Stem Cells Between Regeneration And Tumorigenesis
DOWNLOAD
Download Stem Cells Between Regeneration And Tumorigenesis PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Stem Cells Between Regeneration And Tumorigenesis book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Stem Cells Between Regeneration And Tumorigenesis
DOWNLOAD
Author : Monica Neagu
language : en
Publisher: Bentham Science Publishers
Release Date : 2016-09-16
Stem Cells Between Regeneration And Tumorigenesis written by Monica Neagu and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-16 with Science categories.
Experts in the field of cellular biology have shown that the reactivation of pluripotency inherent in all cells can allow us to reprogram cells into a specific cell line. This reprogramming paradigm is steadily enhancing our understanding of cell differentiation processes and cellular identity. Consequently, new prospects for cellular therapies of diseases and in vivo regeneration have risen. Stem Cells Between Regeneration and Tumorigenesis focuses on organ specific molecular pathways that trigger two opposite ways that a stem cell can grow (regeneration and neoplasia). Chapters provide a balanced set of information about tissue regeneration and tumorigenesis in several tissues and biological systems (the nervous, circulatory, oral, skin, digestive and endocrine systems). Additional reviews of the immunological role in regulating the two stem cell growth processes and the role of genomics and proteomics in understanding these processes round up the contents of this monograph. Readers of this book will gain the following key benefits: -an insight into the complexity and controversy surrounding the established dual stem cell behavior paradigm (regeneration versus tumorigenesis) -an understanding of the intricate cellular processes such as stem cells maintenance -background knowledge of optimizing tailored therapy in personalized and regenerative medicine Stem Cells Between Regeneration and Tumorigenesis is a useful resource for advanced graduates and researchers undertaking courses in molecular biology and personalized medicine, as well as interns involved in stem cell research programs.
The Stem Cell Microenvironment And Its Role In Regenerative Medicine And Cancer Pathogenesis
DOWNLOAD
Author : Cristian Pablo Pennisi
language : en
Publisher: CRC Press
Release Date : 2022-09-01
The Stem Cell Microenvironment And Its Role In Regenerative Medicine And Cancer Pathogenesis written by Cristian Pablo Pennisi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-01 with Science categories.
How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue engineering is to mimic the natural cell environment by designing very sophisticated scaffolds able not only to mechanically support cells, but also to release signals biologically relevant for governing stem cell fate. In addition, increasing evidence suggests that abnormal interaction of stem cells with their niche is responsible for altered cell function leading to malignant transformation. This book discusses some of the recent advances in stem cell research that may help understanding the properties of the niche that govern stem cell fate. Technical topics discussed include:Stem cell biologyCancer stem cellsStem cell interactions with biomaterialsEngineering the stem cell microenvironmentStem cells in tissue regeneration and repairThe Disputationes Workshop series is an international initiative aimed at disseminating stem cell related cutting edge knowledge among scientists, healthcare workers, students and policy makers. This book emerges as a result of the scientific contributions presented and discussed during the fifth Disputationes Workshop held in Aalborg (Denmark) in April 2014. The stem cell microenvironment and its role in regenerative medicine and cancer pathogenesis is ideal for academic staff and master/research students in biomedical and health sciences
Stem Cell Repair And Regeneration Volume 2
DOWNLOAD
Author : Nagy A Habib
language : en
Publisher: World Scientific
Release Date : 2007-03-06
Stem Cell Repair And Regeneration Volume 2 written by Nagy A Habib and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-06 with Science categories.
This second book in the Stem Cell Repair and Regeneration series provides a deeper exploration of the therapeutic potential of undifferentiated human stem cells.Regenerative medicine is an extremely fast-moving field which is evolving from the initial days of hype and excitement to a more realistic appraisal of the role of stem cells in the treatment of degenerative disorders. The series aims to keep abreast of these changes by combining new knowledge in stem cell biology and therapeutic applications.The current volume contains papers by the field's leading scientists and explores the current knowledge on cell therapy for different diseases and injured organs, including diabetes, liver and heart disease./a
Stem Cells Heterogeneity In Cancer
DOWNLOAD
Author : Alexander Birbrair
language : en
Publisher:
Release Date : 2019
Stem Cells Heterogeneity In Cancer written by Alexander Birbrair and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Stem cells categories.
