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Structural Nonparametric Models For The Analysis Of Longitudinal Data


Structural Nonparametric Models For The Analysis Of Longitudinal Data
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Structural Nonparametric Models For The Analysis Of Longitudinal Data


Structural Nonparametric Models For The Analysis Of Longitudinal Data
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Author : Colin O. Wu
language : en
Publisher: Chapman and Hall/CRC
Release Date : 2016-01-15

Structural Nonparametric Models For The Analysis Of Longitudinal Data written by Colin O. Wu and has been published by Chapman and Hall/CRC this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-15 with Mathematics categories.


This book covers the recent advancement of statistical methods for the analysis of longitudinal data. Real datasets from four large NIH-supported longitudinal clinical trials and epidemiological studies illustrate the practical applications of the statistical methods. This book focuses on the nonparametric approaches, which have gained tremendous popularity in biomedical studies. These approaches have the flexibility to answer many scientific questions that cannot be properly addressed by the existing parametric approaches, such as the linear and nonlinear mixed effects models.



Nonparametric Models For Longitudinal Data


Nonparametric Models For Longitudinal Data
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Author : Colin O. Wu
language : en
Publisher: CRC Press
Release Date : 2018-05-23

Nonparametric Models For Longitudinal Data written by Colin O. Wu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-23 with Mathematics categories.


Nonparametric Models for Longitudinal Data with Implementations in R presents a comprehensive summary of major advances in nonparametric models and smoothing methods with longitudinal data. It covers methods, theories, and applications that are particularly useful for biomedical studies in the era of big data and precision medicine. It also provides flexible tools to describe the temporal trends, covariate effects and correlation structures of repeated measurements in longitudinal data. This book is intended for graduate students in statistics, data scientists and statisticians in biomedical sciences and public health. As experts in this area, the authors present extensive materials that are balanced between theoretical and practical topics. The statistical applications in real-life examples lead into meaningful interpretations and inferences. Features: • Provides an overview of parametric and semiparametric methods • Shows smoothing methods for unstructured nonparametric models • Covers structured nonparametric models with time-varying coefficients • Discusses nonparametric shared-parameter and mixed-effects models • Presents nonparametric models for conditional distributions and functionals • Illustrates implementations using R software packages • Includes datasets and code in the authors’ website • Contains asymptotic results and theoretical derivations



Nonparametric Regression Methods For Longitudinal Data Analysis


Nonparametric Regression Methods For Longitudinal Data Analysis
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Author : Hulin Wu
language : en
Publisher: John Wiley & Sons
Release Date : 2006-05-12

Nonparametric Regression Methods For Longitudinal Data Analysis written by Hulin Wu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-12 with Mathematics categories.


Incorporates mixed-effects modeling techniques for more powerful and efficient methods This book presents current and effective nonparametric regression techniques for longitudinal data analysis and systematically investigates the incorporation of mixed-effects modeling techniques into various nonparametric regression models. The authors emphasize modeling ideas and inference methodologies, although some theoretical results for the justification of the proposed methods are presented. With its logical structure and organization, beginning with basic principles, the text develops the foundation needed to master advanced principles and applications. Following a brief overview, data examples from biomedical research studies are presented and point to the need for nonparametric regression analysis approaches. Next, the authors review mixed-effects models and nonparametric regression models, which are the two key building blocks of the proposed modeling techniques. The core section of the book consists of four chapters dedicated to the major nonparametric regression methods: local polynomial, regression spline, smoothing spline, and penalized spline. The next two chapters extend these modeling techniques to semiparametric and time varying coefficient models for longitudinal data analysis. The final chapter examines discrete longitudinal data modeling and analysis. Each chapter concludes with a summary that highlights key points and also provides bibliographic notes that point to additional sources for further study. Examples of data analysis from biomedical research are used to illustrate the methodologies contained throughout the book. Technical proofs are presented in separate appendices. With its focus on solving problems, this is an excellent textbook for upper-level undergraduate and graduate courses in longitudinal data analysis. It is also recommended as a reference for biostatisticians and other theoretical and applied research statisticians with an interest in longitudinal data analysis. Not only do readers gain an understanding of the principles of various nonparametric regression methods, but they also gain a practical understanding of how to use the methods to tackle real-world problems.



