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Stem Cells Origins Of Cytokine Interactions


Stem Cells Origins Of Cytokine Interactions
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Stem Cells Origins Of Cytokine Interactions


Stem Cells Origins Of Cytokine Interactions
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Author : Prasad S. Koka
language : en
Publisher:
Release Date : 2019

Stem Cells Origins Of Cytokine Interactions written by Prasad S. Koka and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Medical categories.


CD34+ pluripotent hematopoietic stem cells (HSCs) are generally involved in all aspects of the human system as well as in the stem cell therapeutic strategies, as in bone marrow transplantation (BMT). This book deals with several original research articles on HSC proliferation and containment. Lineage directed differentiation of HSCs and use of easily available herbal extracts for greatly increased proliferation into erythrocytes to treat thrombocytopenia are herein reported. HSCs respond to the growth factors and the herbal medicine is a welcome substitute with lack of known side effects for treatment purposes. However molecular mechanisms as in signal transduction are more easily deciphered than those derived from the herbs which may well be taken up for future studies. Mutations in the signal transduction genes such as JAK-2 have been shown to cause dysregulation of the CD34+ cell differentiation causing erythrocytosis, which is the reverse of thrombocytopenia, both of which are undesirable clinical consequences. Erythrocytes have been shown to date back to ancient tissues from the fossils.



Immune Response Activation And Immunomodulation


Immune Response Activation And Immunomodulation
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Author : Rajeev Tyagi
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-04-17

Immune Response Activation And Immunomodulation written by Rajeev Tyagi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-17 with Medical categories.


Immune Response Activation and Immunomodulation has been written to address the perceived needs of both medical school and undergraduate curricula and to take advantage of new understandings in immunology. We have tried to achieve several goals and present the most important principles governing the function of the immune system. Our fundamental objective has been to synthesize the key concepts from the vast amount of experimental data that have emerged in the rapidly advancing field of immunology. The choice of what is most important is based on what is most clearly established by experimentation, what our students find puzzling, and what explains the wonderful efficiency and economy of the immune system. Inevitably, however, such a choice will have an element of bias, and our bias is toward emphasizing the cellular interactions in immune response by limiting the description of many of the underlying biochemical and molecular mechanisms to the essential facts. This book gives an insight into the role of cytokines in activating immune response during pathogenic invasion. Immunomodulation, aryl hydrocarbons, the role of the protein defensin and nucleated cells in provoking immune response, Bcl protein/gene-based apoptotic pathways, and plant-derived phytochemical-mediated immune response are all central themes of this book.



Principles Of Cancer Biotherapy


Principles Of Cancer Biotherapy
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Author : Robert K. Oldham
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-08-29

Principles Of Cancer Biotherapy written by Robert K. Oldham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-29 with Medical categories.


At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches. By 2003 and the fourth edition, it was generally agreed that biopharmaceuticals were producing major opportunities for new cancer therapies. Cancer biotherapy has now truly matured into the fourth modality of cancer treatment. This fifth revised edition describes the tremendous progress that has been made in recent years using biologicals in cancer treatment. This book summarizes an evolving science and a rapidly changing medical practice in biotherapy. In this new millennium, it is now possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for a patient’s personalized cancer treatment. This was first envisioned in the 1987 initial edition of this textbook and is now a “new” and popular approach to cancer treatment. Some forms of cancer biotherapy use the strategy of tumor stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes. This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this fifth edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients for researchers and clinicians to explore and quickly apply these new opportunities in cancer biotherapy.



Mesenchymal Stem Cells In Human Health And Diseases


Mesenchymal Stem Cells In Human Health And Diseases
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Author : Ahmed El-Hashash
language : en
Publisher: Academic Press
Release Date : 2020-01-06

Mesenchymal Stem Cells In Human Health And Diseases written by Ahmed El-Hashash and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-06 with Science categories.


Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world



Guidebook To Cytokines And Their Receptors


Guidebook To Cytokines And Their Receptors
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Author : Nicos Nicola
language : en
Publisher: Sambrook and Tooze Publication at Oxford University Press
Release Date : 1994

Guidebook To Cytokines And Their Receptors written by Nicos Nicola and has been published by Sambrook and Tooze Publication at Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with History categories.


