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Structural Approaches To Sequence Evolution


Structural Approaches To Sequence Evolution
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Structural Approaches To Sequence Evolution


Structural Approaches To Sequence Evolution
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Author : Ugo Bastolla
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-26

Structural Approaches To Sequence Evolution written by Ugo Bastolla and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-26 with Science categories.


Recent advances in understanding the thermodynamics of macromolecules, the topological properties of gene networks, the organization and mutation capabilities of genomes, and the structure of populations make it possible to incorporate these key elements into a broader and deeply interdisciplinary view of molecular evolution. This book gives an account of such a new approach, through clear tutorial contributions by leading scientists.



Structural Approaches To Sequence Evolution


Structural Approaches To Sequence Evolution
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Author : Ugo Bastolla
language : en
Publisher:
Release Date : 2005

Structural Approaches To Sequence Evolution written by Ugo Bastolla and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.




International Workshop On Structural Approaches To Sequence Evolution Molecules Networks Populations


International Workshop On Structural Approaches To Sequence Evolution Molecules Networks Populations
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Author : International Workshop on Structural approaches to sequence evolution: molecules, networks, populations
language : en
Publisher:
Release Date : 2004

International Workshop On Structural Approaches To Sequence Evolution Molecules Networks Populations written by International Workshop on Structural approaches to sequence evolution: molecules, networks, populations and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.




Workshop Structural Approaches To Sequence Evolution Molecules Networks And Populations


Workshop Structural Approaches To Sequence Evolution Molecules Networks And Populations
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Author : Workshop Structural Approaches to Sequence Evolution: Molecules, Networks and Populations
language : en
Publisher:
Release Date : 2005

Workshop Structural Approaches To Sequence Evolution Molecules Networks And Populations written by Workshop Structural Approaches to Sequence Evolution: Molecules, Networks and Populations and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.




Sequence Evolution Function


Sequence Evolution Function
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Author : Eugene V. Koonin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Sequence Evolution Function written by Eugene V. Koonin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.


Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.



Molecular Data Analysis Using R


Molecular Data Analysis Using R
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Author : Csaba Ortutay
language : en
Publisher: John Wiley & Sons
Release Date : 2017-02-06

Molecular Data Analysis Using R written by Csaba Ortutay and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-06 with Medical categories.


This book addresses the difficulties experienced by wet lab researchers with the statistical analysis of molecular biology related data. The authors explain how to use R and Bioconductor for the analysis of experimental data in the field of molecular biology. The content is based upon two university courses for bioinformatics and experimental biology students (Biological Data Analysis with R and High-throughput Data Analysis with R). The material is divided into chapters based upon the experimental methods used in the laboratories. Key features include: • Broad appeal--the authors target their material to researchers in several levels, ensuring that the basics are always covered. • First book to explain how to use R and Bioconductor for the analysis of several types of experimental data in the field of molecular biology. • Focuses on R and Bioconductor, which are widely used for data analysis. One great benefit of R and Bioconductor is that there is a vast user community and very active discussion in place, in addition to the practice of sharing codes. Further, R is the platform for implementing new analysis approaches, therefore novel methods are available early for R users.



The Origins Of Evolutionary Innovations


The Origins Of Evolutionary Innovations
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Author : Andreas Wagner
language : en
Publisher: OUP Oxford
Release Date : 2011-07-14

The Origins Of Evolutionary Innovations written by Andreas Wagner and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-14 with Science categories.


The history of life is a nearly four billion year old story of transformative change. This change ranges from dramatic macroscopic innovations such as the evolution of wings or eyes, to a myriad of molecular changes that form the basis of macroscopic innovations. We are familiar with many examples of innovations (qualitatively new phenotypes that provide a critical benefit) but have no systematic understanding of the principles that allow organisms to innovate. This book proposes several such principles as the basis of a theory of innovation, integrating recent knowledge about complex molecular phenotypes with more traditional Darwinian thinking. Central to the book are genotype networks: vast sets of connected genotypes that exist in metabolism and regulatory circuitry, as well as in protein and RNA molecules. The theory can successfully unify innovations that occur at different levels of organization. It captures known features of biological innovation, including the fact that many innovations occur multiple times independently, and that they combine existing parts of a system to new purposes. It also argues that environmental change is important to create biological systems that are both complex and robust, and shows how such robustness can facilitate innovation. Beyond that, the theory can reconcile neutralism and selectionism, as well as explain the role of phenotypic plasticity, gene duplication, recombination, and cryptic variation in innovation. Finally, its principles can be applied to technological innovation, and thus open to human engineering endeavours the powerful principles that have allowed life's spectacular success.



Phytophthora


Phytophthora
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Author : Monica L. Gerth
language : en
Publisher: Springer Nature
Release Date : 2024-12-27

Phytophthora written by Monica L. Gerth and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-27 with Science categories.


This comprehensive volume examines techniques for studying Phytophthora species, a devastating group of plant pathogens that cause diseases in crops and natural ecosystems worldwide. The book compiles essential molecular techniques and methods, such as CRISPR-Cas genome editing for investigating pathogenicity and resistance, as well as tools for detecting, visualizing, and quantifying disease. Written for the highly successful Methods in Molecular Biology series, each chapter includes an introduction to its respective topic, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Phytophthora: Methods and Protocols equips researchers with the tools needed to address the challenges posed by these destructive microorganisms.



Structural Genomics And High Throughput Structural Biology


Structural Genomics And High Throughput Structural Biology
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Author : Michael Sundstrom
language : en
Publisher: CRC Press
Release Date : 2005-08-23

Structural Genomics And High Throughput Structural Biology written by Michael Sundstrom and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-23 with Medical categories.


Researchers in structural genomics continue to search for biochemical and cellular functions of proteins as well as the ways in which proteins assemble into functional pathways and networks using either experimental or computational approaches. Based on the experience of leading international experts, Structural Genomics and High Throughput Stru



Evolutionary Approaches To Protein Design


Evolutionary Approaches To Protein Design
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Author :
language : en
Publisher: Elsevier
Release Date : 2000-10-19

Evolutionary Approaches To Protein Design written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-10-19 with Science categories.


This is the first high-quality, comprehensive overview of the field of evolutionary protein design. Topics include new protein design strategies, the structures of laboratory-evolved proteins, the evolution of non-natural enzyme functions, and the theory of laboratory evolution.