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Statistics For Microarrays

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Statistics For Microarrays

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Author : Ernst Wit
language : en
Publisher: John Wiley & Sons
Release Date : 2004-11-19

Statistics For Microarrays written by Ernst Wit and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-19 with Mathematics categories.

Interest in microarrays has increased considerably in the last ten years. This increase in the use of microarray technology has led to the need for good standards of microarray experimental notation, data representation, and the introduction of standard experimental controls, as well as standard data normalization and analysis techniques. Statistics for Microarrays: Design, Analysis and Inference is the first book that presents a coherent and systematic overview of statistical methods in all stages in the process of analysing microarray data – from getting good data to obtaining meaningful results. Provides an overview of statistics for microarrays, including experimental design, data preparation, image analysis, normalization, quality control, and statistical inference. Features many examples throughout using real data from microarray experiments. Computational techniques are integrated into the text. Takes a very practical approach, suitable for statistically-minded biologists. Supported by a Website featuring colour images, software, and data sets. Primarily aimed at statistically-minded biologists, bioinformaticians, biostatisticians, and computer scientists working with microarray data, the book is also suitable for postgraduate students of bioinformatics.

Statistics And Data Analysis For Microarrays Using R And Bioconductor

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Author : Sorin Draghici
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Statistics And Data Analysis For Microarrays Using R And Bioconductor written by Sorin Draghici and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Computers categories.

Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that teaches students the basics of R and microarray technology as well as how to choose and apply the proper data analysis tool to specific problems. New to the Second EditionCompletely updated and double the size of its predecessor, this timely second edition replaces the commercial software with the open source R and Bioconductor environments. Fourteen new chapters cover such topics as the basic mechanisms of the cell, reliability and reproducibility issues in DNA microarrays, basic statistics and linear models in R, experiment design, multiple comparisons, quality control, data pre-processing and normalization, Gene Ontology analysis, pathway analysis, and machine learning techniques. Methods are illustrated with toy examples and real data and the R code for all routines is available on an accompanying downloadable resource. With all the necessary prerequisites included, this best-selling book guides students from very basic notions to advanced analysis techniques in R and Bioconductor. The first half of the text presents an overview of microarrays and the statistical elements that form the building blocks of any data analysis. The second half introduces the techniques most commonly used in the analysis of microarray data.

Statistical Analysis Of Gene Expression Microarray Data

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Author : Terry Speed
language : en
Publisher: CRC Press
Release Date : 2003-03-26

Statistical Analysis Of Gene Expression Microarray Data written by Terry Speed and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-26 with Mathematics categories.

Although less than a decade old, the field of microarray data analysis is now thriving and growing at a remarkable pace. Biologists, geneticists, and computer scientists as well as statisticians all need an accessible, systematic treatment of the techniques used for analyzing the vast amounts of data generated by large-scale gene expression studies

Dna Methylation Microarrays

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Author : Sun-Chong Wang
language : en
Publisher: CRC Press
Release Date : 2008-04-24

Dna Methylation Microarrays written by Sun-Chong Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-24 with Mathematics categories.

Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in particular, DNA methylation microarray data. Since these microarrays share the same under

Analyzing Microarray Gene Expression Data

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Author : Geoffrey J. McLachlan
language : en
Publisher: John Wiley & Sons
Release Date : 2005-02-18

Analyzing Microarray Gene Expression Data written by Geoffrey J. McLachlan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-02-18 with Mathematics categories.

A multi-discipline, hands-on guide to microarray analysis of biological processes Analyzing Microarray Gene Expression Data provides a comprehensive review of available methodologies for the analysis of data derived from the latest DNA microarray technologies. Designed for biostatisticians entering the field of microarray analysis as well as biologists seeking to more effectively analyze their own experimental data, the text features a unique interdisciplinary approach and a combined academic and practical perspective that offers readers the most complete and applied coverage of the subject matter to date. Following a basic overview of the biological and technical principles behind microarray experimentation, the text provides a look at some of the most effective tools and procedures for achieving optimum reliability and reproducibility of research results, including: An in-depth account of the detection of genes that are differentially expressed across a number of classes of tissues Extensive coverage of both cluster analysis and discriminant analysis of microarray data and the growing applications of both methodologies A model-based approach to cluster analysis, with emphasis on the use of the EMMIX-GENE procedure for the clustering of tissue samples The latest data cleaning and normalization procedures The uses of microarray expression data for providing important prognostic information on the outcome of disease

Statistics For Microarrays

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Author : Ernst Wit
language : en
Publisher: John Wiley & Sons
Release Date : 2004-07-23

Microarray Data Analysis

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Author : Giuseppe Agapito
language : en
Publisher: Humana
Release Date : 2022-12-15

Microarray Data Analysis written by Giuseppe Agapito and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-15 with Science categories.

This meticulous book explores the leading methodologies, techniques, and tools for microarray data analysis, given the difficulty of harnessing the enormous amount of data. The book includes examples and code in R, requiring only an introductory computer science understanding, and the structure and the presentation of the chapters make it suitable for use in bioinformatics courses. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of key detail and expert implementation advice that ensures successful results and reproducibility. Authoritative and practical, Microarray Data Analysis is an ideal guide for students or researchers who need to learn the main research topics and practitioners who continue to work with microarray datasets.

Microarray Bioinformatics

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Author : Dov Stekel
language : en
Publisher: Cambridge University Press
Release Date : 2003-09-08

Microarray Bioinformatics written by Dov Stekel and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-08 with Medical categories.

This book is a comprehensive guide to all of the mathematics, statistics and computing you will need to successfully operate DNA microarray experiments. It is written for researchers, clinicians, laboratory heads and managers, from both biology and bioinformatics backgrounds, who work with, or who intend to work with microarrays. The book covers all aspects of microarray bioinformatics, giving you the tools to design arrays and experiments, to analyze your data, and to share your results with your organisation or with the international community. There are chapters covering sequence databases, oligonucleotide design, experimental design, image processing, normalisation, identifying differentially expressed genes, clustering, classification and data standards. The book is based on the highly successful Microarray Bioinformatics course at Oxford University, and therefore is ideally suited for teaching the subject at postgraduate or professional level.

Dna Microarrays And Related Genomics Techniques

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Author : David B. Allison
language : en
Publisher: CRC Press
Release Date : 2005-11-14

Dna Microarrays And Related Genomics Techniques written by David B. Allison and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-14 with Mathematics categories.

Considered highly exotic tools as recently as the late 1990s, microarrays are now ubiquitous in biological research. Traditional statistical approaches to design and analysis were not developed to handle the high-dimensional, small sample problems posed by microarrays. In just a few short years the number of statistical papers providing approaches

The Analysis Of Gene Expression Data

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Author : Giovanni Parmigiani
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11

The Analysis Of Gene Expression Data written by Giovanni Parmigiani and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.

This book presents practical approaches for the analysis of data from gene expression micro-arrays. It describes the conceptual and methodological underpinning for a statistical tool and its implementation in software. The book includes coverage of various packages that are part of the Bioconductor project and several related R tools. The materials presented cover a range of software tools designed for varied audiences.

Statistics For Microarrays

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