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Statistical Methods For Environmental Epidemiology With R


Statistical Methods For Environmental Epidemiology With R
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Statistical Methods For Environmental Epidemiology With R


Statistical Methods For Environmental Epidemiology With R
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Author : Roger D. Peng
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-15

Statistical Methods For Environmental Epidemiology With R written by Roger D. Peng and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-15 with Medical categories.


As an area of statistical application, environmental epidemiology and more speci cally, the estimation of health risk associated with the exposure to - vironmental agents, has led to the development of several statistical methods and software that can then be applied to other scienti c areas. The stat- tical analyses aimed at addressing questions in environmental epidemiology have the following characteristics. Often the signal-to-noise ratio in the data is low and the targets of inference are inherently small risks. These constraints typically lead to the development and use of more sophisticated (and pot- tially less transparent) statistical models and the integration of large hi- dimensional databases. New technologies and the widespread availability of powerful computing are also adding to the complexities of scienti c inves- gation by allowing researchers to t large numbers of models and search over many sets of variables. As the number of variables measured increases, so do the degrees of freedom for in uencing the association between a risk factor and an outcome of interest. We have written this book, in part, to describe our experiences developing and applying statistical methods for the estimation for air pollution health e ects. Our experience has convinced us that the application of modern s- tistical methodology in a reproducible manner can bring to bear subst- tial bene ts to policy-makers and scientists in this area. We believe that the methods described in this book are applicable to other areas of environmental epidemiology, particularly those areas involving spatial{temporal exposures.



Statistical Methods In Environmental Epidemiology


Statistical Methods In Environmental Epidemiology
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Author : Duncan C. Thomas
language : en
Publisher: OUP Oxford
Release Date : 2009-02-26

Statistical Methods In Environmental Epidemiology written by Duncan C. Thomas and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-26 with Science categories.


Environmental epidemiology is the study of the environmental causes of disease in populations and how these risks vary in relation to intensity and duration of exposure and other factors like genetic susceptibility. As such, it is the basic science upon which governmental safety standards and compensation policies for environmental and occupational exposure are based. Profusely illustrated with examples from the epidemiologic literature on ionizing radiation and air pollution, this text provides a systematic treatment of the statistical challenges that arise in environmental health studies and the use epidemiologic data in formulating public policy, at a level suitable for graduate students and epidemiologic researchers. After a general overview of study design and statistical methods for epidemiology generally, the book goes on to address the problems that are unique to environmental health studies, special-purpose designs like two-phase case-control studies and countermatching, statistical methods for modeling exposure-time-response relationships, longitudinal and time-series studies, spatial and ecologic methods, exposure measurement error, interactions, and mechanistic models. It also discusses studies aimed at evaluating the public health benefits of interventions to improve the environment, the use of epidemiologic data to establish environmental safety standards and compensation policy, and concludes with emerging problems in reproductive epidemiology, natural and man-made disasters like global warming, and the global burden of environmentally caused disease. No other book provides such a broad perspective on the methodological challenges in this field at a level accessible to both epidemiologists and statisticians.



Statistical Methods In Environmental Epidemiology


Statistical Methods In Environmental Epidemiology
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Author : Duncan C. Thomas
language : en
Publisher: Oxford University Press, USA
Release Date : 2009

Statistical Methods In Environmental Epidemiology written by Duncan C. Thomas and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.


A systematic treatment of the statistical challenges that arise in environmental health studies and the use epidemiologic data in formulating public policy, at a level suitable for graduate students and epidemiologic researchers.



Statistical Methods For Environmental Mixtures


Statistical Methods For Environmental Mixtures
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Author : Andrea Bellavia
language : en
Publisher: Springer Nature
Release Date : 2025-01-27

Statistical Methods For Environmental Mixtures written by Andrea Bellavia and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-27 with Medical categories.


