Structural And Evolutionary Genomics
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Structural And Evolutionary Genomics
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Author : Giorgio Bernardi
language : en
Publisher: Elsevier
Release Date : 2005-12-19
Structural And Evolutionary Genomics written by Giorgio Bernardi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-19 with Science categories.
Structural genomics is the study of the DNA of living organisms. Evolutionary genomics is the study of the history of the genome. These subjects are closely interlinked. They are approached in this book using as a guideline the investigations carried out in the author's laboratory, relevant literature is critically reviewed and some general conclusions are presented. The author and his collaborators have studied a vast number of genomes, ranging from prokaryotes to human, using different approaches, including physical chemistry of DNA, viral integration and molecular cytogenetics. As the subtitle indicates the book discusses the fundamental importance of natural selection in shaping genomes. In terms of numbers, neutral and nearly neutral mutations represent most mutations, but a "regional" control is exerted by natural selection (essentially negative or purifying selection). A "neo-selectionist" model is proposed for genome evolution.· Summarizes the existing knowledge on genome organization and evolution in a self-containedbook· Discusses important open problem, without refraining from criticism wheneverappropriate
Models And Algorithms For Genome Evolution
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Author : Cedric Chauve
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-09-17
Models And Algorithms For Genome Evolution written by Cedric Chauve and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-17 with Computers categories.
This authoritative text/reference presents a review of the history, current status, and potential future directions of computational biology in molecular evolution. Gathering together the unique insights of an international selection of prestigious researchers, this must-read volume examines the latest developments in the field, the challenges that remain, and the new avenues emerging from the growing influx of sequence data. These viewpoints build upon the pioneering work of David Sankoff, one of the founding fathers of computational biology, and mark the 50th anniversary of his first scientific article. The broad spectrum of rich contributions in this essential collection will appeal to all computer scientists, mathematicians and biologists involved in comparative genomics, phylogenetics and related areas.
Bioinformatics And Molecular Evolution
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Author : Paul G. Higgs
language : en
Publisher: John Wiley & Sons
Release Date : 2013-04-30
Bioinformatics And Molecular Evolution written by Paul G. Higgs and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-30 with Science categories.
In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. This accessible text: provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students places bioinformatics in the context of evolutionary biology, including population genetics, molecular evolution, molecular phylogenetics, and their applications features end-of-chapter problems and self-tests to help students synthesize the materials and apply their understanding is accompanied by a dedicated website - www.blackwellpublishing.com/higgs - containing downloadable sequences, links to web resources, answers to self-test questions, and all artwork in downloadable format (artwork also available to instructors on CD-ROM). This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses.
Evolutionary Genomics And Systems Biology
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Author : Gustavo Caetano-Anoll¿s
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-26
Evolutionary Genomics And Systems Biology written by Gustavo Caetano-Anoll¿s and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-26 with Science categories.
A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.
Molecular And Genome Evolution
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Author : Dan Graur
language : en
Publisher: Sinauer
Release Date : 2015-01-01
Molecular And Genome Evolution written by Dan Graur and has been published by Sinauer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-01 with Science categories.
This book describes the driving forces behind the evolutionary process at the molecular and genome levels, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology and the analytical tools involved in dealing with molecular data from an evolutionary perspective, and the logic of evolutionary hypothesis testing. Evolutionary phenomena at the molecular level are detailed in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Numerous examples that support and clarify the theoretical arguments and methodological discussions are included.
Foundations Of Comparative Genomics
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Author : Arcady R. Mushegian
language : en
Publisher: Elsevier
Release Date : 2010-07-20
Foundations Of Comparative Genomics written by Arcady R. Mushegian and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-20 with Science categories.
This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics. - Presents an historic overview of genome biology and its achievements - Includes topics not covered in other books such as minimal and ancestral genomes - Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level - Critically reviews horizontal gene transfer and other contentious issues - Covers comparative virology as a somewhat overlooked foundation of modern genome science
Molecular Biology Of The Cell
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Author :
language : en
Publisher:
Release Date : 2004
Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.
Evolutionary Genetics
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Author : Charles W. Fox
language : en
Publisher: Oxford University Press
Release Date : 2006-04-27
Evolutionary Genetics written by Charles W. Fox and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-27 with Science categories.
Charles Fox and Jason Wolf have brought together leading researchers to produce a cutting-edge primer introducing readers to the major concepts in modern evolutionary genetics. This book spans the continuum of scale, from studies of DNA sequence evolution through proteins and development to multivariate phenotypic evolution, and the continuum of time, from ancient events that lead to current species diversity to the rapid evolution seen over relatively short time scales in experimental evolution studies. Chapters are accessible to an audience lacking extensive background in evolutionaryy genetics but also current and in-depth enough to be of value to established researchers in evolution biology.
Untangling Molecular Biodiversity Explaining Unity And Diversity Principles Of Organization With Molecular Structure And Evolutionary Genomics
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Author : Gustavo Caetano-anolles
language : en
Publisher: World Scientific
Release Date : 2020-11-20
Untangling Molecular Biodiversity Explaining Unity And Diversity Principles Of Organization With Molecular Structure And Evolutionary Genomics written by Gustavo Caetano-anolles and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-20 with Science categories.
Untangling Molecular Biodiversity presents a unique global framework to explain molecular and organismal biodiversity that is grounded in evolutionary genomics. This book will tackle important questions such as the origin of life, the emergence of biochemistry, the origin of viruses, the nature of the last universal common ancestor responsible for diversified life, the role of information and thermodynamics in evolution, the reason for having three cellular domains in life, and the centrality of modules in biology.This book will explore six themes: (1) Explanatory frameworks for biological organization; (2) Evolutionary patterns and biodiversity; (3) Molecular structure and evolutionary genomics; (4) A framework of persistence strategies that borrows from engineering and systems biology; (5) Use of this framework to explain diversity in the molecular world; and (6) Exploring the origin and evolution of cells and viruses.Consequently, this book represents a very unique collection of ideas that can attract the attention of a broad readership interested in life sciences/biology.
Index Medicus
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Author :
language : en
Publisher:
Release Date : 2004
Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.