Sex Differences In The Central Nervous System


Sex Differences In The Central Nervous System
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Sex Differences In The Central Nervous System


Sex Differences In The Central Nervous System
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Author : Rebecca M. Shansky
language : en
Publisher: Academic Press
Release Date : 2015-09-14

Sex Differences In The Central Nervous System written by Rebecca M. Shansky and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-14 with Science categories.


Sex Differences in the Central Nervous System offers a comprehensive examination of the current state of sex differences research, from both the basic science and clinical research perspectives. Given the current NIH directive that funded preclinical research must consider both females and males, this topic is of interest to an increasing percentage of the neuroscience research population. The volume serves as an invaluable resource, offering coverage of a wide range of topics: sex differences in cognition, learning, and memory, sex hormone signaling mechanisms, neuroimmune interactions, epigenetics, social behavior, neurologic disease, psychological disorders, and stress. Discussions of research in both animal models and human patient populations are included. Details how sex hormones have widespread effects on the nervous system and influence the way males and females function Assists readers in determining how sex impacts their research and practice, and assists in determining how to adjust research programs to incorporate sex influences Includes discussions of research in both animal models and human patient populations, and at various developmental stages Features revised and updated chapters by leaders in the field around the globe—the broadest, most expert coverage available



Sex Differences In The Brain


Sex Differences In The Brain
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Author : Jill B. Becker
language : en
Publisher: Oxford University Press
Release Date : 2007-12-04

Sex Differences In The Brain written by Jill B. Becker and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-04 with Medical categories.


Within the basic and clinical biomedical research community, there is increasing recognition that differences between males and females across the lifespan affect an individual's health, his/her development of disease, signs and symptoms of pathophysiology, and response to therapy. This book is intended as a resource for scientists, clinicians, and students of the nervous system and behavior- a trove of practical information about how to study sex differences in the brain as well as a discussion of what is already known on the topic.



Sex And The Developing Brain


Sex And The Developing Brain
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Author : Margaret M. McCarthy
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2011

Sex And The Developing Brain written by Margaret M. McCarthy and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.


The brains of males and females, men and women, are different-that is a fact. What is debated is how different and how important those differences are. Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. The importance of nonbiological variables to sex differences in humans is paramount, making it difficult if not impossible to parse out those contributions that are truly biological. The study of animals provides us the opportunity to understand the magnitude and scope of biologically based sex differences in the brain and understanding the cellular mechanisms provides us insight into novel sources of brain plasticity. Many sex differences are established during a developmental sensitive window by differences in the hormonal milieu of males versus females. The neonatal testis produces large amounts of testosterone, which gains access to the brain and is further metabolized into active androgens and estrogens, which modify brain development. Major parameters that are influenced by hormones include neurogenesis, cell death, neurochemical phenotype, axonal and dendritic growth, and synaptogenesis. Variance in these parameters results in sex differences in the size of particular brain regions, the projections between brain regions, and the number and type of synapses within particular brain regions. The cellular mechanisms are both region and endpoint specific and invoke many surprising systems such as prostaglandins, endocannabinoids, and cell death proteins. By understanding when, why, and how sex differences in the brain are established, we may also learn the source of strong gender biases in the relative risk and severity of numerous neurological diseases and disorders of mental health, including but not limited to autism, dyslexia, attention deficit disorder, schizophrenia, Alzheimer's, multiple sclerosis, Parkinson's, and maj



Sex And The Developing Brain


Sex And The Developing Brain
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Author : Margaret M. McCarthy
language : en
Publisher: Biota Publishing
Release Date : 2017-08-31

Sex And The Developing Brain written by Margaret M. McCarthy and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-31 with Science categories.


The brains of males and females, men and women, are different, that is a fact. What is debated is how different and how important are those differences. Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. The importance of nonbiological variables to sex differences in humans is paramount, making it difficult if not impossible to parse out those contributions that are truly biological. The study of animals provides us the opportunity to understand the magnitude and scope of biologically based sex differences in the brain, and understanding the cellular mechanisms provides us insight into novel sources of brain plasticity. Many sex differences are established during a developmental sensitive window by differences in the hormonal milieu of males versus females. The neonatal testis produces large amounts of testosterone which gains access to the brain and is further metabolized into active androgens and estrogens which modify brain development. Major parameters that are influenced by hormones include neurogenesis, cell death, neurochemical phenotype, axonal and dendritic growth, and synaptogenesis. Variance in these parameters results in sex differences in the size of particular brain regions, the projections between brain regions, and the number and type of synapses within particular brain regions. The cellular mechanisms are both region and endpoint specific and invoke many surprising systems such as prostaglandins, endocannabinoids, and cell death proteins. Epigenetic modifications to the genome both establish and maintain sex differences in the brain and behavior. By understanding when, why, and how sex differences in the brain are established, we may also learn the source of strong gender biases in the relative risk and severity of numerous neurological diseases and disorders of mental health. Boys are much more likely to be diagnosed with autism spectrum or attention and hyperactivity disorders, as well as speech and language deficits, compared to girls. By contrast, women are more likely to suffer from affective disorders, such as depression, anxiety, compulsion, and eating disorders and more likely to experience autoimmune and neurodegenerative disorders. Schizophrenia with an early onset is more common in males but a late-onset version is markedly more frequent in females. Male biased disorders have origins in development while female biased disorders are almost exclusively post-puberty. This remarkable shift in disease risk demands our attention. Novel insights into the biological origins of disease are also gained by comparing and contrasting the same processes in different sexes.



