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Single Neuron Studies Of The Human Brain

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Single Neuron Studies Of The Human Brain

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Author : Itzhak Fried
language : en
Publisher: MIT Press
Release Date : 2014-06-13

Single Neuron Studies Of The Human Brain written by Itzhak Fried and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-13 with Science categories.

Foundational studies of the activities of spiking neurons in the awake and behaving human brain and the insights they yield into cognitive and clinical phenomena. In the last decade, the synergistic interaction of neurosurgeons, engineers, and neuroscientists, combined with new technologies, has enabled scientists to study the awake, behaving human brain directly. These developments allow cognitive processes to be characterized at unprecedented resolution: single neuron activity. Direct observation of the human brain has already led to major insights into such aspects of brain function as perception, language, sleep, learning, memory, action, imagery, volition, and consciousness. In this volume, experts document the successes, challenges, and opportunity in an emerging field. The book presents methodological tutorials, with chapters on such topics as the surgical implantation of electrodes and data analysis techniques; describes novel insights into cognitive functions including memory, decision making, and visual imagery; and discusses insights into diseases such as epilepsy and movement disorders gained from examining single neuron activity. Finally, contributors consider future challenges, questions that are ripe for investigation, and exciting avenues for translational efforts. Contributors Ralph Adolphs, William S. Anderson, Arjun K. Bansal, Eric J. Behnke, Moran Cerf, Jonathan O. Dostrovsky, Emad N. Eskandar, Tony A. Fields, Itzhak Fried, Hagar Gelbard-Sagiv, C. Rory Goodwin, Clement Hamani, Chris Heller, Mojgan Hodaie, Matthew Howard III, William D. Hutchison, Matias Ison, Hiroto Kawasaki, Christof Koch, Rüdiger Köhling, Gabriel Kreiman, Michel Le Van Quyen, Frederick A. Lenz, Andres M. Lozano, Adam N. Mamelak, Clarissa Martinez-Rubio, Florian Mormann, Yuval Nir, George Ojemann, Shaun R. Patel, Sanjay Patra, Linda Philpott, Rodrigo Quian Quiroga, Ian Ross, Ueli Rutishauser, Andreas Schulze-Bonhage, Erin M. Schuman, Demetrio Sierra-Mercado, Richard J. Staba, Nanthia Suthana, William Sutherling, Travis S. Tierney, Giulio Tononi, Oana Tudusciuc, Charles L. Wilson

Single Neuron Studies Of The Human Brain

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Author : Itzhak Fried
language : en
Publisher: MIT Press
Release Date : 2014-05-30

Discovering The Brain

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Author : National Academy of Sciences
language : en
Publisher: National Academies Press
Release Date : 1992-01-01

Discovering The Brain written by National Academy of Sciences and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-01-01 with Medical categories.

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Human Spatial Navigation

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Author : Arne Ekstrom
language : en
Publisher: Princeton University Press
Release Date : 2018-08-07

Human Spatial Navigation written by Arne Ekstrom and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-07 with Psychology categories.

The first book to comprehensively explore the cognitive foundations of human spatial navigation Humans possess a range of navigation and orientation abilities, from the ordinary to the extraordinary. All of us must move from one location to the next, following habitual routes and avoiding getting lost. While there is more to learn about how the brain underlies our ability to navigate, neuroscience and psychology have begun to converge on some important answers. In Human Spatial Navigation, four leading experts tackle fundamental and unique issues to produce the first book-length investigation into this subject. Opening with the vivid story of Puluwat sailors who navigate in the open ocean with no mechanical aids, the authors begin by dissecting the behavioral basis of human spatial navigation. They then focus on its neural basis, describing neural recordings, brain imaging experiments, and patient studies. Recent advances give unprecedented insights into what is known about the cognitive map and the neural systems that facilitate navigation. The authors discuss how aging and diseases can impede navigation, and they introduce cutting-edge network models that show how the brain can act as a highly integrated system underlying spatial navigation. Throughout, the authors touch on fascinating examples of able navigators, from the Inuit of northern Canada to London taxi drivers, and they provide a critical lens into previous navigation research, which has primarily focused on other species, such as rodents. An ideal book for students and researchers seeking an accessible introduction to this important topic, Human Spatial Navigation offers a rich look into spatial memory and the neuroscientific foundations for how we make our way in the world.

From Neurons To Neighborhoods

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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2000-11-13

From Neurons To Neighborhoods written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-11-13 with Social Science categories.

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Biophysics Of Computation

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Author : Christof Koch
language : en
Publisher: Oxford University Press
Release Date : 2004-10-28

Biophysics Of Computation written by Christof Koch and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-28 with Medical categories.

Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.

Biometrics And Neuroscience Research In Business And Management

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Author : Luiz Moutinho
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2024-06-17

Biometrics And Neuroscience Research In Business And Management written by Luiz Moutinho and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-17 with Business & Economics categories.

