Stem Cells From Myth To Reality And Evolving
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Stem Cells From Myth To Reality And Evolving
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Author : Khawaja Husnain Haider
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-09-23
Stem Cells From Myth To Reality And Evolving written by Khawaja Husnain Haider and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-23 with Medical categories.
This book is a continuum of the first two books published in the STEM CELLS series entitled "Stem Cells: From Drug to Drug Discovery" and "Stem Cells: From Hype to Real Hope" which were published in 2017 and 2019, respectively. The scope of the book encompasses a wide range of topics with a latitude from adult stem cells to pluripotent stem cells in regenerative medicine either alone or as part of the combinatorial therapeutic intervention approach as "drug" besides their application as tools (disease model) during drug development process. Written by a leading group of researchers, the book encompasses experimental to clinical aspects of stem/progenitors cells, their biology, and characteristics.
Handbook Of Stem Cell Therapy
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Author : Khawaja Husnain Haider
language : en
Publisher: Springer Nature
Release Date : 2022-11-07
Handbook Of Stem Cell Therapy written by Khawaja Husnain Haider and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-07 with Science categories.
The handbook comprehensively reviews the therapeutic potential of stem cells and stem cell secretome-based cell-free strategies in regenerative medicine. The chapters in section I and section II respectively discuss the diverse applications of mesenchymal stem cells and non- mesenchymal stem cells, including skeletal myoblasts, endothelial progenitor cells, adipose tissue-derived stem cells, induced pluripotent stem cells, and neuronal stem cells in myocardial repair, inflammatory bowel disease, cognitive deficits, wound healing, retinal disorders, and COVID-19. The subsequent chapters in section IIIprimarily focused on the fast-emerging cell-free therapy approach in regenerative medicine for tissue repair and regeneration. These chapters review the impact of stem cell-derived secretome on various biological processes such as angiogenesis, neurogenesis, tissue repair, immunomodulation, musculoskeletal pathologies, wound healing, anti-fibrotic, and anti-tumorigenesis for tissue maintenance and regeneration.Lastly, section IV summarizes miscellaneous aspects of cell-based therapy, includingthe treatment advantages, opportunities, and shortcomings in stem cell-based therapy, potentially helping to refine future studies and translate them from experimental to clinical studies. Moreover, this section also has chapters on cancer stem cells as novel targets in cancer therapeutics. This Major Reference Book (MRW) is a valuable resource for researchers involved in stem cell research to understand the multifaceted therapeutic applications of stem cells and their derivative secretome in regenerative medicine.
Handbook Of Stem Cell Applications
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Author : Khawaja H. Haider
language : en
Publisher: Springer Nature
Release Date : 2024-03-25
Handbook Of Stem Cell Applications written by Khawaja H. Haider and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-25 with Science categories.
This handbook reviews the clinical applications of stem cell-based therapy. The book covers the clinical applications of stem cells in cardiovascular diseases, neurological and ocular diseases, pediatrics, and the role of cancer stem cell-derived exosomal microRNA payload in lung cancer. The chapter reviews emerging stem cell therapy and tissue engineering approaches in neurodegenerative diseases. The book further examines the applications of stem cells in various fields of dentistry, and for the regeneration of oral and non-oral tissues. The chapters also explore the application of 3D bioprinting in conjunction with bone marrow mesenchymal stem cells for the treatment of bone defects and state-of-the-art technology for bone and cartilage regeneration using mesenchymal stem cells. The book presents stem cell-based therapy against renal, pancreatic, and kidney diseases and examines the advantages of a novel hepatic stem for cirrhotic liver repair and regeneration. Lastly, the book provides methodological and procedural advancements in stem cell-based therapy, including the applications of single-cell sequencing in stem cell research. This handbook is a major one-stop reference for researchers working in regenerative medicine, cellular pharmacology, stem cell research in general, and those involved in specific areas of adult stem cells as well as embryonic and induced pluripotent stem cells.