This book provides a comprehensive introduction to statistical approaches for the assessment of complex environmental exposures, such as pollutants and chemical mixtures, within the exposome framework. Environmental mixtures are defined as groups of 3 or more chemical/pollutants, simultaneously present in nature, consumer products, or in the human body. Assessing the health effects of environmental mixtures poses several methodological challenges due to the high levels of correlation that are often present between environmental chemicals, and by the need of incorporating flexible non-additive and non-linear effects that can capture and describe the complex mechanisms by which environmental exposure contribute to diseases. Several statistical approaches are proposed and discussed, including the application of regression-based approaches (e.g. penalized regression such as LASSO and elastic net, or Bayesian variable selection) for environmental exposures, and novel methods (e.g. weighted quantile sum regression, or Bayesian Kernel Machine Regression) that account for specific complexities of environmental exposures. More recent efforts included are the application of machine learning approaches (e.g. gradient boosting) for environmental data. Statistical Methods for Environmental Mixtures describes the statistical challenges that commonly arise when dealing with environmental exposures and provides an introduction to different statistical approaches for such data. Over the last decade, substantial efforts have been made to transition the statistical framework for environmental exposures in epidemiologic studies from a single-chemical/pollutant to a multi-chemicals/pollutants approach. This book provides a comprehensive introduction to this modern multi-chemicals/pollutants framework. Emphasis is given to interpretability, discussing issues with causal interpretation and translation of scientific finding when applying the discussed statistical approaches for complex environmental exposures. The target audience includes researchers in environmental epidemiology and applied statisticians working in the field. As such, while rigorously presenting the statistical methodologies, the book keeps an applied focus, discussing those settings where each method is appropriate for use and for which question it can be applied, providing examples of accurate presentation and interpretation from the literature, including a basic introduction to R packages and tutorials, as well as discussing assumptions and practical challenges when applying these techniques on real data.



Statistical Data Analysis Explained


Statistical Data Analysis Explained
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Author : Clemens Reimann
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-31

Statistical Data Analysis Explained written by Clemens Reimann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-31 with Science categories.


Few books on statistical data analysis in the natural sciences are written at a level that a non-statistician will easily understand. This is a book written in colloquial language, avoiding mathematical formulae as much as possible, trying to explain statistical methods using examples and graphics instead. To use the book efficiently, readers should have some computer experience. The book starts with the simplest of statistical concepts and carries readers forward to a deeper and more extensive understanding of the use of statistics in environmental sciences. The book concerns the application of statistical and other computer methods to the management, analysis and display of spatial data. These data are characterised by including locations (geographic coordinates), which leads to the necessity of using maps to display the data and the results of the statistical methods. Although the book uses examples from applied geochemistry, and a large geochemical survey in particular, the principles and ideas equally well apply to other natural sciences, e.g., environmental sciences, pedology, hydrology, geography, forestry, ecology, and health sciences/epidemiology. The book is unique because it supplies direct access to software solutions (based on R, the Open Source version of the S-language for statistics) for applied environmental statistics. For all graphics and tables presented in the book, the R-scripts are provided in the form of executable R-scripts. In addition, a graphical user interface for R, called DAS+R, was developed for convenient, fast and interactive data analysis. Statistical Data Analysis Explained: Applied Environmental Statistics with R provides, on an accompanying website, the software to undertake all the procedures discussed, and the data employed for their description in the book.



Spatio Temporal Methods In Environmental Epidemiology With R


Spatio Temporal Methods In Environmental Epidemiology With R
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Author : Gavin Shaddick
language : en
Publisher: CRC Press
Release Date : 2023-12-12

Spatio Temporal Methods In Environmental Epidemiology With R written by Gavin Shaddick and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-12 with Medical categories.


Spatio-Temporal Methods in Environmental Epidemiology with R, like its First Edition, explores the interface between environmental epidemiology and spatio-temporal modeling. It links recent developments in spatio-temporal theory with epidemiological applications. Drawing on real-life problems, it shows how recent advances in methodology can assess the health risks associated with environmental hazards. The book's clear guidelines enable the implementation of the methodology and estimation of risks in practice. New additions to the Second Edition include: a thorough exploration of the underlying concepts behind knowledge discovery through data; a new chapter on extracting information from data using R and the tidyverse; additional material on methods for Bayesian computation, including the use of NIMBLE and Stan; new methods for performing spatio-temporal analysis and an updated chapter containing further topics. Throughout the book there are new examples, and the presentation of R code for examples has been extended. Along with these additions, the book now has a GitHub site (https://spacetime-environ.github.io/stepi2) that contains data, code and further worked examples. Features: • Explores the interface between environmental epidemiology and spatio-temporal modeling • Incorporates examples that show how spatio-temporal methodology can inform societal concerns about the effects of environmental hazards on health • Uses a Bayesian foundation on which to build an integrated approach to spatio-temporal modeling and environmental epidemiology • Discusses data analysis and topics such as data visualization, mapping, wrangling and analysis • Shows how to design networks for monitoring hazardous environmental processes and the ill effects of preferential sampling • Through the listing and application of code, shows the power of R, tidyverse, NIMBLE and Stan and other modern tools in performing complex data analysis and modeling Representing a continuing important direction in environmental epidemiology, this book – in full color throughout – underscores the increasing need to consider dependencies in both space and time when modeling epidemiological data. Readers will learn how to identify and model patterns in spatio-temporal data and how to exploit dependencies over space and time to reduce bias and inefficiency when estimating risks to health.



