Skeletal Impact Of Disease


Skeletal Impact Of Disease
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Skeletal Impact Of Disease


Skeletal Impact Of Disease
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Author : Bruce M. Rothschild
language : en
Publisher: New Mexico Museum of Natural History and Science
Release Date : 2006

Skeletal Impact Of Disease written by Bruce M. Rothschild and has been published by New Mexico Museum of Natural History and Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Bones categories.




Modern Paleopathology The Study Of Diagnostic Approach To Ancient Diseases Their Pathology And Epidemiology


Modern Paleopathology The Study Of Diagnostic Approach To Ancient Diseases Their Pathology And Epidemiology
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Author : Bruce M. Rothschild
language : en
Publisher: Springer Nature
Release Date : 2023-09-27

Modern Paleopathology The Study Of Diagnostic Approach To Ancient Diseases Their Pathology And Epidemiology written by Bruce M. Rothschild and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-27 with Science categories.


The study of paleopathology has two very different constituencies, the medical scientist and the zoologist/paleontologist/anthropologist. Their investigative procedures and professional jargon are different, sometimes to the point of mutual incomprehensibility. Paleontologists/anthropologists/zoologists have a limited data base for the characterization and interpretation of pathology. This must come from the human and veterinary medical experience. What, beyond intellectual satisfaction, can the health care community expect from this relationship? The past history of the appearance and dispersal of infectious disease and cancer is of considerable theoretical importance and leads to new insights on the nature and transmission of diseases that are otherwise ambiguous. The discovery of rheumatoid arthritis in pre-Columbian North America exemplifies insights gained. The current effort delineates osseous impact of disease (as manifest in clinical populations diagnosed in life), representation in the zoologic, paleontologic and anthropologic record, and assessment techniques that can be confidently applied. The chapters form “columns” that provide the foundation for scientific critical thinking. The actual integration of the information is in its application. Our purpose is to provide a data base and atlas of actually documented skeletal impact of diseases (as population phenomenon), an initial data base of reported skeletal pathology, and a methodology for expanding this to new arenas. The first section of the book examines the scientific basis of paleopathology, its transition from speculation-based musings, resolution of misconceptions and the denouement of paleo-epidemiology. The second section provides holistic analysis of the gamut of pathology/diseases with significant skeletal impact, with a validated archeologic/zoological/paleontological record. The third section provides a glossary to resolve the semantic challenges inherent to interdisciplinary efforts. The fourth section provides an atlas of pathology representation in the fossil record. Ultimately, this book intends to present a scientifically-validated approach to recognition of disease in the archeological, zoological and paleontological record, superseding previous speculation-based offerings.



Musculo Skeletal Disorders


Musculo Skeletal Disorders
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Author : Jennifer L. Kelsey
language : en
Publisher:
Release Date : 1978

Musculo Skeletal Disorders written by Jennifer L. Kelsey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Musculoskeletal system categories.




Diabetic Bone Disease


Diabetic Bone Disease
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Author : Beata Lecka-Czernik
language : en
Publisher: Springer
Release Date : 2015-10-12

Diabetic Bone Disease written by Beata Lecka-Czernik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-12 with Medical categories.


Providing the most up-to-date research and current clinical knowledge of diabetic bone disease and the challenges still facing the research and clinical care communities, this book unites insights from endocrinology and orthopedics to create a truly unique text. The first part covers clinical and pre-clinical applications and research. The first two chapters present the clinical and epidemiological data about diabetic bone disease, evaluated and reviewed for type 1 and type 2, respectively. This is followed by discussions of how the propensity to fracture in diabetic bone disease can impact fracture risk assessments and how it can be adjusted for using current clinically relevant fracture risk models. A comprehensive overview of orthopedic complications observed in diabetes is next, as well as a focus on the consequences of diabetes on periodontal disease. Other topics include the utility of skeletal biomarkers in assessing diabetic bone disease, how drugs used to treat diabetes may also have skeletal consequences, and the possibility that diabetes may fundamentally impact early progenitor cells of various bone lineages and thus globally impact bone. The second part covers biomechanics and bone quality in diabetes: how diabetes ultimately may impact the architecture, integrity, and quality of bone. Utilizing the expertise of top researcher and clinicians in diabetic bone disease in one comprehensive text, this volume will be a useful and thought-provoking resource for endocrinologists and orthopedic surgeons alike.



Diabetes Mellitus


Diabetes Mellitus
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Author : Meng Hee Tan
language : en
Publisher: Academic Press
Release Date : 2020-07-28

Diabetes Mellitus written by Meng Hee Tan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-28 with Medical categories.


