Statistical Methods Computing And Resources For Genome Wide Association Studies

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Statistical Methods Computing And Resources For Genome Wide Association Studies
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Author : Riyan Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-24
Statistical Methods Computing And Resources For Genome Wide Association Studies written by Riyan Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-24 with Science categories.
Proceedings Of The 2011 2nd International Congress On Computer Applications And Computational Science
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Author : Ford Lumban Gaol
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-23
Proceedings Of The 2011 2nd International Congress On Computer Applications And Computational Science written by Ford Lumban Gaol and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-23 with Technology & Engineering categories.
The latest inventions in computer technology influence most of human daily activities. In the near future, there is tendency that all of aspect of human life will be dependent on computer applications. In manufacturing, robotics and automation have become vital for high quality products. In education, the model of teaching and learning is focusing more on electronic media than traditional ones. Issues related to energy savings and environment is becoming critical. Computational Science should enhance the quality of human life, not only solve their problems. Computational Science should help humans to make wise decisions by presenting choices and their possible consequences. Computational Science should help us make sense of observations, understand natural language, plan and reason with extensive background knowledge. Intelligence with wisdom is perhaps an ultimate goal for human-oriented science. This book is a compilation of some recent research findings in computer application and computational science. This book provides state-of-the-art accounts in Computer Control and Robotics, Computers in Education and Learning Technologies, Computer Networks and Data Communications, Data Mining and Data Engineering, Energy and Power Systems, Intelligent Systems and Autonomous Agents, Internet and Web Systems, Scientific Computing and Modeling, Signal, Image and Multimedia Processing, and Software Engineering.
Research In Computational Molecular Biology
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Author : Minghua Deng
language : en
Publisher: Springer
Release Date : 2013-03-12
Research In Computational Molecular Biology written by Minghua Deng and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Computers categories.
This book constitutes the refereed proceedings of the 17th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2013, held in Beijing, China, in April 2013. The 32 revised full papers were carefully reviewed and selected from 167 submissions. The papers cover a wide range of topics including molecular sequence analysis; genes and regulatory elements; molecular evolution; gene expression; biological networks; sequencing and genotyping technologies; genomics; epigenomics; metagenomics; population, statistical genetics; systems biology; computational proteomics; computational structural biology; imaging; large-scale data management.
Bioinformatics And Biomedical Engineering
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Author : Francisco Ortuño
language : en
Publisher: Springer
Release Date : 2015-03-16
Bioinformatics And Biomedical Engineering written by Francisco Ortuño and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-16 with Computers categories.
The two volume set LNCS 9043 and 9044 constitutes the refereed proceedings of the Third International Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2015, held in Granada, Spain, in April 2015. The 135 papers presented were carefully reviewed and selected from 268 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases, biomedical engineering, biomedical image analysis, biomedical signal analysis, computational genomics, computational proteomics, computational systems for modelling biological processes, e Health, next generation sequencing and sequence analysis, quantitative and systems pharmacology, Hidden Markov Model (HMM) for biological sequence modeling, advances in computational intelligence for bioinformatics and biomedicine, tools for next generation sequencing data analysis, dynamics networks in system medicine, interdisciplinary puzzles of measurements in biological systems, biological networks, high performance computing in bioinformatics, computational biology and computational chemistry, advances in drug discovery and ambient intelligence for bio emotional computing.
Medical Image Computing And Computer Assisted Intervention Miccai 2023
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Author : Hayit Greenspan
language : en
Publisher: Springer Nature
Release Date : 2023-09-30
Medical Image Computing And Computer Assisted Intervention Miccai 2023 written by Hayit Greenspan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-30 with Computers categories.
The ten-volume set LNCS 14220, 14221, 14222, 14223, 14224, 14225, 14226, 14227, 14228, and 14229 constitutes the refereed proceedings of the 26th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2023, which was held in Vancouver, Canada, in October 2023. The 730 revised full papers presented were carefully reviewed and selected from a total of 2250 submissions. The papers are organized in the following topical sections: Part I: Machine learning with limited supervision and machine learning – transfer learning; Part II: Machine learning – learning strategies; machine learning – explainability, bias, and uncertainty; Part III: Machine learning – explainability, bias and uncertainty; image segmentation; Part IV: Image segmentation; Part V: Computer-aided diagnosis; Part VI: Computer-aided diagnosis; computational pathology; Part VII: Clinical applications – abdomen; clinicalapplications – breast; clinical applications – cardiac; clinical applications – dermatology; clinical applications – fetal imaging; clinical applications – lung; clinical applications – musculoskeletal; clinical applications – oncology; clinical applications – ophthalmology; clinical applications – vascular; Part VIII: Clinical applications – neuroimaging; microscopy; Part IX: Image-guided intervention, surgical planning, and data science; Part X: Image reconstruction and image registration.