Cardiovascular Applications Of Stem Cells
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Author : Khawaja H. Haider
language : en
Publisher: Springer Nature
Release Date : 2023-07-05
Cardiovascular Applications Of Stem Cells written by Khawaja H. Haider and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-05 with Science categories.
The book covers multifarious aspects of stem cell-based therapy for cardiovascular diseases. In addition to stem cells from different sources for cell-based therapy, it covers stem cell organoids and stem cell-derived exosomes in regenerative medicine. The book also encompasses advances in state-of-the-art infrastructure to improve the maturation aspects of pluripotent stem cells-derived cardiomyocytes using a novel scaffold-based cell culture system for cell delivery in experimental animal models and clinical settings. Besides the use of mesenchymal stem cells, the book includes chapters on the use of cardiac progenitor cells (CPCs), microtissue implantation, use of PSCs for valvulopathies, application of de-cellularized organ arrays as natural scaffolds for cardiac tissue engineering, use of epicardial stem cells, and skeletal myoblasts in cell-based therapy for myocardial regeneration. Besides the cell-based therapy approach, the book also reviews the stem cell-derived exosomes, their characteristics, and engineering strategies to enhance their therapeutic potential via targeting and drug loading and use in disease models. Additionally, the book also discusses the latest research on injectable hydrogels for cardiovascular regeneration and how hydrogel-based delivery protects the cells and their retention post-engraftment in the heart, a problem, which significantly reduces the efficacy of cell-based therapy.
Handbook Of Regenerative Medicine
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Author : Khawaja Husnain Haider
language : en
Publisher: CRC Press
Release Date : 2025-05-22
Handbook Of Regenerative Medicine written by Khawaja Husnain Haider and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-22 with Technology & Engineering categories.
This book comprehensively reviews cell-free therapy approaches, focusing on the therapeutic potential of mesenchymal stem cell-derived extracellular vesicles (EVs) and secretomes across various reparative and regenerative medicine fields. The initial chapters primarily provide foundational insights into the application of EVs in dentistry, cardiovascular pathologies, and kidney injury. Each chapter discusses the role of mesenchymal stem cell exosomes in targeted therapies for conditions like neurodegenerative disorders, ophthalmological diseases, and diabetes complications, examining the applications of EV-based techniques in personalized medical strategies. The subsequent chapters discuss the advanced diagnostic and therapeutic applications, including using EVs as biomarkers in liquid biopsies and novel tissue engineering and cell-free scaffolding techniques for organ rejuvenation and tissue regeneration. Additionally, this book examines the challenges and progress in transitioning these therapies from laboratory research to clinical applications, covering critical aspects of formulation, Good Manufacturing Practice (GMP) production, regulatory approval, and market access. With insights into emerging technologies like 3D cell scaffolding and theragnostic applications in cancer and neurodegenerative diseases, this book emphasizes the future of a cell-free approach in regenerative medicine. This book is a useful resource for researchers and students in regenerative medicine. Key Features: Provides insights into EV-based therapies and their role in regenerative medicine across multiple medical fields Discusses the potential of mesenchymal stem cell-derived exosomes in treating neurodegenerative, ophthalmological, and cardiovascular conditions Explores cell-free scaffolding for targeted tissue and organ regeneration Reviews the current regulatory, production, and clinical challenges in bringing cell-free therapies to market Explores cutting-edge theragnostic applications of EVs in oncology and neurological disorders
The Science Of Evolution And The Myth Of Creationism
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Author : Ardea Skybreak
language : en
Publisher: Insight Press, Inc
Release Date : 2006-09-01
The Science Of Evolution And The Myth Of Creationism written by Ardea Skybreak and has been published by Insight Press, Inc this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-01 with Science categories.
This clear, lively, and systematic presentation examines the scientific evidence for evolution and reaches for the widest possible audience—from scientific minds to those with no science background at all. Forcefully rejecting creationist objections to evolution and including a critique of Intelligent Design, it argues that they are part of a larger social agenda. With discussion that celebrates the fascination to be found in studying the diversity and complexity of life, this examination suggests with some urgency that the science of evolution is crucial to the existence of science itself.
