Stem Cell Labeling For Delivery And Tracking Using Noninvasive Imaging
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Stem Cell Labeling For Delivery And Tracking Using Noninvasive Imaging
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Author : Dara L. Kraitchman
language : en
Publisher:
Release Date : 2012
Stem Cell Labeling For Delivery And Tracking Using Noninvasive Imaging written by Dara L. Kraitchman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Molecular probes categories.
"Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward"--Provided by publisher.
Stem Cell Labeling For Delivery And Tracking Using Noninvasive Imaging
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Author : Dara L. Kraitchman
language : en
Publisher: CRC Press
Release Date : 2011-11-18
Stem Cell Labeling For Delivery And Tracking Using Noninvasive Imaging written by Dara L. Kraitchman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-18 with Science categories.
Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward.
Labeling And Detection Of Marrow Derived Mesenchymal Stromal Cells Using Magnetic Resonance Imaging
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Author : Emidio Tarulli
language : en
Publisher:
Release Date : 2008
Labeling And Detection Of Marrow Derived Mesenchymal Stromal Cells Using Magnetic Resonance Imaging written by Emidio Tarulli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Stem Cells In Clinical Practice And Tissue Engineering
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Author : Rakesh Sharma
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-05-02
Stem Cells In Clinical Practice And Tissue Engineering written by Rakesh Sharma and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-02 with Science categories.
Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.
Nanotechnology And Nanomaterials In The Treatment Of Life Threatening Diseases
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Author : Narenda Kumar
language : en
Publisher: William Andrew
Release Date : 2013-12-05
Nanotechnology And Nanomaterials In The Treatment Of Life Threatening Diseases written by Narenda Kumar and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Medical categories.
Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases takes a scientific approach to nanotechnology and nanomaterials applications in medicine, while also explaining the core biological principles for an audience of biomedical engineers, materials scientists, pharmacologists, and medical diagnostic technicians. The book is structured by major disease groups, offering a practical, application-based focus for scientists, engineers, and clinicians alike. The spectrum of medical applications is explored, from diagnostics and imaging to drug delivery, monitoring, therapies, and disease prevention. It also focuses specifically on the synthesis of nanomaterials and their potential health risks (particularly toxicity). Nanomedicine — the application of nanomaterials and devices for addressing medical problems — has demonstrated great potential for enabling improved diagnosis, treatment, and monitoring of many serious illnesses, including cancer, cardiovascular and neurological disorders, HIV/AIDS, and diabetes, as well as many types of inflammatory and infectious diseases. Gain an understanding of how nanotechnologies and nanomaterials can be deployed in the fight against the major life-threatening diseases: cancer, neurological disorders (including Alzheimer's and Parkinson's), cardiovascular diseases, and HIV/AIDS Discover the latest developments in nanomedicine, from therapies and drug delivery to diagnostics and disease prevention The authors cover the health risks of nanomaterials as well as their benefits, considering toxicity and potential carcinogens
Pet Imaging Of Adoptive Progenitor Cell Therapies
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Author :
language : en
Publisher:
Release Date : 2008
Pet Imaging Of Adoptive Progenitor Cell Therapies written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Objectives. The overall objective of this application is to develop novel technologies for non-invasive imaging of adoptive stem cell-based therapies with positron emission tomography (PET) that would be applicable to human patients. To achieve this objective, stem cells will be genetically labeled with a PET-reporter gene and repetitively imaged to assess their distribution, migration, differentiation, and persistence using a radiolabeled reporter probe. This new imaging technology will be tested in adoptive progenitor cell-based therapy models in animals, including: delivery pro-apoptotic genes to tumors, and T-cell reconstitution for immunostimulatory therapy during allogeneic bone marrow progenitor cell transplantation. Technical and Scientific Merits. Non-invasive whole body imaging would significantly aid in the development and clinical implementation of various adoptive progenitor cell-based therapies by providing the means for non-invasive monitoring of the fate of injected progenitor cells over a long period of observation. The proposed imaging approaches could help to address several questions related to stem cell migration and