This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue, for several types of cancers, e.g. glioblastoma stem cells. Recent developments have revealed completely different roles of distinct stem cells within the same organ. Thus, Stem Cells Heterogeneity in Cancer provides a timely update us on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity - Novel Concepts, and Stem Cells Heterogeneity in Different Organs, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.
Stem Cells From Basic Research To Therapy Volume Two
DOWNLOAD
Author : Federico Calegari
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Stem Cells From Basic Research To Therapy Volume Two written by Federico Calegari and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
The second volume in the Stem Cells series concentrates on the mechanisms of stem cell regeneration in the adult organism with a view towards understanding how lost tissue can be replaced during adulthood and aging. The second focus of this volume is on stem cell identification and manipulation, including applications in basic research, medicine, a
Stem Cells
DOWNLOAD
Author : Prasad S. Koka
language : en
Publisher: Nova Science Publishers
Release Date : 2016
Stem Cells written by Prasad S. Koka and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Regeneration (Biology) categories.
Stem cells of varying potencies originating from the organ generating totipotent embryonic stem cells (ESCs) to terminally differented cells such as platelets formation, via pluripotent hematopoietic stem cells (HSCs), and their downstream multipotent mesenchymal stem cells (MSCs), have in general been well characterized. Thus majority of these different stem cell types and their differentiation progeny can be tracked for subjecting to further characterizations for clinical relevance and consequently needed biological modifications at the cellular and molecular levels, for patients clinical treatments. The very first section of this books contents deal with the above stated description. Such characterizations and research laboratory manipulations of the stem cells have led to their clinical grade applications and treatments with positive benefits, as described in the second section of this book. The clinical benefits as published by Nova Science Publishers herein as part of the contents are of tremendous significance and provide relief to the handicapped individuals, particularly for those who suffered lifes biological hazards. This naturally seeks R&D-mediated bench to bedside benefits and solutions for the genetically defective individuals. Bone marrow-derived stem cells with HSCs as their primary components are increasingly being cast the human eyes with pregnant females resorting cord blood banking as they peek to dwell into the future well being of their offspring(s) which could even benefit their own selves, should there be expectedly sufficient HLA matching. The third section of this book deals with such topics. The induced pluripotent stem cells (iPSCs) which were generated to overcome the ethical considerations of using ESCs were fraught with elaborate molecular and cellular biological engineering methods and the advent of derivation and usefulness of MSCs have since sidelined or relegated the iPSCs to a distant role. Nonetheless the hitherto served purpose of iPSCs is not discounted and yet unknown stumbling blocks of what seems to be a smooth going runway of MSCs may spring up in the clinical paths necessitated by the treatment along the future. In the fourth section of the book, it is to be kept in mind that uncontrolled proliferation of cells should be avoided at all costs. Whereas self-renewal of stem cells is generally expected to lead to a turnover, it need not be the case with regeneration processes. This will depend upon the genetic make up of the donor-derived and invasively injected stem cells plus accompanying biological reagent components, as well as also the recipients physical conditions. The fifth and last section of the book deals with conventional and alternative medicine topics applicable to carcinogenesis or such tendencies. Telomerase activity is a double edged sword. Therefore its homeostasis or equilibrium is to be maintained. Discriminatory apoptosis that is of beneficial nature affecting malignant cells but not the normal cells is necessary. Thus equation between apoptotic and telomerase activities even those of stem cells should be as hand in glove.
Stem Cell Repair And Regeneration
DOWNLOAD
Author : Nagy A Habib
language : en
Publisher: World Scientific
Release Date : 2005-09-12
Stem Cell Repair And Regeneration written by Nagy A Habib and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-12 with Science categories.
