Stem Cell And Gene Therapy For Cardiovascular Disease
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Stem Cell And Gene Therapy For Cardiovascular Disease
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Author : Emerson c. Perin
language : en
Publisher: Academic Press
Release Date : 2015-08-21
Stem Cell And Gene Therapy For Cardiovascular Disease written by Emerson c. Perin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-21 with Medical categories.
Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials. Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic. Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI Covers the prevailing opinions on how to harness the body’s natural repair mechanisms Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals
Gene Therapy For Cardiovascular Diseases And Arrhythmia
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Author : Kamilla Kelemen
language : en
Publisher: Nova Science Publishers
Release Date : 2012
Gene Therapy For Cardiovascular Diseases And Arrhythmia written by Kamilla Kelemen and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Arrhythmia categories.
Cardiovascular disease has evolved into an epidemic health concern. During the past decades, considerable effort has been made to develop novel and safer therapeutic options. Gene therapy has offered much renewed hope and instigated the present book. For the treatment of cardiovascular disease gene therapy has risen to an interesting and important point of view of curing disease. Although most of the studies are still experimental beneath a well defined number of clinical studies, more and more studies are designed to be carried out in humans. Based on a rich compilation of scientific as well as clinical studies around the world, this book gives insights into the general principles of gene transfer as well as therapeutic strategies including stem cell therapy as an alternative approach to gene therapy.
Gene Therapy For Cardiovascular Diseases And Arrhythmia
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Author : Kamilla Kelemen
language : en
Publisher: Nova Science Publishers
Release Date : 2012
Gene Therapy For Cardiovascular Diseases And Arrhythmia written by Kamilla Kelemen and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Arrhythmia categories.
Cardiovascular disease has evolved into an epidemic health concern. During the past decades, considerable effort has been made to develop novel and safer therapeutic options. Gene therapy has offered much renewed hope and instigated the present book. For the treatment of cardiovascular disease gene therapy has risen to an interesting and important point of view of curing disease. Although most of the studies are still experimental beneath a well defined number of clinical studies, more and more studies are designed to be carried out in humans. Based on a rich compilation of scientific as well as clinical studies around the world, this book gives insights into the general principles of gene transfer as well as therapeutic strategies including stem cell therapy as an alternative approach to gene therapy.
Molecular Cardiology
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Author : Zhongjie Sun
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01
Molecular Cardiology written by Zhongjie Sun and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Medical categories.
The aim of Molecular Cardiology: Methods and Protocols is to document state-of-the-art molecular and genetic techniques in the area of cardiology. These modern approaches enable researchers to readily study heart diseases at the molecular level and will promote the development of new therapeutic str- egies. Methods for genetic dissection, signal transduction, and microarray analysis are excellent tools for the study of the molecular mechanisms of cardiovascular diseases. Protocols for transgenesis take advantage of recent advances in many areas of molecular and cell biology. Transgenic models of heart diseases (cardiac hypertrophy, cardiac dysfunction, and so on. ) are powerful tools for the study of heart disease pathogenesis. Methods for gene transfer to heart tissue using viral and nonviral vectors form the basis of gene therapy for heart diseases. Heart-specific promoters containing a hypox- inducible cardioprotective gene switch are key for protection of the heart from ischemia. Gene and stem cell therapies open novel and exciting avenues for the prevention and treatment of heart diseases. Molecular Cardiology: Methods and Protocols consists of 26 chapters de- ing with various aspects of molecular cardiology, including gene transfer and gene therapy for cardiovascular disease, stem cell therapy for cardiovascular disease, gene analysis in the injured and hypertrophied heart, and transgenesis in cardiovascular research. This book provides step-by-step methods for the successful completion of experimental procedures, and would be useful for both experienced and new investigators in the field of molecular cardiology.
Regenerating The Heart
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Author : Ira S. Cohen
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-03-23
Regenerating The Heart written by Ira S. Cohen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-23 with Science categories.
Medical research made huge strides in treating heart disease in the 20th century, from drug-eluding stents to automatic internal defibrillators. Public awareness of the dangers of heart disease has never been more pervasive. Now, though, ten years into a new millennium, scientists are gearing up for the next great challenges in tackling this pervasive condition. Cell therapy is going to be a key weapon in the fight against heart disease. It has the potential to address many cardiovascular conditions. From heart failure to atrioventricular nodal dysfunction, the young but promising field of cell therapy is set to play a significant role in developing the cures that the upcoming decades of hard work will yield. Regenerating the Heart: Stem Cells and the Cardiovascular System organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies. An array of talented researchers share the fruits of their labors, with chapters covering such crucial issues as the cardiogenic potential of varying stem cell types, the ways in which they might be used to tackle arrhythmias, their possible application to biological replacements for cardiac tissues such as valves, and the varying approaches used in the in vivo evaluation of stem cell therapies, including methods of delivering stem cells to the myocardium. This comprehensive survey of an area of research with such exciting potential is an invaluable resource both for veteran stem cell researchers who need to monitor fresh developments, and for newly minted investigators seeking inspirational examples.
