Signalling Pathways In Embryonic Development

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Signalling Pathways In Embryonic Development

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Author : Juan J. Sanz-Ezquerro
language : en
Publisher: Frontiers Media SA
Release Date : 2017-11-30

Signalling Pathways In Embryonic Development written by Juan J. Sanz-Ezquerro and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-30 with categories.

The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate, differentiate and form tissues at the correct place and time. These processes are genetically controlled and depend both on the history of cells, their lineage, and on the activities of signalling pathways, which coordinate the cell interactions leading to organogenesis. The aim of the Frontiers research topic “Signalling pathways in embryonic development” has been to provide a forum for experts in cell and developmental biology to share recent advances in the field of signalling during embryonic development. Sixteen articles in a variety of formats are united in this Topic, offering a valuable collection for researchers looking for an update in the knowledge of signalling pathways operating during embryogenesis. The works, focused mainly on vertebrates, explore different aspects of this theme from cell communication to organ formation and have implications for areas as distant as evolution or pathology. Understanding developmental signalling pathways is important for several reasons. It gives us information about basic mechanisms of cell function and interactions needed for morphogenesis and organogenesis. It uncovers the basis of congenital malformations, since errors at any step of cell signalling during development are a major cause of defects. This fundamental insight gives us clues to understand the mechanisms operating in evolution that explain diversity in form and function. And finally, it allows the identification of possible causes of disease in the adult organism (such as cancer or degenerative diseases) pinpointing possible targets for therapeutic approaches.

Molecular Biology Of The Cell

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Author :
language : en
Publisher:
Release Date : 2004

Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.

Animal Developmental Biology

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Author : Julia Paxson
language : en
Publisher: Oxford University Press
Release Date : 2024

Animal Developmental Biology written by Julia Paxson and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with Science categories.

Written primarily for 16-19-year-old students, this primer introduces the subject of developmental biology through a wide range of organisms, offering insights into the fundamental principles that shape life's diverse and extraordinary forms. It covers all the essential topics, including cell biology, cell signalling, cell specialization, genomic control of development, evidence for evolution, and cell ageing and death.The author guides students carefully and gradually through the concise contents, providing a robust basis for understanding the molecular and morphological events that occur during embryo development, but that are also important in adult homeostasis, regeneration, and disease. Students will delve into the secrets of stem cells, the marvels of regeneration, and the paradox of how a broadly conserved genome can support the biodiversity we see throughout the natural world. Engaging case studies and 'scientific approach' boxes challenge the reader to think critically and practice scientific inquiry, while open-ended discussion questions draw on students' creativity and curiosity.Animal Developmental Biology is the ideal companion for students transitioning from biology at school to university. It offers a first taste of biology beyond the classroom and illustrates the relevance of concepts encountered at school to current research.Digital formats and resourcesThe book is available for students and institutions to purchase in a variety of formats, and is supported by online resources:· The e-book offers a mobile-compatible experience and convenient access along with functionality tools, navigation features, and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks http://www.oxfordtextbooks.co.uk/ebooks· Online resources, available for registered adopters, include downloadable figures and tables from the book.

Cell Signaling Pathways In Development

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Author :
language : en
Publisher: Academic Press
Release Date : 2022-05-20

Cell Signaling Pathways In Development written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-20 with Science categories.

Cell Signaling Pathways in Development, Volume 149 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Ephrin signaling, Cell signaling to the extracellular matrix, Signaling by TGF-b superfamily members, Hedgehog signaling, Parallels in signaling during development and regeneration, Hippo signaling, Wnt/PCP signaling, Signaling oscillations in presomitic mesoderm, FGFs/RTKs subcellular signaling compartments, and Signaling dynamics. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Includes the latest information on Cell Signaling Pathways in Development

Veterinary Embryology

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Author : T. A. McGeady
language : en
Publisher: John Wiley & Sons
Release Date : 2017-02-02

Veterinary Embryology written by T. A. McGeady and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-02 with Medical categories.