Methods And Applications Of Longitudinal Data Analysis


Methods And Applications Of Longitudinal Data Analysis
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Author : Xian Liu
language : en
Publisher: Elsevier
Release Date : 2015-09-01

Methods And Applications Of Longitudinal Data Analysis written by Xian Liu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-01 with Mathematics categories.


Methods and Applications of Longitudinal Data Analysis describes methods for the analysis of longitudinal data in the medical, biological and behavioral sciences. It introduces basic concepts and functions including a variety of regression models, and their practical applications across many areas of research. Statistical procedures featured within the text include: - descriptive methods for delineating trends over time - linear mixed regression models with both fixed and random effects - covariance pattern models on correlated errors - generalized estimating equations - nonlinear regression models for categorical repeated measurements - techniques for analyzing longitudinal data with non-ignorable missing observations Emphasis is given to applications of these methods, using substantial empirical illustrations, designed to help users of statistics better analyze and understand longitudinal data. Methods and Applications of Longitudinal Data Analysis equips both graduate students and professionals to confidently apply longitudinal data analysis to their particular discipline. It also provides a valuable reference source for applied statisticians, demographers and other quantitative methodologists. - From novice to professional: this book starts with the introduction of basic models and ends with the description of some of the most advanced models in longitudinal data analysis - Enables students to select the correct statistical methods to apply to their longitudinal data and avoid the pitfalls associated with incorrect selection - Identifies the limitations of classical repeated measures models and describes newly developed techniques, along with real-world examples.



Longitudinal Data Analysis


Longitudinal Data Analysis
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Author : Garrett Fitzmaurice
language : en
Publisher: CRC Press
Release Date : 2008-08-11

Longitudinal Data Analysis written by Garrett Fitzmaurice and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-11 with Mathematics categories.


Although many books currently available describe statistical models and methods for analyzing longitudinal data, they do not highlight connections between various research threads in the statistical literature. Responding to this void, Longitudinal Data Analysis provides a clear, comprehensive, and unified overview of state-of-the-art theory



Handbook Of Adaptive Designs In Pharmaceutical And Clinical Development


Handbook Of Adaptive Designs In Pharmaceutical And Clinical Development
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Author : Annpey Pong
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Handbook Of Adaptive Designs In Pharmaceutical And Clinical Development written by Annpey Pong and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Mathematics categories.


In response to the US FDA's Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to their flexibility and efficiency, especially during early phase development. Handbook of Adaptive Designs in Pharmaceutical and Clinical Development provides a comprehensive and unified presentation of the princip



The Work Of Raymond J Carroll


The Work Of Raymond J Carroll
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Author : Marie Davidian
language : en
Publisher: Springer
Release Date : 2014-06-06

The Work Of Raymond J Carroll written by Marie Davidian and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-06 with Mathematics categories.


This volume contains Raymond J. Carroll's research and commentary on its impact by leading statisticians. Each of the seven main parts focuses on a key research area: Measurement Error, Transformation and Weighting, Epidemiology, Nonparametric and Semiparametric Regression for Independent Data, Nonparametric and Semiparametric Regression for Dependent Data, Robustness, and other work. The seven subject areas reviewed in this book were chosen by Ray himself, as were the articles representing each area. The commentaries not only review Ray’s work, but are also filled with history and anecdotes. Raymond J. Carroll’s impact on statistics and numerous other fields of science is far-reaching. His vast catalog of work spans from fundamental contributions to statistical theory to innovative methodological development and new insights in disciplinary science. From the outset of his career, rather than taking the “safe” route of pursuing incremental advances, Ray has focused on tackling the most important challenges. In doing so, it is fair to say that he has defined a host of statistics areas, including weighting and transformation in regression, measurement error modeling, quantitative methods for nutritional epidemiology and non- and semiparametric regression.