Sex Differences In Neurology And Psychiatry


Sex Differences In Neurology And Psychiatry
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Author :
language : en
Publisher: Elsevier
Release Date : 2020-09-30

Sex Differences In Neurology And Psychiatry written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-30 with Medical categories.


Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. Explores sex differences in human neuroanatomy and neurophysiology Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context



Sex Differences And Implications For Translational Neuroscience Research


Sex Differences And Implications For Translational Neuroscience Research
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2011-01-25

Sex Differences And Implications For Translational Neuroscience Research written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-25 with Medical categories.


Biological differences between the sexes influence not only individual health but also public health, biomedical research, and health care. The Institute of Medicine held a workshop March 8-9, 2010, to discuss sex differences and their implications for translational neuroscience research, which bridges the gap between scientific discovery and application.



Sex Differences In Brain Function And Dysfunction


Sex Differences In Brain Function And Dysfunction
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Author : Claire Gibson
language : en
Publisher: Springer Nature
Release Date : 2023-03-01

Sex Differences In Brain Function And Dysfunction written by Claire Gibson and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-01 with Medical categories.


Does sex matter when it comes to brain function? This volume attempts to answer this very important question which is of relevance to the disciplines of psychology, neuroscience, psychiatry and neurology. Understanding how brain function and resultant behaviors may differ between the sexes impacts upon our knowledge of the pathology and development of treatments for various neurological and psychiatric disorders, particularly those that show significant sex differences in either prevalence and/or manifestation of symptoms. This volume covers three main themes of research into sex differences in basic neurobiology, psychology, preclinical research and clinical research. It begins by exploring our understanding of sex and gender in relation to both animal and human behaviors and discusses the relevance, and importance, of considering sex and gender when conducting research into brain function and behaviors. The second theme focuses on how sex and gender influence mental health and considers the impact of our immune system and the changes that occur with ageing. Finally, the third aspect focuses on examples of neurological disorder which show sex differences in terms of their aetiology and/or symptomology and considers the relevance in the development of treatment for these disorders including dementia, stroke and multiple sclerosis. This volume is of considerable interest to mental health and neurology professionals, including psychiatrists, neurologists, nurses, allied health clinicians and pharmacists. It is also helpful and important for preclinical researchers working in neuroscience, psychopharmacology and reproductive endocrinology.



Sex Differences In The Brain


Sex Differences In The Brain
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Author :
language : en
Publisher:
Release Date : 1984

Sex Differences In The Brain written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Brain categories.




Sex And The Brain


Sex And The Brain
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Author : Gillian Einstein
language : en
Publisher: MIT Press
Release Date : 2007-10-19

Sex And The Brain written by Gillian Einstein and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-19 with Medical categories.


A collection of foundational texts on the nature and behavioral consequences of sex differences in the brain, allowing readers to follow the development of a rapidly growing but contentious field and giving them the tools to analyze emerging scientific findings from many perspectives. This collection of foundational papers on sex differences in the brain traces the development of a much-invoked, fast-growing young field at the intersection of brain and behavior. The reader is introduced to the meaning and nature of sexual dimorphisms, the mechanisms and consequences of steroid hormone action, and the impact of the field on interpretations of sexuality and gender. Building on each other in point-counterpoint fashion, the papers tell a fascinating story of an emerging science working out its core assumptions. Experimental and theoretical papers, woven together by editor's introductions, open a window onto knowledge in the making and a vigorous debate between reductionist and pluralist interpreters. Five major sections include papers on conceptual and methodological background, central nervous system dimorphisms, mechanisms for creating dimorphisms, dimorphisms and cognition, and dimorphisms and identity. Each section builds from basic concepts to early experiments, from experimental models to humans, and from molecules to mind. Papers by such leading scholars as Arthur Arnold, Frank Beach, Anne Fausto-Sterling, Patricia Goldman-Rakic, Doreen Kimura, Simon LeVay, Bruce McEwen, Michael Merzenich, Bertram O'Malley, Geoffrey Raisman, and Dick Swaab, illustrate a rich blend of perspectives, approaches, methods, and findings. Sex and the Brain will show students how a scientific paper can be analyzed from many perspectives, and supply them with critical tools for judging a rapidly emerging science in a contentious area.



Bridging Gaps Between Sex And Gender In Neurosciences


Bridging Gaps Between Sex And Gender In Neurosciences
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Author : Annie Duchesne
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-14

Bridging Gaps Between Sex And Gender In Neurosciences written by Annie Duchesne and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-14 with categories.