Meeting
language : en
Publisher: Food & Agriculture Org.
Release Date : 2001
Safety Evaluation Of Certain Mycotoxins In Food written by Joint FAO/WHO Expert Committee on Food Additives. Meeting and has been published by Food & Agriculture Org. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Aflatoxins categories.
This volume contains monographs prepared at the fifty-sixth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). Five mycotoxins or groups of mycotoxins that contaminate food commodities were evaluated at the meeting: aflatoxin M1, fumonisins B1, B2, and B3, ochratoxin A, deoxynivalenol, and T -2 and HT -2 toxins. The monographs in this volume summarize the data that were reviewed on these contaminants, including information on metabolism and toxicity, epidemiology, analytical methods for their measurement in food commodities, sampling protocols, effects of processing, levels and patterns of contamination of food commodities, food consumption, and prevention and control. Based upon this information the Committee assessed the risks associated with intake of these mycotoxins.
Fusarium Species
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Author : Abraham Z. Joffe
language : en
Publisher: Wiley-Interscience
Release Date : 1986-08-14
Fusarium Species written by Abraham Z. Joffe and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-08-14 with Medical categories.
This clear, in-depth guide describes the Fusarium genus and its toxins--a widespread group of plant pathogens associated with disease and sometimes death in humans and livestock and implicated as the active agent in ``yellow rain.'' Noted authority Abraham Joffe presents new and original research into the biology of the Fusarium and the chemistry, biochemical and toxicological properties of their toxins.
Drug Discovery And Evaluation
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Author : Hans G. Vogel
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Drug Discovery And Evaluation written by Hans G. Vogel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.
This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals.
Alphaherpesviruses
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Author : Sandra Knowles Weller
language : en
Publisher: Caister Academic Press Limited
Release Date : 2011
Alphaherpesviruses written by Sandra Knowles Weller and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.