Somatic Stem Cells
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Somatic Stem Cells
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Author : Shree Ram Singh
language : en
Publisher: Humana Press
Release Date : 2018-09-09
Somatic Stem Cells written by Shree Ram Singh and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-09 with Science categories.
This second edition volume expands on the previous edition with updated discussions on new genetic, molecular, and cellular methods used to study somatic stem cells. The chapters in this book focus on the isolation, classification, purity, and plasticity of these stem cells in a variety of organic tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Somatic Stem Cells: Methods and Protocols, Second Edition is a valuable resource for both novice and experienced molecular biologists, developmental biologists, tissue engineers, and geneticists who are interested in stem cell research and its potentials in regenerative medicine.
Adult Stem Cells
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Author : Kursad Turksen
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-01-27
Adult Stem Cells written by Kursad Turksen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-27 with Science categories.
Studies on stem cells have been attracting intense scientific and p- lic attention, not only because of controversies surrounding the use of embryonic stem cells but also because of very provocative data that have been emerging on adult stem cells. Much of the public attention and debate has been focused on the possibility that adult stem cells may be used as a substitute for human embryonic stem cells or as a justification for stopping work on them. This has somewhat dim- ished attention on very heated scientific debates that take us to the very heart of how the concept of stem cells is perceived. To this author, the latter debates have not been unlike certain philosophical debates of the last century. Since the seminal studies of Till and McCulloch in the 1960s, the popular paradigm on adult stem cells has been that lineage-restricted stem cells are derived from pluripotent stem cells very early during development. To many, and consistent with much data, the restriction to particular lineages was considered absolute. In other words, there was a sense of determinism in the stem quality of particular stem cells: once they were allocated, they were programmed to specific roles in a given tissue. Furthermore, some adult tissues were considered devoid of detectable stem cell presence or activity.
Somatic Stem Cells And Their Plasticity
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Author : Albrecht M. Müller
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2002
Somatic Stem Cells And Their Plasticity written by Albrecht M. Müller and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Adaptation (Physiology) categories.
To the scientist, stem cells offer a precious source of undifferentiated material for the study of cell maturation and specialization. To the clinician, these cells represent a potential source of material for the cure and replacement of damaged organs and tissues. They hold great promise for future therapy: Any disease resulting from genetically or environmentally damaged tissues could, in principle, be repaired through a strategic use of stem cells. 'Somatic Stem Cells and Their Plasticity' contains a timely series of review articles which serve as a primer for basic concepts surrounding stem cell biology. A broad range of topics is explored, including a basic definition of 'stem cell-ness', the genetic control of stem cell longevity, transcriptional regulation of stem cell fate and the debate on tissue stem cell plasticity. Aiming to provide a conceptual scaffold of our current knowledge of stem cell biology, this issue highlights areas of current uncertainty and directs interest towards future experimentation. This publication is of interest to anyone who wishes to gain further insights into current aspects of stem cell biology, as well as to people working with stem cells, such as developmental and molecular biologists and hematologists.
Human Adult Stem Cells
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Author : John Masters
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-05-30
Human Adult Stem Cells written by John Masters and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-30 with Medical categories.
The aim of volume 7 of Human Cell Culture is to provide clear and precise methods for growing primary cultures of adult stem cells from various human tissues and describe culture conditions in which these adult stem cells differentiate along their respective lineages. The book will be of value to biomedical scientists and of special interest to stem cell biologists and tissue engineers. Each chapter is written by experts actively involved in growing human adult stem cells.
Stem Cells And Cell Therapy
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Author : Mohamed Al-Rubeai
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-01
Stem Cells And Cell Therapy written by Mohamed Al-Rubeai and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-01 with Medical categories.
With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.
Adult Stem Cells
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Author : Donald G. Phinney
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-02-11
Adult Stem Cells written by Donald G. Phinney and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-11 with Science categories.
This is comprehensive overview of a vital area of scientific enquiry, which covers a broad spectrum of issues. With contributions from some of the key researchers in the field, Adult Stem Cells: Biology and Methods of Analysis offers readers a historical perspective as well as unique insights into cutting-edge thoughts. The volume contextualizes the recent discovery of stem/progenitor cell populations resident in many adult tissues and organs. It confronts the complexities scientists face in trying to validate these cells, while it also describes and critically evaluates the methods currently used to assess stem cell self-renewal. The chapters also seek to distinguish this process from other aspects of cell survival, such as the regulation of life span, senescence, and immortalization at a molecular level. The monograph begins with a section that examine the basic biology of adult stem cells, including chapters on the emerging role of microRNAs in regulating their fate and the molecular mechanisms that govern their self-renewal, the book moves on to analyze the varying methodologies employed in characterizing these elusive elements of our genetic make-up. The second section details in-vivo lineage tracing of tissue-specific stem cells, explores the neural stem cell paradigm, and considers the function of ABC transporters and aldehyde dehydrogenase in adult stem-cell biology. The final section shifts the focus to the life-span regulation and immortalization and features a chapter on the cancer stem cell paradigm. This is an authoritative volume on one of the frontiers of genetic research, and will serve as a valuable resource, not just for established scientists but also for those now entering the field of stem cell biology.
International Conference Embryonic And Somatic Stem Cells Regenerative Systems For Cell And Tissue Repair
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Author : International Conference Embryonic and Somatic Stem Cells - Regenerative Systems for Cell and Tissue Repair. 2006, Dresden
language : en
Publisher:
Release Date : 2006
International Conference Embryonic And Somatic Stem Cells Regenerative Systems For Cell And Tissue Repair written by International Conference Embryonic and Somatic Stem Cells - Regenerative Systems for Cell and Tissue Repair. 2006, Dresden and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
Stem Cells And The Future Of Regenerative Medicine
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2002-01-25
Stem Cells And The Future Of Regenerative Medicine written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-01-25 with Science categories.
Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Protocols For Adult Stem Cells
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Author : Irina M. Conboy
language : en
Publisher: Humana Press
Release Date : 2011-08-25
Protocols For Adult Stem Cells written by Irina M. Conboy and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-25 with Science categories.
Although embryonic stem cells currently enjoy the public limelight and show great pr- ise for cell based medical therapies, it is the adult stem cells which are responsible for the body’s natural ability to fght disease, heal and recover, or fail and succumb to various maladies. The study of mammalian adult stem cells has surged recently, most likely from a maturation of stem cell studies in the classical developmental model organisms and in hematopoeisis. All the tissues of the body examined so far are generated and regenerated from stem cells, it has been an important frst step to adapt or devise new methods to identify and obtain these cells in quantity and purity for further study. Culture techniques have been optimized for managing the growth and differentiation of stem cells in vitro; as some stem cells are pluripotent, often the method is to guide the fate of such cells among the possible differentiation fates. Much of this work, and that in the classical model org- isms, has helped defne the aspects of the stem cell environment or niche that are crucial for both growth and differentiation, and these studies have moved in vivo at increasingly higher resolution. Importantly, the in vivo niche is a current target for bioengineering the matrix and signaling factors. Herein, we present methods for studying six types of mammalian stem cells, m- mary, neural, mesenchymal, endothelial, dendritic, and muscle.
Stem Cells
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Author : Ariff Bongso
language : en
Publisher: World Scientific
Release Date : 2005
Stem Cells written by Ariff Bongso and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.
Many of the chapters carry extensive self-explanatory figures, colored photographs, graphics and tables."--Jacket.