Spatio Temporal Methods In Environmental Epidemiology


Spatio Temporal Methods In Environmental Epidemiology
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Author : Gavin Shaddick
language : en
Publisher: CRC Press
Release Date : 2015-06-17

Spatio Temporal Methods In Environmental Epidemiology written by Gavin Shaddick and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-17 with Mathematics categories.


Teaches Students How to Perform Spatio-Temporal Analyses within Epidemiological StudiesSpatio-Temporal Methods in Environmental Epidemiology is the first book of its kind to specifically address the interface between environmental epidemiology and spatio-temporal modeling. In response to the growing need for collaboration between statisticians and



Biostatistics For Epidemiology And Public Health Using R


Biostatistics For Epidemiology And Public Health Using R
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Author : Bertram K.C. Chan
language : en
Publisher: Springer Publishing Company
Release Date : 2015-11-05

Biostatistics For Epidemiology And Public Health Using R written by Bertram K.C. Chan and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-05 with Medical categories.


Since it first appeared in 1996, the open-source programming language R has become increasingly popular as an environment for statistical analysis and graphical output. In addition to being freely available, R offers several advantages for biostatistics, including strong graphics capabilities, the ability to write customized functions, and its extensibility. This is the first textbook to present classical biostatistical analysis for epidemiology and related public health sciences to students using the R language. Based on the assumption that readers have minimal familiarity with statistical concepts, the author uses a step-bystep approach to building skills. The text encompasses biostatistics from basic descriptive and quantitative statistics to survival analysis and missing data analysis in epidemiology. Illustrative examples, including real-life research problems and exercises drawn from such areas as nutrition, environmental health, and behavioral health, engage students and reinforce the understanding of R. These examples illustrate the replication of R for biostatistical calculations and graphical display of results. The text covers both essential and advanced techniques and applications in biostatistics that are relevant to epidemiology. This text is supplemented with teaching resources, including an online guide for students in solving exercises and an instructor's manual. KEY FEATURES: First overview biostatistics textbook for epidemiology and public health that uses the open-source R program Covers essential and advanced techniques and applications in biostatistics as relevant to epidemiology Features abundant examples and exercises to illustrate the application of R language for biostatistical calculations and graphical displays of results Includes online student solutions guide and instructor's manual



Statistical Methods For Global Health And Epidemiology


Statistical Methods For Global Health And Epidemiology
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Author : Xinguang Chen
language : en
Publisher: Springer Nature
Release Date : 2020-04-13

Statistical Methods For Global Health And Epidemiology written by Xinguang Chen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-13 with Medical categories.


This book examines statistical methods and models used in the fields of global health and epidemiology. It includes methods such as innovative probability sampling, data harmonization and encryption, and advanced descriptive, analytical and monitory methods. Program codes using R are included as well as real data examples. Contemporary global health and epidemiology involves a myriad of medical and health challenges, including inequality of treatment, the HIV/AIDS epidemic and its subsequent control, the flu, cancer, tobacco control, drug use, and environmental pollution. In addition to its vast scales and telescopic perspective; addressing global health concerns often involves examining resource-limited populations with large geographic, socioeconomic diversities. Therefore, advancing global health requires new epidemiological design, new data, and new methods for sampling, data processing, and statistical analysis. This book provides global health researchers with methods that will enable access to and utilization of existing data. Featuring contributions from both epidemiological and biostatistical scholars, this book is a practical resource for researchers, practitioners, and students in solving global health problems in research, education, training, and consultation.



Handbook Of Environmental And Ecological Statistics


Handbook Of Environmental And Ecological Statistics
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Author : Alan E. Gelfand
language : en
Publisher: CRC Press
Release Date : 2019-01-15

Handbook Of Environmental And Ecological Statistics written by Alan E. Gelfand and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-15 with Mathematics categories.


This handbook focuses on the enormous literature applying statistical methodology and modelling to environmental and ecological processes. The 21st century statistics community has become increasingly interdisciplinary, bringing a large collection of modern tools to all areas of application in environmental processes. In addition, the environmental community has substantially increased its scope of data collection including observational data, satellite-derived data, and computer model output. The resultant impact in this latter community has been substantial; no longer are simple regression and analysis of variance methods adequate. The contribution of this handbook is to assemble a state-of-the-art view of this interface. Features: An internationally regarded editorial team. A distinguished collection of contributors. A thoroughly contemporary treatment of a substantial interdisciplinary interface. Written to engage both statisticians as well as quantitative environmental researchers. 34 chapters covering methodology, ecological processes, environmental exposure, and statistical methods in climate science.