Separation Methods In Drug Synthesis And Purification
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Separation Methods In Drug Synthesis And Purification
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Author : Klara Valko
language : en
Publisher: Elsevier
Release Date : 2000-10-13
Separation Methods In Drug Synthesis And Purification written by Klara Valko and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-10-13 with Science categories.
Separation Methods in Drug Synthesis and Purification
Separation Methods In Drug Synthesis And Purification
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Author : Klara Valko
language : en
Publisher: Elsevier
Release Date : 2020-06-19
Separation Methods In Drug Synthesis And Purification written by Klara Valko and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-19 with Science categories.
Separation Methods in Drug Synthesis and Purification, Second Edition, Volume Eight, provides an updated on the analytical techniques used in drug synthesis and purification. Unlike other books on either separation science or drug synthesis, this volume combines the two to explain the basic principles and comparisons of each separation technique. New sections to this volume include enantiomer separation using capillary electrophoresis (CE) and capillary electro- chromatography, the computer simulation of chromatographic separation for accelerating method development, the application of chromatography and capillary electrophoresis used as surrogates for biological processes, and new developments in the established techniques of chromatography and preparative methods. - Features descriptions and applications of all separation methods used in the pharmaceutical industry - Written by the leading scientists in their respective fields, providing solutions for a wide range of industrial separation problems encountered within the pharmaceutical industry - Thoroughly updated with brand new separation science techniques and the latest developments in the established techniques of chromatography
Chiral Separation Methods For Pharmaceutical And Biotechnological Products
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Author : Satinder Ahuja
language : en
Publisher: John Wiley & Sons
Release Date : 2011-03-31
Chiral Separation Methods For Pharmaceutical And Biotechnological Products written by Satinder Ahuja and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-31 with Science categories.
Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.
Physicochemical And Biomimetic Properties In Drug Discovery
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Author : Klara Valko
language : en
Publisher: John Wiley & Sons
Release Date : 2013-11-25
Physicochemical And Biomimetic Properties In Drug Discovery written by Klara Valko and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-25 with Medical categories.
Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization, Physicochemical and Biomimetic Properties in Drug Discovery encourages readers to discover relationships between various measurements and develop a sense of interdisciplinary thinking that will add to new research in drug discovery. This practical guide includes detailed descriptions of state-of-the-art chromatographic techniques and uses real-life examples and models to help medicinal chemists and scientists and advanced graduate students apply measurement data for optimal drug discovery.
Physico Chemical Methods In Drug Discovery And Development
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Author : Zoran Mandic
language : en
Publisher: IAPC Publishing
Release Date : 2012
Physico Chemical Methods In Drug Discovery And Development written by Zoran Mandic and has been published by IAPC Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
Separations Chemistry
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Author : Fedor Macášek
language : en
Publisher: Xlibris Corporation
Release Date : 2016-06-06
Separations Chemistry written by Fedor Macášek and has been published by Xlibris Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-06 with Science categories.
Separation of chemical species is a gate to final success of synthesis and preparation of compounds in pure and defined state. Variability of natural and artificial mixtures to be treated is enormous. Task of chemistry is to separate components of homogeneous mixtures (the gaseous and liquid solutions). The book concentrates on understanding the basic philosophies of both equilibrium and nonequilibrium chemical thermodynamics and engineering performance that lay in principle of separation technique such as distillation, crystallization, centrifugation, sorption, membrane separations, chromatography, and liquid-liquid extraction. Specific phenomena connected with photochemical separation, isotope composition, and radioactivity are discussed as well. The book is written for advanced students of chemistry having the knowledge of physical chemistry. Calculation examples are based on the international system of units. Unique list of over 1,300 full references covers scientific literature of the eighteenth to the twenty-first centuries.
Chiral Separations By Liquid Chromatography And Related Technologies
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Author : Hassan Y. Aboul-Enein
language : en
Publisher: CRC Press
Release Date : 2003-06-03
Chiral Separations By Liquid Chromatography And Related Technologies written by Hassan Y. Aboul-Enein and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-03 with Science categories.
Unique in its systematic and detailed description of the various types, structures, and properties of chiral stationary phases (CSPs) and their preparation, application, and future scope, this volume highlights an assortment of liquid chromatographic approaches, including sub- and super-critical fluid chromatography, capillary electrochromatography
New Generation Green Solvents For Separation And Preconcentration Of Organic And Inorganic Species
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Author : Mustafa Soylak
language : en
Publisher: Elsevier
Release Date : 2020-04-07
New Generation Green Solvents For Separation And Preconcentration Of Organic And Inorganic Species written by Mustafa Soylak and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-07 with Science categories.
New Generation Green Solvents for Separation and Preconcentration of Organic and Inorganic Species is designed to help researchers and students understand the production and application of new generation green solvents in separation- and preconcentration-based analytical methods. Beginning with the historical background and milestones in the development of analytical instrumentation, the book goes on to give a detailed overview of the most up-to-date uses of green solvents in sample preparation. Using a wealth of examples, it compares old and new extraction procedures and explores the many applications of new generation green solvents. Practical, easy-to-follow experiments are used to illustrate the key concepts. This practical guide helps to promote the use of safer, more sustainable solvents in analytical chemistry and beyond for environmental scientists, researchers in pharmaceutical and biotech industries, and students in analytical chemistry. - Covers the basic analytical theory essential for understanding extraction- and microextraction-based separation and preconcentration methods - Explains combination use of new generation solvents with various detection systems, including UV-VIS, ICP-MS, HPLC, LC-MS, GC-MS, and LC-MS/MS - Emphasizes trace chemical component separation, preconcentration and analysis
Chiral Separation Techniques
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Author : Ganapathy Subramanian
language : en
Publisher: John Wiley & Sons
Release Date : 2008-01-08
Chiral Separation Techniques written by Ganapathy Subramanian and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-08 with Science categories.
Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.
Chemometric Methods In Capillary Electrophoresis
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Author : Grady Hanrahan
language : en
Publisher: John Wiley & Sons
Release Date : 2009-10-22
Chemometric Methods In Capillary Electrophoresis written by Grady Hanrahan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-22 with Science categories.
Use chemometric techniques to develop optimum separation conditions for capillary electrophoreses For all its advantages, capillary electrophoresis (CE) also carries significant disadvantages for the researcher. Offering a unique blend of information from authors active in a variety of developments of chemometrics in CE, Chemometric Methods in Capillary Electrophoresis presents modern chemometric methods as an alternative to help alleviate the problems commonly encountered during routine analysis and method development. Focusing on current chemometric methods utilized in CE endeavours by research-active experts in the field, the book begins with a thorough introduction to CE and chemometric-related concepts and the need for modern chemometric methods in CE. Part 1 discusses differing types of screening designs and response surface methodology¿in an¿application based format Part 2 includes vital discussion on various exploratory data analysis, prediction, and classification techniques utilized in CE-related studies Part 3 provides practical information on modelling quantitative structure relationships Part 4 explores transformation techniques, in particular fundamental studies and applications of cross-correlation and Hadamard Transform Electrophoresis Showing how chemometric methods are applied in a wide array of applications including biological, medical, pharmaceutical, food, forensic, and environmental science, Chemometric Methods in Capillary Electrophoresis is not only highly significant to capillary electrophoresis-based endeavours, but instructive for investigators active in other areas of separation science who could benefit from its informative content.