Septic Shock
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Septic Shock
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Author : Jean-François Dhainaut
language : en
Publisher: Bailliere Tindall Limited
Release Date : 2000
Septic Shock written by Jean-François Dhainaut and has been published by Bailliere Tindall Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
A current, authoritative guide to the clinical management of the critically ill septic shock patient. Discusses the benefits and limitations of alternative management strategies. Identifies key clinical problems to be addressed, and assigns the correct priority to each problem in a step-by-step manner. Checklists and algorithms are provided as appropriate.
Septic Shock
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Author : George H. Sakorafas
language : en
Publisher: Nova Publishers
Release Date : 2005
Septic Shock written by George H. Sakorafas and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Septic shock categories.
Sepsis is one of the most frequent complications in the surgical patient and one of the leading causes of mortality in intensive care units. During the past two decades, a great deal has been learned about surgical bacteriology, antibiotic prophylaxis, supportive management, and the host response to microbial invasion. Sepsis can be caused by infection with gram-negative bacteria, gram-positive bacteria, fungi (and particularly Candida), or viruses. Sepsis may also occur in the absence of detectable bacterial invasion, and in these cases, microbial toxins, particularly gram-negative bacterial endotoxin (lipopolysaccharide, LPS), and endogenous cytokine production have been implicated as initiators and mediators. Although activation of the immune system during microbial invasion is generally protective, septic shock develops in a significant number of patients as a consequence of a poorly regulated immune response to the offending organism. Sepsis can be presented with a spectrum of severity. Septic shock represents the most severe form of host response to infection. The aim of this monograph is to summarise the currently available data regarding epidemiology, pathogenesis, and optimal management of septic shock, with a particular emphasis on the role of source control in sepsis. Emerging therapies for septic shock are also discussed.
Evolving Concepts In Sepsis And Septic Shock
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Author : Peter Q. Eichacker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Evolving Concepts In Sepsis And Septic Shock written by Peter Q. Eichacker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically to augment our conventional antimicrobial and supportive therapies during sepsis with agents modulating the inflammatory response have been unsuccessful. As a result, the mortality associated with this lethal syndrome, especially when complicated by shock, has remained persistently high. Unfortunately, during this same period of time, the incidence of sepsis has accelerated as other fields of medicine have relied increasingly on therapies that predispose to infection. While frustrating, overall this experience in the field of sepsis has not been without value. Most importantly, it has helped define on several different levels the complexity of the septic patient. Recognizing and addressing this complexity as discussed by each of the contributors to Evolving Concepts in Sepsis and Septic Shock may now provide new inroads into the treatment of sepsis.
Septic Shock Methods And Protocols
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Author : Thomas J. Evans
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01
Septic Shock Methods And Protocols written by Thomas J. Evans and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Medical categories.
Septic shock remains a serious medical condition with high mortality. Despite many advances in intensive care medicine and antibiotic devel- ment, this has not changed appreciably in the last 20 years. Frustratingly, over the same period of time, enormous advances have been made in understa- ing the underlying pathogenic mechanisms of this condition. This has resulted in the development of several novel therapies for septic shock, which, despite excellent theoretical grounds for their efficacy, have failed in altering mort- ity attributable to sepsis. The reasons for these failures are multiple, but it is clear that further research is required aimed at increasing our understanding of the basic pat- physiological processes that occur following infection. Research into septic shock draws upon a number of different disciplines, ranging from molecular and cellular biology to physiological measurements on whole animals. Septic Shock Methods and Protocols is an attempt to draw together into one volume a number of protocols that are of use in the investigation of the mechanisms of septic shock. I have divided the book into five sections. The first deals with endotoxin, the lipopolysaccharide component of the Gram-negative cell m- brane that can mimic many of the features of septic shock. Gram-positive organisms are found increasingly as causes of septic shock, and several - pects of toxins produced from these bacteria are considered in the second s- tion.
Septic Shock
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Author : Melvin C. Johnston
language : en
Publisher: Nova Science Publishers
Release Date : 2013-07
Septic Shock written by Melvin C. Johnston and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07 with Septic shock categories.
Septic shock is a common and lethal condition that remains one of the leading causes of death in the hospital. Greater awareness, understanding of the condition and knowledge of effective management may decrease the mortality rate. In this book, the authors discuss the symptoms, management and risk factors of septic shock. Topics include the pathophysiology of cardiovascular failure in septic shock; life threatening infections and septic shock during idiopathic drug-induced agranulocytosis; the role of HMGB1 in cardiac dysfunction during septic shock; the epidemiological impact of sepsis and septic shock; and possible implications for the treatment of septic patients with interventions aimed at opening microcirculation.