The Soybean Genome
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Author : Henry T. Nguyen
language : en
Publisher: Springer
Release Date : 2017-09-20
The Soybean Genome written by Henry T. Nguyen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-20 with Science categories.
This book examines the application of soybean genome sequences to comparative, structural, and functional genomics. Since the availability of the soybean genome sequence has revolutionized molecular research on this important crop species, the book also describes how the genome sequence has shaped research on transposon biology and applications for gene identification, tilling and positional gene cloning. Further, the book shows how the genome sequence influences research in the areas of genetic mapping, marker development, and genome-wide association mapping for identifying important trait genes and soybean breeding. In closing, the economic and botanical aspects of the soybean are also addressed.
Advances In Statistical Methods For The Genetic Dissection Of Complex Traits In Plants
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Author : Yuan-Ming Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-26
Advances In Statistical Methods For The Genetic Dissection Of Complex Traits In Plants written by Yuan-Ming Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-26 with Science categories.
Genome-wide association studies (GWAS) have been widely used in the genetic dissection of complex traits. However, there are still limits in current GWAS statistics. For example, (1) almost all the existing methods do not estimate additive and dominance effects in quantitative trait nucleotide (QTN) detection; (2) the methods for detecting QTN-by-environment interaction (QEI) are not straightforward and do not estimate additive and dominance effects as well as additive-by-environment and dominance-by-environment interaction effects, leading to unreliable results; and (3) no or too simple polygenic background controls have been employed in QTN-by-QTN interaction (QQI) detection. As a result, few studies of QEI and QQI for complex traits have been reported based on multiple-environment experiments. Recently, new statistical tools, including 3VmrMLM, have been developed to address these needs in GWAS. In 3VmrMLM, all the trait-associated effects, including QTN, QEI and QQI related effects, are compressed into a single effect-related vector, while all the polygenic backgrounds are compressed into a single polygenic effect matrix. These compressed parameters can be accurately and efficiently estimated through a unified mixed model analysis. To further validate these new GWAS methods, particularly 3VmrMLM, they should be rigorously tested in real data of various plants and a wide range of other species.
Metagenomics
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Author : Muniyandi Nagarajan
language : en
Publisher: Academic Press
Release Date : 2017-10-29
Metagenomics written by Muniyandi Nagarajan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-29 with Medical categories.
Metagenomics: Perspectives, Methods, and Applications provides thorough coverage of the growing field of metagenomics. A diverse range of chapters from international experts offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools, and recent metagenomic studies in various environments. The emphasis on application makes this text particularly useful for applied researchers, practitioners, clinicians and students seeking to employ metagenomic approaches to advance knowledge in the biomedical and life sciences. Case-study based application chapters examine topics ranging from viral metagenome profiling, metagenomics in oral disease and health, metagenomic insights into the human gut microbiome and metabolic syndromes, and more. Additionally, perspectives on future potential at the end of each chapter provoke new thought and motivations for continued study in this exciting and fruitful research area. - Provides thorough coverage of the rapidly growing field of metagenomics, with an emphasis on applications of relevance to translational researchers, practitioners, clinicians and students - Features a diverse range of chapters from international experts that offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools and research pipelines - Highlights perspectives on future potential at the end of each chapter to provoke new thought and motivations for continued study in this exciting and fruitful research area
Oxford Textbook Of Global Public Health
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Author : Roger Detels
language : en
Publisher: Oxford University Press
Release Date : 2022
Oxford Textbook Of Global Public Health written by Roger Detels and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Medical categories.
Invaluable for all practitioners, trainees, and students of public health and epidemiology, the Oxford Textbook of Global Public Health covers the scope, methods, and practice of public health and has been comprehensively updated for its seventh edition.
Statistical Inference From High Dimensional Data
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Author : Carlos Fernandez-Lozano
language : en
Publisher: MDPI
Release Date : 2021-04-28
Statistical Inference From High Dimensional Data written by Carlos Fernandez-Lozano and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-28 with Science categories.
• Real-world problems can be high-dimensional, complex, and noisy • More data does not imply more information • Different approaches deal with the so-called curse of dimensionality to reduce irrelevant information • A process with multidimensional information is not necessarily easy to interpret nor process • In some real-world applications, the number of elements of a class is clearly lower than the other. The models tend to assume that the importance of the analysis belongs to the majority class and this is not usually the truth • The analysis of complex diseases such as cancer are focused on more-than-one dimensional omic data • The increasing amount of data thanks to the reduction of cost of the high-throughput experiments opens up a new era for integrative data-driven approaches • Entropy-based approaches are of interest to reduce the dimensionality of high-dimensional data