homing, their long-term viability, and their subsequent differentiation. The ability to image these processes non-invasively in 3D and repetitively over a long period of time is very important and will help the development and clinical application of various strategies to control and direct stem cell migration and differentiation. Approach to accomplish the work. Stem cells will be genetically with a reporter gene which will allow for repetitive non-invasive "tracking" of the migration and localization of genetically labeled stem cells and their progeny. This is a radically new approach that is being developed for future human applications and should allow for a long term (many years) repetitive imaging of the fate of tissues that develop from the transplanted stem cells. Why the approach is appropriate. The novel approach to stem cell imaging is proposed to circumvent the major limitation of in vitro radiolabeling - the eventual radiolabel decay. Stable transduction of stem cells in vitro would allow for the selection of high quality stem cells with optimal functional parameters of the transduced reporter systems. The use of a long-lived radioisotope 124I to label a highly specific reporter gene probe will allow for ex vivo labeling of stem cells and their imaging immediately after injection and during the following next week. The use of short-lived radioisotopes (i.e., 18F) to label highly specific reporter gene probes will allow repetitive PET imaging for the assessment of to stem cell migration, targeting, differentiation, and long-term viability of stem cell-derived tissues. Qualifications of the research team and resources. An established research team of experts in various disciplines has been assembled at MD Anderson Cancer Center (MDACC) over the past two years including the PI, senior co-investigators and collaborators. The participants of this team are recognized internationally to be among the leaders in their corresponding fields of research and clinical medicine. The resources at MDACC are exceptionally well developed and have been recently reinforced by the installation of a microPET and microSPECT/CT cameras, and a 7T MRI system for high resolution animal imaging; and by integrating a synthetic chemistry core for the development and production of precursors for radiolabeling.
Stem Cells And Cardiovascular Diseases
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Author : Shijun Hu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-17
Stem Cells And Cardiovascular Diseases written by Shijun Hu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-17 with Science categories.
Handbook Of Small Animal Imaging
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Author : George C. Kagadis
language : en
Publisher: CRC Press
Release Date : 2018-09-03
Handbook Of Small Animal Imaging written by George C. Kagadis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Medical categories.
The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.
Medical Imaging In Clinical Practice
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Author : Okechukwu Felix Erondu
language : en
Publisher: BoD – Books on Demand
Release Date : 2013-02-20
Medical Imaging In Clinical Practice written by Okechukwu Felix Erondu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-20 with Medical categories.
Medical Imaging in Clinical Practice is a compendium of the various applications of imaging modalities in specific clinical conditions. It captures in an easy to read manner, the experiences of various experts drawn from across the globe. It explores the conventional techniques, advanced modalities and on going research efforts in the ever widening horizon of medical imaging. The various topics would be relevant to residents, radiologists and specialists who order and interpret various medical imaging procedures. It is an essential for the inquisitive mind, seeking to understand the scope of medical imaging in clinical practice.
Hematopoietic Stem Cell Transplantation For The Pediatric Hematologist Oncologist
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Author : Valerie I. Brown
language : en
Publisher: Springer
Release Date : 2017-12-22
Hematopoietic Stem Cell Transplantation For The Pediatric Hematologist Oncologist written by Valerie I. Brown and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-22 with Medical categories.
This volume provides a comprehensive and state-of-the-art review on pediatric hematopoietic stem cell transplantation (HSCT). The book covers such topics as graft versus host disease (GVHD), HSC mobilization, stem cell selection, and HSCT-relevant laboratory assays and techniques. The text is specially formatted so that the scientific basis of HSCT and ethical considerations are integrated into the relevant clinical framework. Each chapter also includes diagrams, illustrations, and tables that summarize key points and concepts that can be used as a quick visual reference for the reader. Written by experts in the field, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist is a valuable resource on pediatric HSCT suited for pediatric hematologists-oncologists, fellows, advanced practitioners, clinical nurses, and other referring physicians.