Skin Permeation And Disposition Of Therapeutic And Cosmeceutical Compounds


Skin Permeation And Disposition Of Therapeutic And Cosmeceutical Compounds
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Skin Permeation And Disposition Of Therapeutic And Cosmeceutical Compounds


Skin Permeation And Disposition Of Therapeutic And Cosmeceutical Compounds
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Author : Kenji Sugibayashi
language : en
Publisher: Springer
Release Date : 2017-11-28

Skin Permeation And Disposition Of Therapeutic And Cosmeceutical Compounds written by Kenji Sugibayashi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-28 with Medical categories.


This book reviews skin permeation and disposition of chemical compounds. Skin is utilized as an administration site for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Their usefulness is closely related to the permeation and disposition of entrapped active ingredients through and into the skin. Skin permeation, disposition, and metabolism of chemicals are first summarized in the general introduction. Then primary topical formulations are explained in the second part, “Basic Formulations Applied to Skin”. The explanation for the active compounds and formulations are of the most important parts required to fabricate these formulations. Skin absorption of chemicals is generally much lower than oral and the other mucosal absorptions, so that skin-penetration enhancement is a key issue to have good formulations topically applied. Part 3 presents “Skin Penetration Enhancement”. In addition, Part 4, “Selection of Topically Applied Chemical Candidates”, deals with selection methods of topically applied ingredients for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Parts 5 and 6, “Safety Assessment of Topically Applied Compounds“ and “Experimental Methods of Skin Permeation“, respectively, show safety issues and experimental methods for topical formulations. The final part consists of comments on therapeutic and cosmetic formulations by medical doctors and pharmacists. Their comments are especially helpful for pharmaceutical and cosmetic researchers who study dermatopharmacokinetics and topical formulations. This volume is particularly useful for those working in R&D, graduate students, and educators in the area of pharmaceutics, cosmetic sciences, dermatological sciences, pharmacology, toxicology, biopharmacy, pharmacokinetics, physical pharmacy, chemical engineering, and related fields.



Skin Permeation


Skin Permeation
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Author : Joel L. Zatz
language : en
Publisher:
Release Date : 1993

Skin Permeation written by Joel L. Zatz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Skin categories.




Basic Fundamentals Of Drug Delivery


Basic Fundamentals Of Drug Delivery
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Author :
language : en
Publisher: Academic Press
Release Date : 2018-11-30

Basic Fundamentals Of Drug Delivery written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-30 with Business & Economics categories.


Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation. Provides up-to-date information on translating the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as orally, parenterally, transdermally or through inhalation Contains extensive references and further reading for course and self-study



Bioactive Loaded Nanomedicine For The Management Of Health And Disease


Bioactive Loaded Nanomedicine For The Management Of Health And Disease
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Author : Mahfoozur Rahman
language : en
Publisher: CRC Press
Release Date : 2022-12-23

Bioactive Loaded Nanomedicine For The Management Of Health And Disease written by Mahfoozur Rahman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-23 with Science categories.


The new book focuses on the use of natural active substances and nutraceuticals in nano-research for improved healthcare management and applications. It explores advanced nanomaterials that can be utilized for the encapsulation of nutrients, vitamins, and phytoconstituents for the treatment of cancer, psychotic and manic disorders, and chronic inflammation, such as arthritis and psoriasis, as well as for other healthcare issues, such as skin diseases and skin care, atherosclerosis, and more. The chapters discuss the remarkable advantages of using new bioactive and nutraceutical drugs, which offer improved solubility, bioavailability, simultaneous drug delivery, safety extension, long-term delivery, better dissemination of tissue macrophages, security against toxicity, increase in pharmacological activity, and enhanced physical and chemical protection.



Dermatologic Cosmeceutic And Cosmetic Development


Dermatologic Cosmeceutic And Cosmetic Development
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Author : Kenneth A. Walters
language : en
Publisher: CRC Press
Release Date : 2007-12-13

Dermatologic Cosmeceutic And Cosmetic Development written by Kenneth A. Walters and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-13 with Medical categories.


