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Statistical Analysis Of Clinical Data On A Pocket Calculator


Statistical Analysis Of Clinical Data On A Pocket Calculator
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Statistical Analysis Of Clinical Data On A Pocket Calculator Part 2


Statistical Analysis Of Clinical Data On A Pocket Calculator Part 2
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Author : Ton J. Cleophas
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-28

Statistical Analysis Of Clinical Data On A Pocket Calculator Part 2 written by Ton J. Cleophas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-28 with Medical categories.


The first part of this title contained all statistical tests relevant to starting clinical investigations, and included tests for continuous and binary data, power, sample size, multiple testing, variability, confounding, interaction, and reliability. The current part 2 of this title reviews methods for handling missing data, manipulated data, multiple confounders, predictions beyond observation, uncertainty of diagnostic tests, and the problems of outliers. Also robust tests, non-linear modeling , goodness of fit testing, Bhatacharya models, item response modeling, superiority testing, variability testing, binary partitioning for CART (classification and regression tree) methods, meta-analysis, and simple tests for incident analysis and unexpected observations at the workplace and reviewed. Each test method is reported together with (1) a data example from practice, (2) all steps to be taken using a scientific pocket calculator, and (3) the main results and their interpretation. Although several of the described methods can also be carried out with the help of statistical software, the latter procedure will be considerably slower. Both part 1 and 2 of this title consist of a minimum of text and this will enhance the process of mastering the methods. Yet the authors recommend that for a better understanding of the test procedures the books be used together with the same authors' textbook "Statistics Applied to Clinical Studies" 5th edition edited 2012, by Springer Dordrecht Netherlands. More complex data files like data files with multiple treatment modalities or multiple predictor variables can not be analyzed with a pocket calculator. We recommend that the small books "SPSS for starters", Part 1 and 2 (Springer, Dordrecht, 2010, and 2012) from the same authors be used as a complementary help for the readers' benefit.



Statistical Analysis Of Clinical Data On A Pocket Calculator


Statistical Analysis Of Clinical Data On A Pocket Calculator
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Author : Ton J. Cleophas
language : en
Publisher: Springer
Release Date : 2011-05-06

Statistical Analysis Of Clinical Data On A Pocket Calculator written by Ton J. Cleophas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-06 with Medical categories.


The core principles of statistical analysis are too easily forgotten in today’s world of powerful computers and time-saving algorithms. This step-by-step primer takes researchers who lack the confidence to conduct their own analyses right back to basics, allowing them to scrutinize their own data through a series of rapidly executed reckonings on a simple pocket calculator. A range of easily navigable tutorials facilitate the reader’s assimilation of the techniques, while a separate chapter on next generation Flash prepares them for future developments in the field. This practical volume also contains tips on how to deny hackers access to Flash internet sites. An ideal companion to the author’s co-authored works on statistical analysis for Springer such as Statistics Applied to Clinical Trials, this monograph will help researchers understand the processes involved in interpreting clinical data, as well as being a necessary prerequisite to mastering more advanced statistical techniques. The principles of statistical analysis are easily forgotten in today’s world of time-saving algorithms. This step-by-step primer takes researchers back to basics, enabling them to examine their own data through a series of sums on a simple pocket calculator.



Statistical Analysis Of Clinical Data On A Pocket Calculator


Statistical Analysis Of Clinical Data On A Pocket Calculator
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Author : Ton J. Cleophas
language : en
Publisher:
Release Date : 2011-04-29

Statistical Analysis Of Clinical Data On A Pocket Calculator written by Ton J. Cleophas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-29 with categories.




Clinical Data Analysis On A Pocket Calculator


Clinical Data Analysis On A Pocket Calculator
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Author : Ton J. Cleophas
language : en
Publisher: Springer
Release Date : 2016-01-22

Clinical Data Analysis On A Pocket Calculator written by Ton J. Cleophas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-22 with Medical categories.


