Short Term Bioassays In The Analysis Of Complex Environmental Mixtures Iii
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Report Summaries
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Author : United States. Environmental Protection Agency
language : en
Publisher:
Release Date : 1983
Report Summaries written by United States. Environmental Protection Agency and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with categories.
Short Term Bioassays In The Analysis Of Complex Environmental Mixtures Iii
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Author : Michael D Waters
language : en
Publisher:
Release Date : 1983-03-01
Short Term Bioassays In The Analysis Of Complex Environmental Mixtures Iii written by Michael D Waters and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-03-01 with categories.
Short Term Bioassays In The Analysis Of Complex Environmental Mixtures Iii
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Author : Michael D. Waters
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Short Term Bioassays In The Analysis Of Complex Environmental Mixtures Iii written by Michael D. Waters and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
In the four years since the 1978 Symposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures the use of short-term bioassays to evaluate potential health hazards of complex environmental mixtures has substantially increased. Increased research activity has been particularly noticeable in mobile source emissions, where initial observations on the mutagenic activity of diesel particulate extracts reported at the 1978 symposium stimulated the development of major research programs in government and industry. In the absence of appropriate reference materials, the U.S. Environmental Protection Agency initiated comparative genotoxicity studies to determine the relative mutagenic and carcinogenic activity and, ultimately, the potential human health risk due to exposure to various complex emission products. Among the materials investigated were those of known health risk, such as coke oven and roofing tar emissions and cigarette smoke condensates, and those of unknown hazard, such as exhaust from diesel-and gasoline-powered vehicles. Studies on diesel emission products proved useful in short term bioassay development, as the diesel exhaust extracts were genetically active with low cellular toxicity and could be obtained in relatively large quantities. Availability of such samples aided chemical characterization, and it was eventually determined that the nitro-polynuclear aromatic hydrocarbons were among the mutagenic components of diesel exhaust particulate.
Short Term Bioassays In The Analysis Of Complex Environmental Mixtures Iv
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Author : Michael Waters
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Short Term Bioassays In The Analysis Of Complex Environmental Mixtures Iv written by Michael Waters and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
With this proceedings of the fourth symposium on complex mixtures, we continue to revise and extend our knowledge of genetic methods for the evaluation of chemical mixtures in the environment. The early chapters of this volume are devoted to new bioassay techniques that are directly applicable to the monitoring of environments contaminated with genotoxic chemicals. Microbiological methods have been further refined to meet the special needs of atmospheric monitoring so that very small samples may now be efficiently tested. New in situ methods utilizing green plants actually avoid many of the usual difficulties of sample collection and preparation and offer special advantages in monitoring wastewater, sludges, and hazardous wastes. Insects also are being employed very effectively in the evaluation of gaseous air pollutants in controlled laboratory investigations. Increased emphasis has been placed on a comprehensive assessment of the potential of complex mixtures t9 cause various kinds of genetic damage. New assays for chromosome structural and numerical aberrations in mammalian cells in vitro have been developed and are being applied in laboratory studies. Efforts to link tests for gene mutation and cell transformation in vitro with assays for tumorigenesis in vivo are contributing to the validation of the short-term testing approach. Studies comparing in vitro and in vivo data on a coal conversion by-product, on polycyclic aromatic hydrocarbons, and on mineral fibers are reported in separate papers. Later chapters are devoted to investigations on the fractionation and biological evaluation of specific chemical components within complex mixtures.
Methods For Genetic Risk Assessment
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Author : David Brusick
language : en
Publisher: CRC Press
Release Date : 2024-11-01
Methods For Genetic Risk Assessment written by David Brusick and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-01 with Science categories.