The number of cytokines and related growth factors has increased dramatically in recent years to several dozen. This text provides a succinct reference manual for all known cytokines, growth factors, interleukins and lymphokines as well as their receptors.



The European Blood And Marrow Transplantation Textbook For Nurses


The European Blood And Marrow Transplantation Textbook For Nurses
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Author : Michelle Kenyon
language : en
Publisher: Springer
Release Date : 2018-03-14

The European Blood And Marrow Transplantation Textbook For Nurses written by Michelle Kenyon and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-14 with Medical categories.


This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.



The Cytokine Factsbook And Webfacts


The Cytokine Factsbook And Webfacts
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Author : Katherine A. Fitzgerald
language : en
Publisher: Elsevier
Release Date : 2001-09-03

The Cytokine Factsbook And Webfacts written by Katherine A. Fitzgerald and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-09-03 with Medical categories.


Completely revised and expanded, this second edition of The Cytokine FactsBook is the most up-to-date reference manual available for all current well-characterized interleukins, cytokines, and their receptors. An additional 52 cytokines are included, doubling the number of entries from the previous edition. The key properties of each cytokine are described and presented in a very accessible format with diagrams for each of the receptors. The Cytokine FactsBook includes free online access to the regularly updated Cytokine Webfacts. Cytokine Webfacts is a web-based comprehensive compendium of facts about cytokines and their receptors that includes a variety of data representations, such as text, signal pathway diagrams and 3D images. This exciting resource is integrated into other databases via hypertext links to provide a unique network, and contains a web-enabled version of RasMol for viewing structures.



Stromal Cells


Stromal Cells
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Author : Mani T. Valarmathi
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-01-23

Stromal Cells written by Mani T. Valarmathi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-23 with Science categories.


Stromal cells are connective tissue cells of any organ, and they support the function of the parenchymal cells of that particular organ. Stromal/stromal stem cells are fundamentally a heterogeneous population of cells with contradictory differentiation potential depending upon their environmental niche. Stromal cell biology is not only intriguing, but equally stromal cell ontogeny in vivo remains challenging. In recent years there has been substantial advances in our understanding of stromal cell biology, especially stromal cell isolation, characterization, differentiation, and interactions in physiological (epithelial-stromal interactions) as well as pathophysiological (stromal-cancer interactions) contexts. In addition, stromal cells are also utilized more and more as a therapeutic tool not only in the field of gene therapy but also in the translational field of tissue engineering and regenerative medicine. Therefore, the goal of this book is to consolidate the recent advances in the area of stromal/stromal stem cell biology covering a broad range of interrelated topics in a timely fashion and to disseminate that knowledge in a lucid way to a greater scientific audience. This book will prove highly useful for students, researchers, and clinicians in stem cell biology, developmental biology, cancer biology, pathology, oncology, as well as tissue engineering and regenerative medicine. This quick reference will benefit anyone desiring a thorough overview of stromal cell structure, function, and its therapeutic implications.



Principles Of Regenerative Medicine


Principles Of Regenerative Medicine
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Author : Anthony Atala
language : en
Publisher: Academic Press
Release Date : 2010-12-16

Principles Of Regenerative Medicine written by Anthony Atala and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-16 with Science categories.


Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs



Invertebrate Cytokines And The Phylogeny Of Immunity


Invertebrate Cytokines And The Phylogeny Of Immunity
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Author : Alain Beschin
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-10-10

Invertebrate Cytokines And The Phylogeny Of Immunity written by Alain Beschin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-10 with Science categories.


Based on the assumption that invertebrates as well as vertebrates possess factors regulating hematopoiesis, response to infection or wounding, studies dealing with the evolution of immunity have focused on the isolation and characterization of putative cytokine-related molecules from invertebrates. Until recently, most of our knowledge of cytokine- and cytokine receptor-like molecules in invertebrates has relied on functional assays and similarities at the physicochemical level. As such, a phylogenetic relationship between invertebrate cytokine-like molecules and invertebrate counterparts could not be convincingly demonstrated. In the present book, recent studies demonstrating cytokine-like activities and related signaling pathways in invertebrates are critically reviewed, focusing on findings from molecular biology and taking advantage of the completion of the genome from the fly Drosophila and the worm Caenorhabditis elegans.