Septic Shock Methods And Protocols

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Septic Shock Methods And Protocols

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Author : Thomas J. Evans
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01

Septic Shock Methods And Protocols written by Thomas J. Evans and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Medical categories.

Septic shock remains a serious medical condition with high mortality. Despite many advances in intensive care medicine and antibiotic devel- ment, this has not changed appreciably in the last 20 years. Frustratingly, over the same period of time, enormous advances have been made in understa- ing the underlying pathogenic mechanisms of this condition. This has resulted in the development of several novel therapies for septic shock, which, despite excellent theoretical grounds for their efficacy, have failed in altering mort- ity attributable to sepsis. The reasons for these failures are multiple, but it is clear that further research is required aimed at increasing our understanding of the basic pat- physiological processes that occur following infection. Research into septic shock draws upon a number of different disciplines, ranging from molecular and cellular biology to physiological measurements on whole animals. Septic Shock Methods and Protocols is an attempt to draw together into one volume a number of protocols that are of use in the investigation of the mechanisms of septic shock. I have divided the book into five sections. The first deals with endotoxin, the lipopolysaccharide component of the Gram-negative cell m- brane that can mimic many of the features of septic shock. Gram-positive organisms are found increasingly as causes of septic shock, and several - pects of toxins produced from these bacteria are considered in the second s- tion.

Molecular Pathology Of The Prions

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Author : Harry F. Baker
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Molecular Pathology Of The Prions written by Harry F. Baker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.

Internationally recognized investigators review the latest developments in, and novel approaches to, understanding the prion protein and prion diseases at the molecular level. Utilizing a variety of cutting-edge techniques, these distinguished scientists seek to define the normal function of a prion protein, to detect and measure the early immune response to prion disease, and to discover possible therapeutic targets. They also use transgenic mice and new electrophysiological investigations to elucidate the pathogenetic mechanisms involved in prion diseases. State-of-the-art and richly insightful, Molecular Pathology of the Prions captures for basic and clinical neuropathologists the latest developments and approaches to understanding the pathogenesis of prion diseases, and by analogy suggests possible research techniques for the more common proteinopthies, such as Alzheimer's and Parkinson's diseases.

Meningococcal Disease

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Author : Andrew J. Pollard
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Meningococcal Disease written by Andrew J. Pollard and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.

Meningococcal septicemia and meningitis continue to be important causes of devastating illness, death, and long-term disability in both developed and resource-poor countries of the world. Few diseases have attracted as much public attention, or are as feared by parents and family members, as well as the medical staff who have to care for affected patients. The unexpected and unp- dictable occurrence of the disease in previously healthy children and young adults, its rapid progression, and the frequent occurrence of purpura fulminans with the resulting gangrene of limbs and digits and the requirement for mutilating s- gery, have all heightened both public and medical interest in the disease. Over the past two decades there has been a rapid increase in knowledge of many aspects of meningococcal disease as a result of intensive efforts by workers in many different fields: clinicians have studied the early presenting features and acute pathophysiology of the disorder; clinical scientists have explored the immunopathological mechanisms responsible for disease and have highlighted the important roles played by the host inflammatory response and pro-inflammatory cytokines in mediating damage to blood vessels and organs; microbiologists have developed new diagnostic methods; public health phy- cians and epidemiologists have improved surveillance techniques with the help of molecular tools provided by bacterial population biologists; and basic sci- tists have used the powerful new tools in molecular and cell biology to elucidate virulence mechanisms.

An Introduction To Clinical Emergency Medicine

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Author : S. V. Mahadevan
language : en
Publisher: Cambridge University Press
Release Date : 2012-04-10

An Introduction To Clinical Emergency Medicine written by S. V. Mahadevan and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-10 with Medical categories.

Fully-updated edition of this award-winning textbook, arranged by presenting complaints with full-color images throughout. For students, residents, and emergency physicians.

Essentials Of Shock Management

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Author : Gil Joon Suh
language : en
Publisher: Springer
Release Date : 2018-11-30

Essentials Of Shock Management written by Gil Joon Suh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-30 with Medical categories.

This book is designed to offer the reader first-rate guidance on shock management in the real world. Comprehensive, evidence-based, and up-to-date instruction is provided on optimal care of patients with different types of shock – septic, hemorrhagic, cardiogenic, anaphylactic, and obstructive – at all stages from initial response through to ICU admission. As well as management, the coverage encompasses pathophysiology, clinical presentation, diagnosis, and emerging trends. A further key feature is the use of a scenario-based approach to present a series of cases based on real-life experiences. Here, a narrative style and Q&A form are employed to vividly convey scenarios that may be encountered in clinical practice and to elucidate decision making in complex circumstances. When readers experience difficulty in answering the questions, the earlier sections can be consulted to identify the correct response. This book will be of great value for all health care professionals. In particular, it will be very helpful for novice or inexperienced practitioners in emergency medicine, critical care medicine, and traumatology.

Molecular Analysis Of Cancer

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Author : Jacqueline Boultwood
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Molecular Analysis Of Cancer written by Jacqueline Boultwood and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.