Advanced Medical Statistics 2nd Edition


Advanced Medical Statistics 2nd Edition
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Author : Ying Lu
language : en
Publisher: World Scientific
Release Date : 2015-06-29

Advanced Medical Statistics 2nd Edition written by Ying Lu and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-29 with Medical categories.


The book aims to provide both comprehensive reviews of the classical methods and an introduction to new developments in medical statistics. The topics range from meta analysis, clinical trial design, causal inference, personalized medicine to machine learning and next generation sequence analysis. Since the publication of the first edition, there have been tremendous advances in biostatistics and bioinformatics. The new edition tries to cover as many important emerging areas and reflect as much progress as possible. Many distinguished scholars, who greatly advanced their research areas in statistical methodology as well as practical applications, also have revised several chapters with relevant updates and written new ones from scratch.The new edition has been divided into four sections, including, Statistical Methods in Medicine and Epidemiology, Statistical Methods in Clinical Trials, Statistical Genetics, and General Methods. To reflect the rise of modern statistical genetics as one of the most fertile research areas since the publication of the first edition, the brand new section on Statistical Genetics includes entirely new chapters reflecting the state of the art in the field.Although tightly related, all the book chapters are self-contained and can be read independently. The book chapters intend to provide a convenient launch pad for readers interested in learning a specific topic, applying the related statistical methods in their scientific research and seeking the newest references for in-depth research.



Biological Knowledge Discovery Handbook


Biological Knowledge Discovery Handbook
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Author : Mourad Elloumi
language : en
Publisher: John Wiley & Sons
Release Date : 2015-02-04

Biological Knowledge Discovery Handbook written by Mourad Elloumi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-04 with Computers categories.


The first comprehensive overview of preprocessing, mining, and postprocessing of biological data Molecular biology is undergoing exponential growth in both the volume and complexity of biological data and knowledge discovery offers the capacity to automate complex search and data analysis tasks. This book presents a vast overview of the most recent developments on techniques and approaches in the field of biological knowledge discovery and data mining (KDD) providing in-depth fundamental and technical field information on the most important topics encountered. Written by top experts, Biological Knowledge Discovery Handbook: Preprocessing, Mining, and Postprocessing of Biological Data covers the three main phases of knowledge discovery (data preprocessing, data processing also known as data mining and data postprocessing) and analyzes both verification systems and discovery systems. BIOLOGICAL DATA PREPROCESSING Part A: Biological Data Management Part B: Biological Data Modeling Part C: Biological Feature Extraction Part D Biological Feature Selection BIOLOGICAL DATA MINING Part E: Regression Analysis of Biological Data Part F Biological Data Clustering Part G: Biological Data Classification Part H: Association Rules Learning from Biological Data Part I: Text Mining and Application to Biological Data Part J: High-Performance Computing for Biological Data Mining Combining sound theory with practical applications in molecular biology, Biological Knowledge Discovery Handbook is ideal for courses in bioinformatics and biological KDD as well as for practitioners and professional researchers in computer science, life science, and mathematics.



Missing Data In Longitudinal Studies


Missing Data In Longitudinal Studies
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Author : Michael J. Daniels
language : en
Publisher: CRC Press
Release Date : 2008-03-11

Missing Data In Longitudinal Studies written by Michael J. Daniels and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-11 with Mathematics categories.


Drawing from the authors' own work and from the most recent developments in the field, Missing Data in Longitudinal Studies: Strategies for Bayesian Modeling and Sensitivity Analysis describes a comprehensive Bayesian approach for drawing inference from incomplete data in longitudinal studies. To illustrate these methods, the authors employ