Ecology And Evolution Of Cancer
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Author : Beata Ujvari
language : en
Publisher: Academic Press
Release Date : 2017-02-08
Ecology And Evolution Of Cancer written by Beata Ujvari and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-08 with Medical categories.
Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. - Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine - Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors - Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems - Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies
The Vegan Evolution
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Author : Gregory F. Tague
language : en
Publisher: Routledge
Release Date : 2022-06-14
The Vegan Evolution written by Gregory F. Tague and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-14 with Cooking categories.
Arguing for a vegan economy, this book explains how we can and should alter our eating habits away from meat and dairy through sociocultural evolution. Using the latest research and ideas about the cultural ecology of food, this book makes the case that through biological and, especially, cultural evolution, the human diet can gravitate away from farmed meat and dairy products. The thrust of the writing demonstrates that because humans are a cultural species, and since we are evolving more culturally than biologically, it stands to reason for health and environmental reasons that we develop a vegan economy. The book shows that for many good reasons we don’t need a diet of meat and dairy and a call is made to legislative leaders, policy makers, and educators to shift away from animal farming and inform people about the advantages of a vegan culture. The bottom line is that we have to start thinking collectively about smarter ways of growing and processing plant foods, not farming animals as food, to generate good consequences for health, the environment, and, therefore, animals. This is an attainable and worthy goal given the mental and physical plasticity of humans through cooperative cultural evolution. This book is essential reading for all interested in veganism, whether for ethical, environmental, or health reasons, and those studying the human diet from a range of disciplines, including cultural evolution, food ecology, animal ethics, food and nutrition, and evolutionary studies.
Self Organization As A New Paradigm In Evolutionary Biology
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Author : Anne Dambricourt Malassé
language : en
Publisher: Springer Nature
Release Date : 2022-07-04
Self Organization As A New Paradigm In Evolutionary Biology written by Anne Dambricourt Malassé and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-04 with Science categories.
The epistemological synthesis of the various theories of evolution, since the first formulation in 1802 with the transmission of the inherited characters by J.B. Lamarck, shows the need for an alternative synthesis to that of Princeton (1947). This new synthesis integrates the scientific models of self-organization developed during the second half of the 20th century based on the laws of physics, thermodynamics, and mathematics with the emergent evolutionary problematics such as self-organized memory. This book shows, how self-organization is integrated in modern evolutionary biology. It is divided in two parts: The first part pays attention to the modern observations in paleontology and biology, which include major theoreticians of the self-organization (d’Arcy Thompson, Henri Bergson, René Thom, Ilya Prigogine). The second part presents different emergent evolutionary models including the sciences of complexity, the non-linear dynamical systems, fractals, attractors, epigenesis, systemics, and mesology with different examples of the sciences of complexity and self-organization as observed in the human lineage, from both internal (embryogenesis-morphogenesis) and external (mesology) viewpoints.
The Real Life Story Of Stem Cells
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Author : Bhaskar Vyas
language : en
Publisher: Concept Publishing Company
Release Date : 2021-01-01
The Real Life Story Of Stem Cells written by Bhaskar Vyas and has been published by Concept Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-01 with Social Science categories.
This book is an autobiographical narration of the research activities, with penchant and passion, by two leading clinicians who turned towards stem cell research in later years of their life. The book is about facts as they happened, it also includes fiction as it should be a part of any novel and there is fantasizing as well as what one would like to be in the future. Facts, fiction and fantasy are frequently flavoured with philosophy as well. The authors axiomatically classify themselves as philosophers. Advocating that philosophy is the mother of all disciplines, they narrate how they jumped into deep waters of expensive stem cell research. The book describes how did they blunder at times and also cites the appearance of guardian angels to salvage them. Floundering from cell biology to different kinds of stem cell applications, the book describes where they have now parked at a far horizon, on the edge of new discovery of a wonderful drug. They ignite a spark of caution with restrictive regulations. The book ends with reframing the poem by Rabindranath Tagore, "Into that heaven of regenerative medicine, my Father, let my country awake."