In medical and health care the scientific method is little used, and statistical software programs are experienced as black box programs producing lots of p-values, but little answers to scientific questions. The pocket calculator analyses appears to be, particularly, appreciated, because they enable medical and health professionals and students for the first time to understand the scientific methods of statistical reasoning and hypothesis testing. So much so, that it can start something like a new dimension in their professional world. In addition, a number of statistical methods like power calculations and required sample size calculations can be performed more easily on a pocket calculator, than using a software program. Also, there are some specific advantages of the pocket calculator method. You better understand what you are doing. The pocket calculator works faster, because far less steps have to be taken, averages can be used. The current nonmathematical book is complementary to the nonmathematical "SPSS for Starters and 2nd Levelers" (Springer Heidelberg Germany 2015, from the same authors), and can very well be used as its daily companion.



Machine Learning In Medicine


Machine Learning In Medicine
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Author : Ton J. Cleophas
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-05-30

Machine Learning In Medicine written by Ton J. Cleophas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-30 with Medical categories.


Machine learning is concerned with the analysis of large data and multiple variables. However, it is also often more sensitive than traditional statistical methods to analyze small data. The first volume reviewed subjects like optimal scaling, neural networks, factor analysis, partial least squares, discriminant analysis, canonical analysis, and fuzzy modeling. This second volume includes various clustering models, support vector machines, Bayesian networks, discrete wavelet analysis, genetic programming, association rule learning, anomaly detection, correspondence analysis, and other subjects. Both the theoretical bases and the step by step analyses are described for the benefit of non-mathematical readers. Each chapter can be studied without the need to consult other chapters. Traditional statistical tests are, sometimes, priors to machine learning methods, and they are also, sometimes, used as contrast tests. To those wishing to obtain more knowledge of them, we recommend to additionally study (1) Statistics Applied to Clinical Studies 5th Edition 2012, (2) SPSS for Starters Part One and Two 2012, and (3) Statistical Analysis of Clinical Data on a Pocket Calculator Part One and Two 2012, written by the same authors, and edited by Springer, New York.



Regression Analysis In Medical Research


Regression Analysis In Medical Research
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Author : Ton J. Cleophas
language : en
Publisher: Springer
Release Date : 2018-01-29

Regression Analysis In Medical Research written by Ton J. Cleophas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-29 with Science categories.


This edition is a pretty complete textbook and tutorial for medical and health care students, as well as a recollection/update bench, and help desk for professionals. Novel approaches already applied in published clinical research will be addressed: matrix analyses, alpha spending, gate keeping, kriging, interval censored regressions, causality regressions, canonical regressions, quasi-likelihood regressions, novel non-parametric regressions. Each chapter can be studied as a stand-alone, and covers one field in the fast growing world of regression analyses. The authors, as professors in statistics and machine learning at European universities, are worried, that their students find regression-analyses harder than any other methodology in statistics. This is serious, because almost all of the novel methodologies in current data mining and data analysis include elements of regression-analysis. It is the main incentive for writing this 28 chapter edition, consistent of - 28 major fields of regression analysis, - their condensed maths, - their applications in medical and health research as published so far, - step by step analyses for self-assessment, - conclusion and reference sections. Traditional regression analysis is adequate for epidemiology, but lacks the precision required for clinical investigations. However, in the past two decades modern regression methods have proven to be much more precise. And so it is time, that a book described regression analyses for clinicians. The current edition is the first to do so. It is written for a non-mathematical readership. Self-assessment data-files are provided through Springer' s "Extras Online".



Machine Learning In Medicine


Machine Learning In Medicine
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Author : Ton J. Cleophas
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-26

Machine Learning In Medicine written by Ton J. Cleophas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-26 with Medical categories.


Machine learning is concerned with the analysis of large data and multiple variables. It is also often more sensitive than traditional statistical methods to analyze small data. The first and second volumes reviewed subjects like optimal scaling, neural networks, factor analysis, partial least squares, discriminant analysis, canonical analysis, fuzzy modeling, various clustering models, support vector machines, Bayesian networks, discrete wavelet analysis, association rule learning, anomaly detection, and correspondence analysis. This third volume addresses more advanced methods and includes subjects like evolutionary programming, stochastic methods, complex sampling, optional binning, Newton's methods, decision trees, and other subjects. Both the theoretical bases and the step by step analyses are described for the benefit of non-mathematical readers. Each chapter can be studied without the need to consult other chapters. Traditional statistical tests are, sometimes, priors to machine learning methods, and they are also, sometimes, used as contrast tests. To those wishing to obtain more knowledge of them, we recommend to additionally study (1) Statistics Applied to Clinical Studies 5th Edition 2012, (2) SPSS for Starters Part One and Two 2012, and (3) Statistical Analysis of Clinical Data on a Pocket Calculator Part One and Two 2012, written by the same authors, and edited by Springer, New York.



