Statistical Modelling In Biostatistics And Bioinformatics
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Statistical Modelling In Biostatistics And Bioinformatics
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Author : Gilbert MacKenzie
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-05-08
Statistical Modelling In Biostatistics And Bioinformatics written by Gilbert MacKenzie and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-08 with Mathematics categories.
This book presents selected papers on statistical model development related mainly to the fields of Biostatistics and Bioinformatics. The coverage of the material falls squarely into the following categories: (a) Survival analysis and multivariate survival analysis, (b) Time series and longitudinal data analysis, (c) Statistical model development and (d) Applied statistical modelling. Innovations in statistical modelling are presented throughout each of the four areas, with some intriguing new ideas on hierarchical generalized non-linear models and on frailty models with structural dispersion, just to mention two examples. The contributors include distinguished international statisticians such as Philip Hougaard, John Hinde, Il Do Ha, Roger Payne and Alessandra Durio, among others, as well as promising newcomers. Some of the contributions have come from researchers working in the BIO-SI research programme on Biostatistics and Bioinformatics, centred on the Universities of Limerick and Galway in Ireland and funded by the Science Foundation Ireland under its Mathematics Initiative.
Handbook Of Statistical Bioinformatics
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Author : Henry Horng-Shing Lu
language : en
Publisher: Springer Nature
Release Date : 2022-12-08
Handbook Of Statistical Bioinformatics written by Henry Horng-Shing Lu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-08 with Science categories.
Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.
Advances In Statistical Bioinformatics
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Author : Kim-Anh Do
language : en
Publisher: Cambridge University Press
Release Date : 2013-06-10
Advances In Statistical Bioinformatics written by Kim-Anh Do and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-10 with Medical categories.
Providing genome-informed personalized treatment is a goal of modern medicine. Identifying new translational targets in nucleic acid characterizations is an important step toward that goal. The information tsunami produced by such genome-scale investigations is stimulating parallel developments in statistical methodology and inference, analytical frameworks, and computational tools. Within the context of genomic medicine and with a strong focus on cancer research, this book describes the integration of high-throughput bioinformatics data from multiple platforms to inform our understanding of the functional consequences of genomic alterations. This includes rigorous and scalable methods for simultaneously handling diverse data types such as gene expression array, miRNA, copy number, methylation, and next-generation sequencing data. This material is written for statisticians who are interested in modeling and analyzing high-throughput data. Chapters by experts in the field offer a thorough introduction to the biological and technical principles behind multiplatform high-throughput experimentation.
Bioinformatics And Computational Biology Solutions Using R And Bioconductor
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Author : Robert Gentleman
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-12-29
Bioinformatics And Computational Biology Solutions Using R And Bioconductor written by Robert Gentleman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-29 with Computers categories.
Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Modern Statistics For Modern Biology
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Author : Susan Holmes
language : en
Publisher:
Release Date : 2019
Modern Statistics For Modern Biology written by Susan Holmes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
Statistical Bioinformatics
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Author : Jae K. Lee
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-20
Statistical Bioinformatics written by Jae K. Lee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-20 with Medical categories.
This book provides an essential understanding of statistical concepts necessary for the analysis of genomic and proteomic data using computational techniques. The author presents both basic and advanced topics, focusing on those that are relevant to the computational analysis of large data sets in biology. Chapters begin with a description of a statistical concept and a current example from biomedical research, followed by more detailed presentation, discussion of limitations, and problems. The book starts with an introduction to probability and statistics for genome-wide data, and moves into topics such as clustering, classification, multi-dimensional visualization, experimental design, statistical resampling, and statistical network analysis. Clearly explains the use of bioinformatics tools in life sciences research without requiring an advanced background in math/statistics Enables biomedical and life sciences researchers to successfully evaluate the validity of their results and make inferences Enables statistical and quantitative researchers to rapidly learn novel statistical concepts and techniques appropriate for large biological data analysis Carefully revisits frequently used statistical approaches and highlights their limitations in large biological data analysis Offers programming examples and datasets Includes chapter problem sets, a glossary, a list of statistical notations, and appendices with references to background mathematical and technical material Features supplementary materials, including datasets, links, and a statistical package available online Statistical Bioinformatics is an ideal textbook for students in medicine, life sciences, and bioengineering, aimed at researchers who utilize computational tools for the analysis of genomic, proteomic, and many other emerging high-throughput molecular data. It may also serve as a rapid introduction to the bioinformatics science for statistical and computational students and audiences who have not experienced such analysis tasks before.
Statistical Models In S
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Author : T.J. Hastie
language : en
Publisher: Routledge
Release Date : 2017-11-01
Statistical Models In S written by T.J. Hastie and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-01 with Mathematics categories.
Statistical Models in S extends the S language to fit and analyze a variety of statistical models, including analysis of variance, generalized linear models, additive models, local regression, and tree-based models. The contributions of the ten authors-most of whom work in the statistics research department at AT&T Bell Laboratories-represent results of research in both the computational and statistical aspects of modeling data.
Regression Modeling Strategies
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Author : Frank E. Harrell
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Regression Modeling Strategies written by Frank E. Harrell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Mathematics categories.
Many texts are excellent sources of knowledge about individual statistical tools, but the art of data analysis is about choosing and using multiple tools. Instead of presenting isolated techniques, this text emphasizes problem solving strategies that address the many issues arising when developing multivariable models using real data and not standard textbook examples. It includes imputation methods for dealing with missing data effectively, methods for dealing with nonlinear relationships and for making the estimation of transformations a formal part of the modeling process, methods for dealing with "too many variables to analyze and not enough observations," and powerful model validation techniques based on the bootstrap. This text realistically deals with model uncertainty and its effects on inference to achieve "safe data mining".
Statistical Modeling For Biomedical Researchers
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Author : William D. Dupont
language : en
Publisher: Cambridge University Press
Release Date : 2009-02-12
Statistical Modeling For Biomedical Researchers written by William D. Dupont and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-12 with Medical categories.
A second edition of the easy-to-use standard text guiding biomedical researchers in the use of advanced statistical methods.
Statistical Modeling In Biomedical Research
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Author : Yichuan Zhao
language : en
Publisher: Springer Nature
Release Date : 2020-03-19
Statistical Modeling In Biomedical Research written by Yichuan Zhao and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-19 with Medical categories.
This edited collection discusses the emerging topics in statistical modeling for biomedical research. Leading experts in the frontiers of biostatistics and biomedical research discuss the statistical procedures, useful methods, and their novel applications in biostatistics research. Interdisciplinary in scope, the volume as a whole reflects the latest advances in statistical modeling in biomedical research, identifies impactful new directions, and seeks to drive the field forward. It also fosters the interaction of scholars in the arena, offering great opportunities to stimulate further collaborations. This book will appeal to industry data scientists and statisticians, researchers, and graduate students in biostatistics and biomedical science. It covers topics in: Next generation sequence data analysis Deep learning, precision medicine, and their applications Large scale data analysis and its applications Biomedical research and modeling Survival analysis with complex data structure and its applications.