Statistical Techniques In Bioassay
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Statistical Techniques In Bioassay
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Author : Z. Govindarajulu
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2001-01-03
Statistical Techniques In Bioassay written by Z. Govindarajulu and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-03 with Medical categories.
In the face of the ever-increasing importance of statistical methods in medical research and practice, the first edition of this publication has provided a sound and deep understanding of statistical methods in bioassay to many students and researchers. In addition to the profound presentation of statistical methods of the first edition, here the reader will find new material stemming from the recent statistical literature as well as data reflecting modern trends in general applied statistical research. Examples are discussions on design and planning, e.g. choices of dose levels, an additional section in the chapter on Bayes methods, and a new chapter on sequential estimation for the logistic model. The book will be a valuable source of information to students in the experimental area of statistical aspects of biological assay, professional statisticians with an interest in research in this topic, teachers in statistics and biology, and investigators in the biological and medical sciences who use bioassay in their work.
Statistical Techniques In Bioassay
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Author : Z. Govindarajulu
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2001
Statistical Techniques In Bioassay written by Z. Govindarajulu and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Science categories.
In the face of the ever-increasing importance of statistical methods in medical research and practice, the first edition of this publication has provided a sound and deep understanding of statistical methods in bioassay to many students and researchers. In addition to the profound presentation of statistical methods of the first edition, here the reader will find new material stemming from the recent statistical literature as well as data reflecting modern trends in general applied statistical research. Examples are discussions on design and planning, e.g. choices of dose levels, and additional section in the chapter on Bayes methods, and a new chapter on sequential estimation for the logistic model. The book will be a valuable source of information to students in the experimental area of statistical aspects of biological assay, professional statisticians with an interest in research in this topic, teachers in statistics and biology, and investigators in the biological and medical sciences who use bioassay in their work.
Statistical Method In Biological Assay
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Author : David John Finney
language : en
Publisher:
Release Date : 1952
Statistical Method In Biological Assay written by David John Finney and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1952 with Biological assay categories.
The Statistics Of Bioassay
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Author : C. I. Bliss
language : en
Publisher: Elsevier
Release Date : 2014-05-12
The Statistics Of Bioassay written by C. I. Bliss and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.
The Statistics of Bioassay: With Special Reference to the Vitamins, Volume II focuses on the processes, reactions, principles, and approaches involved in the biological assay of vitamins. The publication first offers information on the general principles of biological assay, dosage-response curve and its error, and designs for segregating nonrandom variation. Discussions focus on replacement of missing values, randomized groups, calculation of the line, analysis of the variation about the line, comparative biological assays, analytical biological assays, and determination of activity. The text then ponders on measurement of relative potency and correction of quantitative variables. The manuscript takes a look at assays where the variation in response is a function of the dose and slope-ratio assays. Topics include microbiological assays and the slope-ratio technique, analysis of balanced slope-ratio assays, analysis of assays with an all-or-none response, and graded response with unequal variance. The publication then tackles multiple or repeated assays, including quality control in repeated assays and combination of independent assays of a single unknown. The publication is a valuable source of information for researchers interested in the biological assay of vitamins.
Statistical Method In Biological Assay
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Author : David John Finney
language : en
Publisher:
Release Date : 1971
Statistical Method In Biological Assay written by David John Finney and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Biological assay categories.
Statistical Theory And Analysis In Bioassay
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Author : Uchenna Petronilla Ogoke
language : en
Publisher: IPS Intelligentsia Publishing Services
Release Date : 2021-08-21
Statistical Theory And Analysis In Bioassay written by Uchenna Petronilla Ogoke and has been published by IPS Intelligentsia Publishing Services this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-21 with Medical categories.
Statistical Theory and Analysis in Bioassay is a seven chapter monograph tailored essentially to meet the needs of graduate students, practitioners and researchers in the fields of medicine, pharmacology, biosciences/life sciences and related fields that employs the tools of biostatistics in bioassays and analysis. In this wise, we have taken time to discuss in details relevant topics; principles, methods and applications. Practice exercises are also included where necessary. The earlier chapters give background information, definition of terms, purpose, types, structure and relative potency in bioassay. An important theorem, Fieller’s theorem is proved in details with illustrative examples. The last two chapters are on dose-response relationship, fitting in parallelline assays and estimation. We are convinced that this monograph will meet the expectations of the readers while constructive criticisms that will improve another edition will be appreciated.
Biostatistics For Bioassay
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Author : Ann Yellowlees
language : en
Publisher: CRC Press
Release Date : 2024-12-24
Biostatistics For Bioassay written by Ann Yellowlees and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-24 with Mathematics categories.