Recent advances in our understanding of the development and morphology of normal skin have led to improved methods to deliver therapeutic compounds to selected targeted areas both within the skin and systemically. This reference provides a clear overview of pharmaceutical and cosmetic practices, drugs, and therapies to manage and treat major and mi



Compounded Topical Pain Creams


Compounded Topical Pain Creams
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2020-07-21

Compounded Topical Pain Creams written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-21 with Medical categories.


Pain is both a symptom and a disease. It manifests in multiple forms and its treatment is complex. Physical, social, economic, and emotional consequences of pain can impair an individual's overall health, well-being, productivity, and relationships in myriad ways. The impact of pain at a population level is vast and, while estimates differ, the Centers for Disease Control and Prevention reported that 50 million U.S. adults are living in pain. In terms of pain's global impact, estimates suggest the problem affects approximately 1 in 5 adults across the world, with nearly 1 in 10 adults newly diagnosed with chronic pain each year. In recent years, the issues surrounding the complexity of pain management have contributed to increased demand for alternative strategies for treating pain. One such strategy is to expand use of topical pain medicationsâ€"medications applied to intact skin. This nonoral route of administration for pain medication has the potential benefit, in theory, of local activity and fewer systemic side effects. Compounding is an age-old pharmaceutical practice of combining, mixing, or adjusting ingredients to create a tailored medication to meet the needs of a patient. The aim of compounding, historically, has been to provide patients with access to therapeutic alternatives that are safe and effective, especially for people with clinical needs that cannot otherwise be met by commercially available FDA-approved drugs. Compounded Topical Pain Creams explores issues regarding the safety and effectiveness of the ingredients in these pain creams. This report analyzes the available scientific data relating to the ingredients used in compounded topical pain creams and offers recommendations regarding the treatment of patients.



Polymeric Gels


Polymeric Gels
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Author : Kunal Pal
language : en
Publisher: Woodhead Publishing
Release Date : 2018-06-15

Polymeric Gels written by Kunal Pal and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-15 with Technology & Engineering categories.


Polymeric Gels: Characterization, Properties and Biomedical Applications covers the fundamentals and applications of polymeric gels. Particular emphasis is given to their synthesis, properties and characteristics, with topics such as natural, synthetic, and smart polymeric gels, medical applications, and advancements in conductive and magnetic gels presented. The book covers the basics and applications of hydrogels, providing readers with a comprehensive guide on the types of polymeric gels used in the field of biomedical engineering. Provides guidance for decisions on the suitability and appropriateness of a synthetic route and characterization technique for particular polymeric networks Analyzes and compares experimental data Presents in-depth information on the physical properties of polymeric gels using mathematical models Uses an interdisciplinary approach to discuss potential new applications for both established polymeric gels and recent advances



Nanobiotechnology In Diagnosis Drug Delivery And Treatment


Nanobiotechnology In Diagnosis Drug Delivery And Treatment
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Author : Mahendra Rai
language : en
Publisher: John Wiley & Sons
Release Date : 2020-11-17

Nanobiotechnology In Diagnosis Drug Delivery And Treatment written by Mahendra Rai and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-17 with Science categories.


Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.



Percutaneous Penetration Enhancers Drug Penetration Into Through The Skin


Percutaneous Penetration Enhancers Drug Penetration Into Through The Skin
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Author : Nina Dragicevic
language : en
Publisher: Springer
Release Date : 2017-05-04

Percutaneous Penetration Enhancers Drug Penetration Into Through The Skin written by Nina Dragicevic and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-04 with Medical categories.


Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, students and dermatological scientists or dermatologists​.



Transdermal Drug Delivery Systems


Transdermal Drug Delivery Systems
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Author : Jonathan Hadgraft
language : en
Publisher: CRC Press
Release Date : 2002-10-29

Transdermal Drug Delivery Systems written by Jonathan Hadgraft and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-10-29 with Medical categories.


Presents authoritative state-of-the-art discussions of the key issues pertinent to transdermal drug delivery, examining those topics necessary to enable a critical evaluation of a drug candidate's potential to be delivered across the skin; from physical chemistry and assessment of drug permeability to available enhancement technolgies, to regulator