Genetic disease contributes to a major portion of our health care costs. While most of the human genetic burden is transmitted from generation to generation, environmental chemicals capable of reacting with germ cell DNA could produce new mutations, resulting in an even greater genetic liability for the next generation. The potential impact of environmental mutagens on the health and viability of other living things is important to consider as well. Methods for Genetic Risk Assessment features contributions from international experts to provide a comprehensive review of the current status of genetic risk assessment. You'll learn about various methods and strategies for when and how to conduct genetic risk assessments on human populations. You will also learn about the potential effects of environmental genotoxins on nonhuman organisms.
Mobile Source Emissions Including Policyclic Organic Species
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Author : D. Rondia
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mobile Source Emissions Including Policyclic Organic Species written by D. Rondia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book contains the combined papers from a NATO sponsored meeting entitled "Mobile Source Emissions Including Polycyclic Organic Species". This meeting was held in Liege, Belgium, from August 30 to September 2, 1982, as an Advanced Research Workshop (ARW). Specialists from 13 countries met to discuss the impacts of fuel type and engine operation on emissions from gasoline and diesel-powered vehicles. The meeting was organized into five sessions: basic studies, biological activity, analytical methods, data bases, engineering and international research programs. The five sessions were each followed by intensive discussions on the important conclusions to be drawn from the data presented. From these session discussions, subcommittee efforts and a final group discussion on all the research results presented, a meeting summary was prepared by the editors that presents the major findings of the conference and gives detailed recommendations for future research. This summary is included at the end of the book. The summary i"nc1udes highlights of data presented, areas of research needs, recommendations for standardization of test parameters and species analyzed, suggested new methodology for characterizing mobile emissions, trends in fuel use including diesel, gasoline, anti-knock additives and blending agents, operation of catalysts, control strategies, implications from both in vivo and in vitro health effects studies, and a presenta tion of the scopeiand direction of several large international programs that are major studies of mobile source performance.
Alternative Ecological Risk Assessment
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Author : Lawrence V. Tannenbaum
language : en
Publisher: John Wiley & Sons
Release Date : 2013-09-10
Alternative Ecological Risk Assessment written by Lawrence V. Tannenbaum and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-10 with Science categories.
In Alternative Ecological Risk Assessment the author, Lawrence V. Tannenbaum, provides a critical review of current practices in the ecological risk assessment field and proposes alternatives that are supported by established science and keen observation. It is hoped that this approach will pave the way to a greater understanding of what appropriate and useful ecological assessment for contaminated sites should entail. He demonstrates that in most cases current practices do not provide for an assessment of ecological risk, and moreover, that endeavoring to assess ecological risk is actually an unnecessary undertaking at conventional hazardous waste sites. (He states, for example, that the concept of scale is often ignored by practitioners, questions why animals like deer are routinely assessed at 5-acre sites, and challenges the ecotoxicology data currently used.) The book is aimed at students and professionals in the fields of environmental science, ecology, ecotoxicology, and health risk assessment.
Toxicology Of Amphibian Tadpoles
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Author : Eduardo Alves de Almeida
language : en
Publisher: CRC Press
Release Date : 2023-12-15
Toxicology Of Amphibian Tadpoles written by Eduardo Alves de Almeida and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-15 with Medical categories.
Anuran amphibians are among the animal groups with the highest rate of population decline on the planet. Among the factors driving this decline are environmental pollutants, whose negative effects on larvae and tadpoles are still relatively little studied. This is the first book devoted entirely to studying the effects of environmental pollutants on amphibian tadpoles. Throughout its 14 chapters, various aspects of the toxic effects of different classes of environmental contaminants are explored, such as the toxicokinetics of toxic compounds in tadpoles and their health effects, which may result in negative consequences at populations level.
Environmental Health Perspectives
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Author :
language : en
Publisher:
Release Date : 1993
Environmental Health Perspectives written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Environmental health categories.
Handbook Of Ecotoxicology
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Author : David J. Hoffman
language : en
Publisher: CRC Press
Release Date : 2002-11-13
Handbook Of Ecotoxicology written by David J. Hoffman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-11-13 with Science categories.
Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. Focusing on toxic substance and how they affect the ecosystems worldwide, the book presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. This is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.