In recent decades, there has been enormous growth in biologics research and development, with the accompanying development of biological assays for emerging products. In parallel, there have been substantial advances in statistical methodology, as well as technological advances in computer power, enabling new techniques to be implemented via statistical software. Biostatistics for Bioassay presents an overview of the statistical analysis techniques that are needed in order to report the results of biological assays. These assays are needed for testing all biological medicines, such as vaccines and cell therapies, to allow them to be released for use. Beginning with consideration of the performance characteristics required of a bioassay, including accuracy, precision, and combinations of these two attributes, the book builds a framework for statistical bioassay design. Features: Explains the statistical methods needed at each stage of the lifecycle of a bioassay Describes the demonstration of the bioassay’s performance, known as validation Covers the statistical techniques for monitoring the bioassay’s performance over time Details how to transfer the bioassay to another laboratory or replace critical reagents Provides examples at every stage, to allow the reader to work through the techniques and consolidate their understanding The book provides a resource for interested bioassay analysts, and statisticians working with bioassays. In bringing together best practices in statistics across the bioassay lifecycle into a single volume, it aims to provide a comprehensive and useful textbook for statistical analysis in bioassay.
Methods And Applications Of Statistics In The Life And Health Sciences
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Author : Narayanaswamy Balakrishnan
language : en
Publisher: John Wiley & Sons
Release Date : 2009-12-02
Methods And Applications Of Statistics In The Life And Health Sciences written by Narayanaswamy Balakrishnan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-02 with Mathematics categories.
Inspired by the Encyclopedia of Statistical Sciences, Second Edition, this volume outlines the statistical tools for successfully working with modern life and health sciences research Data collection holds an essential part in dictating the future of health sciences and public health, as the compilation of statistics allows researchers and medical practitioners to monitor trends in health status, identify health problems, and evaluate the impact of health policies and programs. Methods and Applications of Statistics in the Life and Health Sciences serves as a single, one-of-a-kind resource on the wide range of statistical methods, techniques, and applications that are applied in modern life and health sciences in research. Specially designed to present encyclopedic content in an accessible and self-contained format, this book outlines thorough coverage of the underlying theory and standard applications to research in related disciplines such as biology, epidemiology, clinical trials, and public health. Uniquely combining established literature with cutting-edge research, this book contains classical works and more than twenty-five new articles and completely revised contributions from the acclaimed Encyclopedia of Statistical Sciences, Second Edition. The result is a compilation of more than eighty articles that explores classic methodology and new topics, including: Sequential methods in biomedical research Statistical measures of human quality of life Change-point methods in genetics Sample size determination for clinical trials Mixed-effects regression models for predicting pre-clinical disease Probabilistic and statistical models for conception Statistical methods are explored and applied to population growth, disease detection and treatment, genetic and genomic research, drug development, clinical trials, screening and prevention, and the assessment of rehabilitation, recovery, and quality of life. These topics are explored in contributions written by more than 100 leading academics, researchers, and practitioners who utilize various statistical practices, such as election bias, survival analysis, missing data techniques, and cluster analysis for handling the wide array of modern issues in the life and health sciences. With its combination of traditional methodology and newly developed research, Methods and Applications of Statistics in the Life and Health Sciences has everything students, academics, and researchers in the life and health sciences need to build and apply their knowledge of statistical methods and applications.
Bioassay Techniques For Drug Development
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Author : Atta-ur-Rahman
language : en
Publisher: CRC Press
Release Date : 2001-10-04
Bioassay Techniques For Drug Development written by Atta-ur-Rahman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-04 with Medical categories.
The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassa
Introduction To Statistical Analysis Of Laboratory Data
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Author : Alfred Bartolucci
language : en
Publisher: John Wiley & Sons
Release Date : 2015-12-02
Introduction To Statistical Analysis Of Laboratory Data written by Alfred Bartolucci and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-02 with Mathematics categories.
Introduction to Statistical Analysis of Laboratory Data presents a detailed discussion of important statistical concepts and methods of data presentation and analysis Provides detailed discussions on statistical applications including a comprehensive package of statistical tools that are specific to the laboratory experiment process Introduces terminology used in many applications such as the interpretation of assay design and validation as well as “fit for purpose” procedures including real world examples Includes a rigorous review of statistical quality control procedures in laboratory methodologies and influences on capabilities Presents methodologies used in the areas such as method comparison procedures, limit and bias detection, outlier analysis and detecting sources of variation Analysis of robustness and ruggedness including multivariate influences on response are introduced to account for controllable/uncontrollable laboratory conditions