Cardiac Cell And Gene Transfer
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Author : Joseph M. Metzger
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03
Cardiac Cell And Gene Transfer written by Joseph M. Metzger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Medical categories.
Heart disease is the leading cause of death in developed countries. Recent experimental advances featuring cellular, molecular, and genetic tools and technologies offer the potential for new therapeutic strategies directed toward remediation of inherited and acquired heart diseases. Whether these recent basic science advances will ultimately translate to clinical efficacy for patients with heart disease is unknown and is important to ascertain. Cardiac Cell and Gene Transfer: Principles, Protocols, and Applications is designed to provide the reader with up-to-date coverage of a myriad of specific methodo- gies and protocols for gene and cell transfer to the myocardium. Each chapter features a “Notes” section that provides useful “how to” problem-solving insights that are often left unstated in standard published protocols. Cardiac Cell and Gene Transfer: Principles, Protocols, and Appli- tions addresses principles and applications of cell and gene transfer to the heart, including protocols for vector production and purification. Detailed step-by-step methods and applications for first/second-generation adenoviral vectors, adeno-associated vectors, gutted adenoviral vectors, and lentiviral vectors are included. Additionally, detailed methods for cardiac cell grafting and transplantation are provided, and these chapters highlight the prospects of cell-based therapies for cardiac repair. The book also covers specific in vivo techniques for cardiac gene transfer, and specifies subsequent cellular and organ-level physiological assessment techniques and protocols. Accordingly, this book is designed for basic science and clinical researchers in the academic, pharmaceutical, and biotechnology sectors of the cardiovascular community.
Stem Cell Therapy And Tissue Engineering For Cardiovascular Repair
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Author : Nabil Dib
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-09
Stem Cell Therapy And Tissue Engineering For Cardiovascular Repair written by Nabil Dib and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-09 with Technology & Engineering categories.
In excess of 7 million people worldwide die of coronary heart disease each year. Only one-third of these heart attack victims recover completely. The remainder suffer the consequences of myocardial infarction and its ill fated remodeling process, resulting in chronic congestive heart failure. This malady alone is the leading cause of hospital admissions in the United States. New breakthroughs in stem cell therapy and tissue engineering have promised to reverse this dismal outcome by cardiovascular repair. World authorities, including scientists and regulatory authorities, have joined in a collaborative effort to present for the reader the first collective review of stem cell therapy for the treatment of cardiovascular disease. These contributions in basic science, pre-clinical and clinical experience guided by the regulatory pathways, assure a rapid course of translational research and clinical trials. The contents of this publication will become a prerequisite for those preparing to meet the challenges of this exciting and potentially rewarding field of stem cell research.
Applications Of Biotechnology In Cardiovascular Therapeutics
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Author : Kewal K. Jain
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-07-25
Applications Of Biotechnology In Cardiovascular Therapeutics written by Kewal K. Jain and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-25 with Science categories.
For physicians, surgeons, and scientists working on cardiovascular disorders, Applications of Biotechnology in Cardiovascular Therapeutics serves as an invaluable reference by collecting the essential writings of Dr. Kewal K. Jain on the topics of biotechnology as they relate to cardiovascular disease. This thorough volume includes such subjects as biotechnology and therapeutic delivery to the cardiovascular system, cell-selective targeted drug delivery, cell and gene therapies, including antisense and RNA interference, cutting-edge gene therapy approaches, as well as personalized cardiology as a way of integrating new technologies into the selection of the best possible treatment for an individual patient. Selected references from recent literature are collected for each chapter, and the text is supplemented by a variety of useful tables and figures. Comprehensive and up-to-date, Applications of Biotechnology in Cardiovascular Therapeutics will be tremendously useful for those working in life sciences and the pharmaceutical sciences, and the inclusion of some basics of cardiovascular diseases will greatly benefit nonmedical readers as well.
Pioneering Stem Cell Gene Therapy Trials
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Author : Roger Bertolotti
language : en
Publisher: CRC Press
Release Date : 2003-10-15
Pioneering Stem Cell Gene Therapy Trials written by Roger Bertolotti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-15 with Science categories.
The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinical trials are the focus of this book. Therapy successes such as the X-SCID trial and improved ADA-SCID ones are presented together with pioneering angio/vasculogenic clinical trials mediated either by transient gene
Handbook Of Cardiac Stem Cell Therapy
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Author : Ioannis Dimarakis
language : en
Publisher: Imperial College Press
Release Date : 2009-01-01
Handbook Of Cardiac Stem Cell Therapy written by Ioannis Dimarakis and has been published by Imperial College Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-01 with Medical categories.
This book is an impressive compilation of contributions on the hot topic of cardiac stem cell therapy from leading groups all over the world. In the assembly of chapters, a structured approach is adopted; starting from the clinician's perspective, all developments in both the experimental and clinical research areas are covered. This journey will take the reader from the bench-top to the bedside, with all chapters written by leading authorities in their respective fields, including data still in press with medical journals.