Veterinary Embryology, 2nd Edition, has been updated to reflect the many changes that have developed in the field; the text has been fully revised and expanded and is now in full colour and many pedagogical features and a companion website have been developed. A new edition of this highly successful student textbook, updated to reflect the latest developments in the field of embryology, with the inclusion of four new chapters Written by a team of authors with extensive experience of teaching this subject Short concise chapters on key topics describe complex concepts in a user-friendly way Additional tables, flow diagrams and numerous hand-drawn illustrations support the concepts presented in the text

Cell Signaling During Mammalian Early Embryo Development

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Author : Henry J. Leese
language : en
Publisher: Springer
Release Date : 2015-05-08

Cell Signaling During Mammalian Early Embryo Development written by Henry J. Leese and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-08 with Science categories.

The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at this critical stage of the life cycle -- is seriously incomplete. This volume is the first to address this issue by describing the current state of knowledge on cell signaling during mammalian early embryo development and highlighting priority areas for research.

Signaling Pathways In Liver Diseases

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Author : Jean-Francois Dufour
language : en
Publisher: John Wiley & Sons
Release Date : 2015-11-09

Signaling Pathways In Liver Diseases written by Jean-Francois Dufour and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-09 with Medical categories.

Signaling Pathways in Liver Diseases, Third Edition again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signaling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however, the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format. With increased focus on the comprehension of cellular mechanisms involved in steatohepatitis, cirrhosis, and liver tumors, which has led to changes in the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as: Autophagy Notch Pathway P13K/PTEN Signaling in Liver Diseases Sirtuins Hepcidin and Iron Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis Oxidative Stress and Signaling in the Liver. Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom has provided clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge. Signaling Pathways in Liver Disease, Third Edition is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.

Targeting Developmental Pathways In Inflammation And Disease

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Author : Maria Pia Felli
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-05

Targeting Developmental Pathways In Inflammation And Disease written by Maria Pia Felli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-05 with Science categories.

Wnt Signaling In Embryonic Development

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Author : Sergei Y. Sokol
language : en
Publisher: Elsevier
Release Date : 2011-09-22

Wnt Signaling In Embryonic Development written by Sergei Y. Sokol and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-22 with Science categories.

A superb compilation of reviews from leading experts in the field of Wnt signaling (signaling molecules that regulate cell-to-cell interactions during embryogenesis), volume 17 in the Advances in Developmental Biology series offers 7 chapters, each devoted to a separate area of research on Wnt signaling. Written by specialists in the field, these chapters cover different levels of signaling, including: ligands, receptors, cytoplasmic and nuclear components of the pathway. This book discusses a number of model systems including mice, Drosophila, Xenopus, zebrafish, C. elegans, and mammalian cells. Together, these chapters review the available knowledge and will fill gaps in our understanding of this interesting network of cell signaling processes.* Includes two parts devoted to the canonical (beta-catenin dependent) and non-canonical branches of Wnt signalling to the cytoskeleton* Offers insight to large genomic data that are now available for the analysis of Wnt gene targets* Discusses regulators of the cytoskeleton such as small GTPAses of the Rho family, jun-N-terminal kinases and other MAP kinases, and proteins involved in the generation of cell polarity

Stem Cells And Signaling Pathways

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Author : Surajit Pathak
language : en
Publisher: Elsevier
Release Date : 2023-09-28

Stem Cells And Signaling Pathways written by Surajit Pathak and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-28 with Science categories.

Stem Cells and Signaling Pathways provides mechanistic insights into the role of stem cells to combat the COVID-19 outbreak and other pathologies where a cytokine storm is the cause of concern for e.g., radiation exposure, multiple organ failure and sepsis. The advent of SARS-CoV-2 resulted in a global pandemic, putting individuals with other comorbidities at a higher risk of infection. The whole world witnessed a massive shortage of medical and other essential supplies needed to combat the virus. That said, stem cell therapy has emerged as a potential treatment for viral diseases, including but not limited to COVID-19. Interestingly, the clinical trials in the patients having COVID-19 complications depicted faster recovery in patients post mesenchymal stem cells therapy owing to the decreased cytokines levels, anti-viral effects and regeneration of the infected tissue. - Provides a compilation of chapters dedicated to the study of the field with respect to properties of stem cells and their signaling pathways. It also provides detailed information on signaling pathways associated with stem cells - Provides a detailed and updated view of stem cell biology - Covers a wide range of areas within basic and translational research appropriate for scientists and clinicians engaged in studying the treatments for diseases from interdisciplinary perspectives - Highlights the use of different models for stem cell research, significance of stem cell signaling in drug discovery