Structural Genomics And High Throughput Structural Biology
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Structural Genomics And High Throughput Structural Biology
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Author : Michael Sundstrom
language : en
Publisher: CRC Press
Release Date : 2005-08-23
Structural Genomics And High Throughput Structural Biology written by Michael Sundstrom and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-23 with Medical categories.
Researchers in structural genomics continue to search for biochemical and cellular functions of proteins as well as the ways in which proteins assemble into functional pathways and networks using either experimental or computational approaches. Based on the experience of leading international experts, Structural Genomics and High Throughput Stru
Structural Proteomics
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Author : Bostjan Kobe
language : en
Publisher: Humana Press
Release Date : 2010-12-10
Structural Proteomics written by Bostjan Kobe and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-10 with Science categories.
The objective of this volume is to provide readers with a current view of all aspects of the 'pipeline' that takes protein targets to structures and how these have been optimised. This volume includes chapters describing, in-depth, the individual steps in the Structural Genomics pipeline, as well as less detailed overviews of individual Structural Genomics initiatives. It is the first book of protocols to cover techniques in a new and emerging field.
Structural Proteomics And Its Impact On The Life Sciences
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Author : Joel Sussman
language : en
Publisher: World Scientific
Release Date : 2008
Structural Proteomics And Its Impact On The Life Sciences written by Joel Sussman and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
The role played by structural proteomics in the first decade of the 21st century is equivalent to that played by the Human Genome Project in the last decade of the 20th century. The development of high-throughput technologies that permit the solution of hundreds of 3D structures of individual proteins, proteinOCoprotein complexes and proteinOCodrug complexes, just by one laboratory in a single year, will provide a knowledge base which will change the face of structural biology. This will have an immediate influence on medicinal chemistry and molecular pharmacology, as well as an increasing impact on such disciplines as neurobiology, developmental biology, immunology and molecular medicine.This book presents a state-of-the-art overview of the structural proteomics field, ranging from policy issues related to funding and goals, through the high-throughput procedures for protein production, to the solution of the structures of proteins and higher-order entities, via a multidisciplinary approach involving molecular biology, X-ray crystallography, NMR and electron microscopy, as well as bioinformatics analysis. This is the first book to provide such a comprehensive coverage of a rapidly evolving field.
Structural Genomics And Drug Discovery
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Author : Wayne F. Anderson
language : en
Publisher: Springer Nature
Release Date : 2014-07-08
Structural Genomics And Drug Discovery written by Wayne F. Anderson and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Medical categories.
Structural Genomics and Drug Discovery: Methods and Protocols focuses on high throughput structure determination methods and how they can be applied to lay the groundwork for structure aided drug discovery. The methods and protocols that are described can be applied in any laboratory interested in using detailed structural information to advance the initial stages of drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Structural Genomics and Drug Discovery: Methods and Protocols seeks to aid scientists in the further study into structural genomics approach as an efficient initial step toward drug discovery and the methods described will be useful to anyone interested in moving in this direction.
Structure Based Drug Discovery
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Author : Harren Jhoti
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-24
Structure Based Drug Discovery written by Harren Jhoti and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-24 with Science categories.
Structure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of the most exciting developments in the field, such as Fragment-based methods, are described in this book. The book describes the latest developments in technologies that can be used to obtain the 3-D structures including the high profile structural genomics approaches being utilised worldwide. The use of 3-D protein structures in new, Fragment-based, approaches to drug discovery are described in some detail. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions. In addition, developments in computational chemistry methodology are covered together with an assessment of practical applications.
Fundamentals Of Molecular Structural Biology
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Author : Subrata Pal
language : en
Publisher: Academic Press
Release Date : 2019-08-13
Fundamentals Of Molecular Structural Biology written by Subrata Pal and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-13 with Science categories.
Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche. - Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances - Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology - Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease
Chemoinformatics And Bioinformatics In The Pharmaceutical Sciences
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Author : Navneet Sharma
language : en
Publisher: Academic Press
Release Date : 2021-05-21
Chemoinformatics And Bioinformatics In The Pharmaceutical Sciences written by Navneet Sharma and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-21 with Medical categories.
Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences brings together two very important fields in pharmaceutical sciences that have been mostly seen as diverging from each other: chemoinformatics and bioinformatics. As developing drugs is an expensive and lengthy process, technology can improve the cost, efficiency and speed at which new drugs can be discovered and tested. This book presents some of the growing advancements of technology in the field of drug development and how the computational approaches explained here can reduce the financial and experimental burden of the drug discovery process. This book will be useful to pharmaceutical science researchers and students who need basic knowledge of computational techniques relevant to their projects. Bioscientists, bioinformaticians, computational scientists, and other stakeholders from industry and academia will also find this book helpful. - Provides practical information on how to choose and use appropriate computational tools - Presents the wide, intersecting fields of chemo-bio-informatics in an easily-accessible format - Explores the fundamentals of the emerging field of chemoinformatics and bioinformatics
Genetic Engineering Principles And Methods 28
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Author : Jane K. Setlow
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-21
Genetic Engineering Principles And Methods 28 written by Jane K. Setlow and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-21 with Technology & Engineering categories.
Genetic Engineering: Principles and Methods, published by Springer since 1979, presents state-of-the-art discussions in modern genetics and genetic engineering. This focus affirms a commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Recent volumes have covered gene therapy research, genetic mapping, plant science and technology, transport protein biochemistry, and viral vectors in gene therapy, among other topics.
Structural Proteomics And Its Impact On The Life Sciences
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Author : Joel Sussman
language : en
Publisher: World Scientific
Release Date : 2008
Structural Proteomics And Its Impact On The Life Sciences written by Joel Sussman and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Science categories.
Ranging from policy issues related to funding and goals, through high-throughput procedures for protein production, this text presents an overview of structural proteomics via a multidisciplinary approach involving molecular biology.
Issues In Biotechnology And Medical Technology Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Issues In Biotechnology And Medical Technology Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Science categories.
Issues in Biotechnology and Medical Technology Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biotechnology and Medical Technology Research and Application. The editors have built Issues in Biotechnology and Medical Technology Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biotechnology and Medical Technology Research and Application in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biotechnology and Medical Technology Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.