Spine Phenotypes
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Spine Phenotypes
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Author : Dino Samartzis
language : en
Publisher: Academic Press
Release Date : 2022-07-08
Spine Phenotypes written by Dino Samartzis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-08 with Science categories.
The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance. Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications. Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry. - Book chapters devoted to specific imaging phenotypes with discussion of their clinical correlates - Imaging phenotypes provided with examples of established phenotypic measurements and a range of normal and pathologic images - Multiauthor, multidisciplinary contributions comprising world leaders in the field of spine imaging, research, and clinical practice
Atlas Of Spinal Imaging Phenotypes
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Author : Philip K. Louie
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-03-23
Atlas Of Spinal Imaging Phenotypes written by Philip K. Louie and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-23 with Medical categories.
Spine-related pain is the world's leading disabling condition, affecting every population and a frequent reason for seeking medical consultation and obtaining imaging studies. Numerous spinal phenotypes (observations/traits) and their respective measurements performed on various spine imaging have been shown to directly correlate and predict clinical outcomes. Atlas of Spinal Imaging Phenotypes: Classifications and Radiographic Measurements is a comprehensive visual resource that highlights various spinal phenotypes on imaging, describes their clinical and pathophysiological relevance, and discusses and illustrates their respective measurement techniques and classifications. - Helps readers better understanding spinal phenotypes and their imaging, and how today's knowledge will facilitate new targeted drug discovery, novel diagnostics and biomarker discovery, and outcome predictions. - Features step-by-step instructions on performing the radiographic measurements with examples of normal and pathologic images to demonstrate the various presentations. - Presents clinical correlation of the phenotypes as well as the radiographic measurements with landmark references. - Includes validated classification systems that complement the phenotypes and radiographic measurements. - Complies the knowledge and expertise of Dr. Dino Samartzis, the preeminent global authority on spinal phenotypes who has discovered and proposed new phenotypes and classification schemes; Dr. Howard S. An, a leading expert in patient management and at the forefront of 3D imaging of various spinal phenotypes; and Dr. Philip Louie, a prolific surgeon who is involved in one of the largest machine learning initiatives of spinal phenotyping.
Abnormal Skeletal Phenotypes
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Author : Alessandro Castriota-Scanderbeg
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-20
Abnormal Skeletal Phenotypes written by Alessandro Castriota-Scanderbeg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-20 with Medical categories.
Taking a symptom-oriented approach, this book focuses on the radiographic changes of malformation syndromes and skeletal dysplasias. Its clear structure makes it an essential, practical guide for radiologists, geneticists, and pediatricians.
Factors Affecting Neurological Aging
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Author : Colin R. Martin
language : en
Publisher: Academic Press
Release Date : 2021-06-01
Factors Affecting Neurological Aging written by Colin R. Martin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-01 with Psychology categories.
Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease. - Provides the most comprehensive coverage on a broad range of topics related to the neuroscience of aging - Features sections on the genetic components that influence aging and diseases of aging - Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations - Includes more than 500 illustrations and tables
Neural And Synaptic Defects In Autism Spectrum Disorders
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Author : Hansen Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2015-07-07
Neural And Synaptic Defects In Autism Spectrum Disorders written by Hansen Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-07 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology.
Shaping The Brain By Neuronal Cytoskeleton From Development To Disease And Regeneration
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Author : C. Laura Sayas
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-25
Shaping The Brain By Neuronal Cytoskeleton From Development To Disease And Regeneration written by C. Laura Sayas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-25 with categories.
Down Syndrome From Understanding The Neurobiology To Therapy
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Author : Mara Dierssen
language : en
Publisher: Elsevier
Release Date : 2012-06-19
Down Syndrome From Understanding The Neurobiology To Therapy written by Mara Dierssen and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-19 with Medical categories.
Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system. This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes. It brings together scientists of diverse backgrounds, by facilitating the integration of research directed at different levels of biological organization, and by highlighting translational research and the application of the existing scientific knowledge to develop improved DS treatments and cures. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Issues In Biological And Life Sciences Research 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-05-01
Issues In Biological And Life Sciences Research 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-01 with Science categories.
Issues in Biological and Life Sciences Research: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Issues in Biological and Life Sciences Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological and Life Sciences Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Evolutionary Genetics Of Fishes
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Author : Bruce Turner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Evolutionary Genetics Of Fishes written by Bruce Turner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
It is my hope that this collection of reviews can be profitably read by all who are interested in evolutionary biology. However, I would like to specifically target it for two disparate groups of biologists seldom men tioned in the same sentence, classical ichthyologists and molecular biologists. Since classical times, and perhaps even before, ichthyologists have stood in awe at the tremendous diversity of fishes. The bulk of effort in the field has always been directed toward understanding this diversity, i. e. , extracting from it a coherent picture of evolutionary processes and lineages. This effort has, in turn, always been overwhelmingly based upon morphological comparisons. The practical advantages of such compari sons, especially the ease with which morphological data can be had from preserved museum specimens, are manifold. But considered objectively (outside its context of "tradition"), morphological analysis alone is a poor tool for probing evolutionary processes or elucidating relationships. The concepts of "relationship" and of "evolution" are inherently genetic ones, and the genetic bases of morphological traits are seldom known in detail and frequently unknown entirely. Earlier in this century, several workers, notably Gordon, Kosswig, Schmidt, and, in his salad years, Carl Hubbs, pioneered the application of genetic techniques and modes of reasoning to ichthyology. While certain that most contemporary ichth yologists are familiar with this body of work, I am almost equally certain that few of them regard it as pertinent to their own efforts.
Somitogenesis
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Author : Miguel Maroto
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-10
Somitogenesis written by Miguel Maroto and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-10 with Medical categories.
This book will be of interest to scientists working in the fields of cell and developmental biology. The chapters cover topics that capture the spirit of this dynamic discipline by integrating contemporary research with the classical embryological literature.