Over the past 20 years, technological advances in molecular biology have proven invaluable to the understanding of the pathogenesis of human cancer. The application of molecular technology to the study of cancer has not only led to advances in tumor diagnosis, but has also provided markers for the assessment of prognosis and disease progression. The aim of Molecular Ana- sis of Cancer is to provide a comprehensive collection of the most up-to-date techniques for the detection of molecular changes in human cancer. Leading researchers in the field have contributed chapters detailing practical pro- dures for a wide range of state-of-the-art techniques. Molecular Analysis of Cancer includes chapters describing techniques for the identification of chromosomal abnormalities and comprising: fluor- cent in situ hybridization (FISH), spectral karyotyping (SKY), comparative genomic hybridization (CGH), and microsatellite analysis. FISH has a pro- nent role in the molecular analysis of cancer and can be used for the detection of numerical and structural chromosomal abnormalities. The recently described SKY, in which all human metaphase chromosomes are visualized in specific colors, allows for the definition of all chromosomal rearrangements and marker chromosomes in a tumor cell. Protocols for the detection of chromosomal re- rangements by PCR and RT-PCR are described, as well as the technique of DNA fingerprinting, a powerful tool for studying somatic genetic alterations in tumorigenesis.

Understanding Anesthetic Equipment Procedures

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Author : Dwarkadas K Baheti
language : en
Publisher: JP Medical Ltd
Release Date : 2018-03-31

Understanding Anesthetic Equipment Procedures written by Dwarkadas K Baheti and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-31 with Medical categories.

This new edition presents practising and trainee anaesthesiologists with the latest advances and guidelines in their field. Beginning with an introduction to the history of anaesthesia, basic physics, and medical gases, the following sections cover the anaesthesia machine, airway and monitoring equipment, and apparatus for central neuraxial and regional blocks. The final chapters discuss interpretation of radiological images, simulators in anaesthesia, maintenance, safety and cleaning; and more. The second edition has been fully revised to provide up to date information and a clear understanding of practices and techniques for anaesthesia. The book features clinical photographs and diagrams and includes two interactive DVD ROMs demonstrating and explain day to day anaesthetic procedures. Key points Fully revised, new edition presenting latest techniques and information in anaesthesia Covers all different aspects of equipment in depth Includes DVD ROMs demonstrating anaesthetic procedures Previous edition (9789351521242) published in 2014

Cardiopulmonary Physiotherapy In Trauma An Evidence Based Approach Second Edition

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Author : Heleen Van Aswegen
language : en
Publisher: World Scientific
Release Date : 2024-02-06

Cardiopulmonary Physiotherapy In Trauma An Evidence Based Approach Second Edition written by Heleen Van Aswegen and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-06 with Medical categories.

Trauma is a serious public health problem worldwide and is the leading cause of death among adults and children. Physiotherapists play a key role in the interdisciplinary team caring for patients with physical injury after a traumatic event. The aim of Cardiopulmonary Physiotherapy in Trauma: An Evidence-based Approach is to encourage quality evidence-based physiotherapy management of adult and paediatric survivors of trauma in an acute care setting on a global level.The first edition of the book was written by South African physiotherapy academics and clinical physiotherapists with expertise in trauma care. This new edition involves the South African writers from the first edition as well as a team of international experts in trauma care across health care disciplines (including surgeons, nurses, occupational therapists, dieticians, pain experts, and social workers). The information shared in the first edition has therefore been updated with more clinical expertise and the latest available evidence. The new content in this latest edition aims to make physiotherapists more aware of the importance of considering how pain influences patients' participation in therapy sessions, and of a team approach to patient care (e.g. managing pain and planning of care) to ensure the best possible outcomes for adult and paediatric patients with traumatic injury, at hospital discharge.

Aacn Protocols For Practice

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Author : Suzanne M. Burns
language : en
Publisher: Jones & Bartlett Learning
Release Date : 2007

Aacn Protocols For Practice written by Suzanne M. Burns and has been published by Jones & Bartlett Learning this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.

Care of Mechanically Ventilated Patients guides clinicians’ practice in the following categories: airway management, modes and methods of mechanical ventilation, weaning, sedation and neuromuscular blockade, nutrition support, and home care management of ventilator-assisted patients. Each protocol guides clinicians in the appropriate selection of patients, use and application of management principles, initial and ongoing monitoring, discontinuation of therapies or interventions, and selected aspects of quality control.

The Sepsis Codex E Book

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Author : Marcio Borges
language : en
Publisher: Elsevier Health Sciences
Release Date : 2022-11-30

The Sepsis Codex E Book written by Marcio Borges and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-30 with Medical categories.

Offering a global, multidisciplinary perspective on this life-threatening medical emergency, The Sepsis Codex provides a concise yet comprehensive look at a complex topic. Nearly 20% of global deaths are attributed to sepsis annually, nearly half of which are in children under the age of five, with low-resource settings being disproportionately affected. A "one size fits all approach is not sufficient to meet individual patients' needs, instead requiring a therapeutic approach that considers different ages, predisposing factors, genetic traits, and more. This cutting-edge resource brings you up to date with recent medical advances in this challenging area. - Covers pathophysiology, early detection, biomarkers and diagnosis, therapies, controversies, future research, the use of AI, professional organizations and public health in sepsis. - Includes chapters on sepsis in special populations such as in pregnant women, transplanted patients, and children. - Consolidates today's available information on this timely topic into a single, convenient resource.