Sepsis And Septic Shock An Issue Of Critical Care Clinics
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Author : Claudia Lance
language : en
Publisher: American Medical Publishers
Release Date : 2021-11-16
Sepsis And Septic Shock An Issue Of Critical Care Clinics written by Claudia Lance and has been published by American Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Medical categories.
Shock is caused by the decreased flow of blood to the body tissues due to circulatory system related problems. Sepsis refers to a life-threatening condition where the body causes injury to its own organs and tissues in response to an infection. When sepsis lowers the blood pressure to the extent where it does not improve after fluid replacement, it is known as septic shock. Sepsis happens due to an inflammatory immune response which is triggered by an infection. Septic shock is usually caused by bacteria but it can also be caused by fungi, parasites or viruses. It generally affects the lungs, urinary tract, brain or skin. Fever, increased breathing and heart rate, and confusion are some of its common signs and symptoms. Severe sepsis results in organ dysfunction and poor blood flow. This book provides significant information to help develop a good understanding of sepsis and septic shock. Different approaches, evaluations, methodologies and advanced studies have been included herein. Those in search of information to further their knowledge will be greatly assisted by this book.
Septic Shock
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Author : Benedict Graver
language : en
Publisher: Nova Science Publishers
Release Date : 2015
Septic Shock written by Benedict Graver and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Septic shock categories.
In a 2013 Healthcare Cost and Utilization Project Statistical Brief by the US Agency for Healthcare Research and Quality, septicemia was ranked as the number one most expensive national inpatient hospital cost. This ranking comes in spite of substantial advances in the clinical management of sepsis over the past fifteen years. While adherence with internationally established sepsis management protocols have demonstrated reduction in mortality and hospital/ICU length of stay, compliance with these protocols remains poor. This book discusses risk factors, management and prognosis of septic shock in individuals.
Pathophysiology Of Shock Sepsis And Organ Failure
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Author : Günther Schlag
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Pathophysiology Of Shock Sepsis And Organ Failure written by Günther Schlag and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In this book current knowledge of the pathophysiology of shock, sepsis and multi organ failure is presented. The rapid progress which has been made and the results achieved in intensive care medicine are based on sound basic research, which is duly reflected in these chapters. Multiorgan failure is the foremost cause of postoperative and posttraumatic death and many complex mechanisms are involved. Only with a good foundation of basic research can abnormalities in the physiological, biochemical, and morphological course of shock be recognized and the necessary conclusions for treatment drawn. Therapy must proceed from profound knowledge of the multi variant physiological events in order to influence shock, sepsis and organ failure. Although numerous possibilities for therapy have arisen from pharmaceutical research in recent years, they are beyond the scope of this book and are not discussed here. To gain a better understanding of the pathophysiological events it was necessary to examine and to describe different models that simulate and reproduce these events. Here we describe the causative agents (shock) and the consequences (sepsis, organ failure) in two main sections, divided on the basis of their pathophysiology.
Handbook Of Mediators In Septic Shock
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Author : Edmund A. Neugebauer
language : en
Publisher: CRC Press
Release Date : 2019-07-23
Handbook Of Mediators In Septic Shock written by Edmund A. Neugebauer and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-23 with Science categories.
Handbook of Mediators in Septic Shock presents a comprehensive, systematic evaluation of the various putative mediators of septic shock through the use of meta-analysis. Experts of individual mediators have objectively evaluated the collective literature using classical Koch-Dale Criteria for causal relationships. A decision tree approach has been used to analyze the existing evidence for each of the four Koch-Dale Criteria for each individual mediator of septic shock. The book provides an integrated perspective that describes how these many mediators interact. It also covers how advances in mathematical modeling of complex realities are applied to the field of septic shock pathogenesis. CRC Handbook of Mediators in Septic Shock will be a useful reference for emergency room and intensive care physicians, trauma specialists, pathophysiologists, physiologists, biochemists, pharmacologists, and others interested in the topic. Features
Septic Shock In Man
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Author : Solomon George Hershey
language : en
Publisher:
Release Date : 1971
Septic Shock In Man written by Solomon George Hershey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Septic shock categories.