This book is designed to impart and convey knowledge as well as understanding of the range of biometric technologies and cybertechnologies, while also stressing their advantages and disadvantages. The authors develop an appreciation for and breadth of knowledge that spans the full range of neuroscience sub-disciplines, including behavioural, cognitive, and computational neuroscience. Furthermore, the content of the book is geared to be able to place neuroscience into an ethical context, especially showing how studying the brain and behaviour can contribute to the resolution of ethical, social, and environmental issues.

Memory Amnesia And The Hippocampal System

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Author : Neal J. Cohen
language : en
Publisher: MIT Press
Release Date : 1993

Memory Amnesia And The Hippocampal System written by Neal J. Cohen and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.

In this sweeping synthesis, Neal J. Cohen and Howard Eichenbaum bring together converging findings from neuropsychology, neuroscience, and cognitive science that provide the critical clues and constraints for developing a more comprehensive understanding of memory. Specifically, they offer a cognitive neuroscience theory of memory that accounts for the nature of memory impairment exhibited in human amnesia and animal models of amnesia, that specifies the functional role played by the hippocampal system in memory, and that provides further understanding of the componential structure of memory.The authors' central thesis is that the hippocampal system mediates a capacity for declarative memory, the kind of memory that in humans supports conscious recollection and the explicit and flexible expression of memories. They argue that this capacity emerges from a representation of critical relations among items in memory, and that such a relational representation supports the ability to make inferences and generalizations from memory, and to manipulate and flexibly express memory in countless ways. In articulating such a description of the fundamental nature of declarative representation and of the mnemonic capabilities to which it gives rise, the authors' theory constitutes a major extension and elaboration of the earlier procedural-declarative account of memory.Support for this view is taken from a variety of experimental studies of amnesia in humans, nonhuman primates, and rodents. Additional support is drawn from observations concerning the neuroanatomy and neurophysiology of the hippocampal system. The data taken from divergent literatures are shown to converge on the central theme of hippocampal involvement in declarative memory across species and across behavioral paradigms.

Mirroring People

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Author : Marco Iacoboni
language : en
Publisher: Macmillan + ORM
Release Date : 2009-06-23

Mirroring People written by Marco Iacoboni and has been published by Macmillan + ORM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-23 with Psychology categories.

What accounts for the remarkable ability to get inside another person's head—to know what they're thinking and feeling? "Mind reading" is the very heart of what it means to be human, creating a bridge between self and others that is fundamental to the development of culture and society. But until recently, scientists didn't understand what in the brain makes it possible. This has all changed in the last decade. Marco Iacoboni, a leading neuroscientist whose work has been covered in The New York Times, the Los Angeles Times, and The Wall Street Journal, explains the groundbreaking research into mirror neurons, the "smart cells" in our brain that allow us to understand others. From imitation to morality, from learning to addiction, from political affiliations to consumer choices, mirror neurons seem to have properties that are relevant to all these aspects of social cognition. As The New York Times reports: "The discovery is shaking up numerous scientific disciplines, shifting the understanding of culture, empathy, philosophy, language, imitation, autism and psychotherapy." Mirroring People is the first book for the general reader on this revolutionary new science.

The Oxford Companion To Consciousness

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Author : Tim Bayne
language : en
Publisher: Oxford University Press
Release Date : 2009

The Oxford Companion To Consciousness written by Tim Bayne and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Philosophy categories.

Consciousness is undoubtedly one of the last remaining scientific mysteries and hence one of the greatest contemporary scientific challenges. How does the brain's activity result in the rich phenomenology that characterizes our waking life? Are animals conscious? Why did consciousness evolve? How does science proceed to answer such questions? Can we define what consciousness is? Can we measure it? Can we use experimental results to further our understanding of disorders of consciousness, such as those seen in schizophrenia, delirium, or altered states of consciousness? These questions are at the heart of contemporary research in the domain. Answering them requires a fundamentally interdisciplinary approach that engages not only philosophers, but also neuroscientists and psychologists in a joint effort to develop novel approaches that reflect both the stunning recent advances in imaging methods as well as the continuing refinement of our concepts of consciousness. In this light, the Oxford Companion to Consciousness is the most complete authoritative survey of contemporary research on consciousness. Five years in the making and including over 250 concise entries written by leaders in the field, the volume covers both fundamental knowledge as well as more recent advances in this rapidly changing domain. Structured as an easy-to-use dictionary and extensively cross-referenced, the Companion offers contributions from philosophy of mind to neuroscience, from experimental psychology to clinical findings, so reflecting the profoundly interdisciplinary nature of the domain. Particular care has been taken to ensure that each of the entries is accessible to the general reader and that the overall volume represents a comprehensive snapshot of the contemporary study of consciousness. The result is a unique compendium that will prove indispensable to anyone interested in consciousness, from beginning students wishing to clarify a concept to professional consciousness researchers looking for the best characterization of a particular phenomenon.

Single Neuron Studies Of The Human Brain

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