Diabetes Mellitus: Impact on Bone, Dental and Musculoskeletal Health focuses on the under recognized and managed conditions associated with diabetes, including impacts on bone health, dental health, hand, and foot disorders, wounds, infections, and musculoskeletal disorders. A full understanding of the relationship of diabetes to skeletal disorders remains elusive and many physicians who deal with such issues are unclear about causes and management. While the macro- and microvascular complications associated with diabetes mellitus are well known, complications associated with bone, dental and musculoskeletal health are not. Endocrinologists, primary care physicians, geriatricians, podiatrists, dentists, and researchers interested in diabetes mellitus associated bone, dental and musculoskeletal disorders will find this to be a comprehensive tome on the topic. Covers clinically important complications of diabetes that are less understood Presents up-to-date, thoroughly referenced information for both clinicians, researchers and other healthcare providers Highlights current research and treatment for skeletal deficits and complications due to diabetes types 1 and 2 Serves as a one-stop resource for the bone, dental and muscular disorders associated with diabetes mellitus



Identification Of Pathological Conditions In Human Skeletal Remains


Identification Of Pathological Conditions In Human Skeletal Remains
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Author : Donald J. Ortner
language : en
Publisher: Academic Press
Release Date : 2003-01-06

Identification Of Pathological Conditions In Human Skeletal Remains written by Donald J. Ortner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-06 with Language Arts & Disciplines categories.


Identicication of Pathological Conditions in Human Skeletal Remains provides an integrated and comprehensive overview of pathological conditions that affect the human skeleton. The primary objective is to assist those who conduct research on archeological skeletal remains in interpreting abnormal conditions that they might encounter in the course of their research. However, there is much that ancient skeletal remains can reveal to the modern orthopedist, pathologist, forensic anthropologist, and radiologist about the skeletal manifestations of diseases that are rarely encountered in modern medical practice. The medical historian will find information on the antiquity and early geographical distribution of many diseases. All of the major categories of disease that affect bone are reviewed on the basis of the literature on the radiology and pathology of these diseases. This review is followed by a discussion of the literature on the paleopathological cases thought to represent each of the morbid categories affecting bone. This book is based on extensive individual and collaborative research by the author and contributing authors on the known parameters of basic calcified tissue biology and modern skeletal diseases and their expression in antiquity. The monograph provides essential text and illustrative materials on bone pathology, which will improve the diagnostic ability of those interested in human dry bone pathology. It also provides time depth to our understanding of the effect of disease on past human populations. Key Features * Comprehensive review of skeletal diseases encountered in archeological human remains * More than 1100 photographs and line drawings illustrating skeletal diseases including both microscopic and gross features * Based on extensive research on skeletal paleopathology in many countries for over 35 years * Review of important theoretical issues in interpreting evidence of skeletal disease in archeological human populations



Genetics Of Bone Biology And Skeletal Disease


Genetics Of Bone Biology And Skeletal Disease
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Author : Rajesh V. Thakker
language : en
Publisher: Academic Press
Release Date : 2017-10-31

Genetics Of Bone Biology And Skeletal Disease written by Rajesh V. Thakker and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-31 with Medical categories.


Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder



Bone Diseases Translational Research And Clinical Applications


Bone Diseases Translational Research And Clinical Applications
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Author : Dan Heller
language : en
Publisher: States Academic Press
Release Date : 2023-09-26

Bone Diseases Translational Research And Clinical Applications written by Dan Heller and has been published by States Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-26 with Health & Fitness categories.


Bone diseases refer to a group of diseases or injuries that affect human bones, which lead to abnormalities of the human skeletal system. Abnormal stress on bone, metabolic bone diseases, deficient blood supply to bone, bone tumor, infectious diseases of bone and fractures are a few major types of bone diseases. Lack of physical activity has a profound impact on the bone tissue because of lower level of mechanical stimulus that aids in bone formation. Metabolic bone diseases are a result of inadequate supply of amino acids for the production of collagen, calcium and phosphate. There are several therapeutic and corrective measures to treat bone diseases. One such measure is anthroplasty that helps in restoration of normal joint motion in rheumatoid arthritis of the elbow or hip. Bone transplantation targets stimulation of bone formation that provides structural support until a defect gets bridged by new bone. This book includes contributions of experts and scientists which will provide innovative insights on the translational research and its clinical applications in the treatment of bone diseases. Coherent flow of topics, student-friendly language, and extensive use of examples make this book an invaluable source of knowledge.



Osteoporosis In Men


Osteoporosis In Men
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Author : Eric S. Orwoll
language : en
Publisher: Academic Press
Release Date : 2009-11-30

Osteoporosis In Men written by Eric S. Orwoll and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-30 with Medical categories.


Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. Brings together more eminent investigators and clinicians to interpret developments in this growing field Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy There is no book on the market that covers osteoporosis in men as comprehensively as this book



New Insights Into Estrogen Estrogen Receptor Effects In The Cardiac And Skeletal Muscle


New Insights Into Estrogen Estrogen Receptor Effects In The Cardiac And Skeletal Muscle
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Author : Georgios Kararigas
language : en
Publisher: Frontiers Media SA
Release Date : 2020-05-06

New Insights Into Estrogen Estrogen Receptor Effects In The Cardiac And Skeletal Muscle written by Georgios Kararigas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-06 with categories.