Stem cell research is one of the leading “cutting edge” areas of life science research in the world today and is a topic of significant interest to a broad range of the medical and scientific community. This authoritative book provides reviews by the field's leading scientists and covers many of the areas in which stem cells are becoming increasingly important, such as in organ repair and regeneration. Stem cells offer the possibility of cell therapy issues to treat a myriad of diseases, conditions, and disabilities including Parkinson's and Alzheimer's diseases, spinal cord injury, stroke, heart disease, and diabetes.
Stem Cells And Cancer Stem Cells Volume 12
DOWNLOAD
Author : M.A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-02-20
Stem Cells And Cancer Stem Cells Volume 12 written by M.A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-20 with Medical categories.
Volume 12 in this series explores the latest experimental and clinical uses of stem cells in the treatment of disease and of injuries and reviews methods for isolating multipotent endothelial-like cells from human adipose tissue and discusses clinical applications in cell therapy and regenerative medicine. The book is organized in five parts: Cancer Stem Cells, Pluripotent Stem Cells, Dendritic Stem Cells, Regenerative Medicine and General Applications. The first section includes chapters on histamine in the neural and cancer stem cell niches and emerging concepts of stem cell organization in the normal lung and in lung cancer. The section on Pluripotent Stem Cells includes discussion of the differentiation of dendritic cells from human induced pluripotent stem cell and the molecular mechanisms involved in reprogramming human somatic cells to generate induced pluripotent stem cells. Additional chapters cover the differentiation of induced pluripotent stem cells into functional cardiomyocytes, characteristics of satellite cells and multipotent adult stem cells in the skeletal muscle. The section on Dendritic Stem Cells explores the critical role of notch signaling in the differentiation and function of dendrite. Other chapters cover hypertensive emergencies in children after stem cell transplantation and overcoming the radio resistance of lung cancer stem cells. The section on Regenerative Medicine reports on experiments on improved renal revascularization in pigs using stem cells and phenotypic correction of murine Hemophilia A using cell-based therapy. The concluding section, General Applications, discusses such topics as methods in mathematical modeling for stem cells, as well as molecular and functional characterization of human adipocytes. Like its eleven predecessors in the series, this volume stands out for its comprehensive approach, its roster of some 51 expert contributors representing a dozen different countries and its up-to-date review of leading-edge technology and methods.
Stem Cell Repair And Regeneration Volume 3
DOWNLOAD
Author : Natasa Levicar
language : en
Publisher: World Scientific
Release Date : 2008-04-29
Stem Cell Repair And Regeneration Volume 3 written by Natasa Levicar and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-29 with Science categories.
Stem cells have generated considerable interest recently in the scientific, clinical, and public arenas. The third book in the Stem Cell Repair and Regeneration series offers contributions from numerous areas bridging medicine and the life sciences.Significant research activities in the tissue engineering or regenerative medicine (the term recently used) field started in the 1970s, and there is currently great excitement over the possibility of replacing damaged body parts through regenerative medicine. Potential strategies to replace, repair and restore the function of damaged tissues or organs include stem cell transplantation, transplantation of tissues engineered in the laboratory, and the induction of regeneration by the body's own cells. It is believed that novel cellular therapeutics outperform any medical device, recombinant protein or chemical compound.This volume explores novel stem cell therapeutic strategies for myriad diseases, including renal failure, retinal disease and myocardial infarction./a
Stem Cells From Myth To Reality And Evolving
DOWNLOAD
Author : Khawaja Husnain Haider
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-09-23
Stem Cells From Myth To Reality And Evolving written by Khawaja Husnain Haider and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-23 with Medical categories.
This book is a continuum of the first two books published in the STEM CELLS series entitled "Stem Cells: From Drug to Drug Discovery" and "Stem Cells: From Hype to Real Hope" which were published in 2017 and 2019, respectively. The scope of the book encompasses a wide range of topics with a latitude from adult stem cells to pluripotent stem cells in regenerative medicine either alone or as part of the combinatorial therapeutic intervention approach as "drug" besides their application as tools (disease model) during drug development process. Written by a leading group of researchers, the book encompasses experimental to clinical aspects of stem/progenitors cells, their biology, and characteristics.