Spss For Starters Part 2


Spss For Starters Part 2
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Author : Ton J. Cleophas
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-09

Spss For Starters Part 2 written by Ton J. Cleophas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-09 with Medical categories.


The first part of this title contained all statistical tests that are relevant for starters on SPSS, and included standard parametric and non-parametric tests for continuous and binary variables, regression methods, trend tests, and reliability and validity assessments of diagnostic tests. The current part 2 of this title reviews multistep methods, multivariate models, assessments of missing data, performance of diagnostic tests, meta-regression, Poisson regression, confounding and interaction, and survival analyses using log tests and segmented time-dependent Cox regression. Methods for assessing non linear models, data seasonality, distribution free methods, including Monte Carlo methods and artificial intelligence, and robust tests are also covered. Each method of testing is explained using a data example from clinical practice,including every step in SPSS, and a text with interpretations of the results and hints convenient for data reporting. In order to facilitate the use of this cookbook the data files of the examples is made available by the editor through extras.springer.com. Both part 1 and 2 of this title contain a minima amount of text and maximal technical details, but we believe that this property will not refrain students from mastering the SPSS software systematics, and that, instead, it will be a help to that aim. Yet, we recommend that it will used together with the textbook "Statistics Applied to Clinical Trials" (5th edition, Springer, Dordrecht 2012) and the e-books "Statistics on a Pocket Calculator Part 1 and 2 (Springer, Dordrecht, 2011 and 2012) from the same authors.



Understanding Clinical Data Analysis


Understanding Clinical Data Analysis
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Author : Ton J. Cleophas
language : en
Publisher: Springer
Release Date : 2016-08-23

Understanding Clinical Data Analysis written by Ton J. Cleophas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.


This textbook consists of ten chapters, and is a must-read to all medical and health professionals, who already have basic knowledge of how to analyze their clinical data, but still, wonder, after having done so, why procedures were performed the way they were. The book is also a must-read to those who tend to submerge in the flood of novel statistical methodologies, as communicated in current clinical reports, and scientific meetings. In the past few years, the HOW-SO of current statistical tests has been made much more simple than it was in the past, thanks to the abundance of statistical software programs of an excellent quality. However, the WHY-SO may have been somewhat under-emphasized. For example, why do statistical tests constantly use unfamiliar terms, like probability distributions, hypothesis testing, randomness, normality, scientific rigor, and why are Gaussian curves so hard, and do they make non-mathematicians getting lost all the time? The book will cover the WHY-SOs.



Modern Bayesian Statistics In Clinical Research


Modern Bayesian Statistics In Clinical Research
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Author : Ton J. Cleophas
language : en
Publisher: Springer
Release Date : 2018-07-31

Modern Bayesian Statistics In Clinical Research written by Ton J. Cleophas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-31 with Medical categories.


The current textbook has been written as a help to medical / health professionals and students for the study of modern Bayesian statistics, where posterior and prior odds have been replaced with posterior and prior likelihood distributions. Why may likelihood distributions better than normal distributions estimate uncertainties of statistical test results? Nobody knows for sure, and the use of likelihood distributions instead of normal distributions for the purpose has only just begun, but already everybody is trying and using them. SPSS statistical software version 25 (2017) has started to provide a combined module entitled Bayesian Statistics including almost all of the modern Bayesian tests (Bayesian t-tests, analysis of variance (anova), linear regression, crosstabs etc.). Modern Bayesian statistics is based on biological likelihoods, and may better fit clinical data than traditional tests based normal distributions do. This is the first edition to systematically imply modern Bayesian statistics in traditional clinical data analysis. This edition also demonstrates that Markov Chain Monte Carlo procedures laid out as Bayesian tests provide more robust correlation coefficients than traditional tests do. It also shows that traditional path statistics are both textually and conceptionally like Bayes theorems, and that structural equations models computed from them are the basis of multistep regressions, as used with causal Bayesian networks.